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Ethyl 7-chloro-8-methyl-4-oxo-1, what is the chemical structure of 4-dihydroquinoline-3-carboxylate
The corresponding chemical structure of "ethyl + 7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate" is: its parent structure is quinoline, and there are two hydrogen atoms substituted at the 1,4 position of the quinoline ring (that is, the 1,4-dihydroquinoline structure), the 4 position is the oxygen atom substituted to form a carbonyl (4-oxo), the 7 position has a chlorine atom substituted (7-chloro), the 8 position has a methyl substituted (8-methyl), and the 3 position is connected to a carboxyl group to form an ethyl ester (ethyl carboxylate).
The core of this compound is a quinoline ring, which is a dicyclic aromatic hydrocarbon fused by a benzene ring and a pyridine ring. Now hydrogenation at positions 1 and 4 changes its conjugate system, and the carbonyl at position 4 makes this site have certain electrophilicity. The chlorine atom at position 7 and the methyl at position 8 have important effects on the physicochemical properties of the molecule, such as polarity and steric resistance. The carboxyl ethyl ester structure at position 3 endows the molecule with a certain lipid solubility. In the fields of organic synthesis and medicinal chemistry, such structures may affect the permeability of the compound to the cell membrane and the interaction with biological targets. This structure is common in some drug development and the design of bioactive organic compounds, and the change of different substituents can lead to significant differences in their biological activities and physicochemical properties.
Ethyl 7-chloro-8-methyl-4-oxo-1, what are the main uses of 4-dihydroquinoline-3-carboxylate
Ethyl 7 - chloro - 8 - methyl - 4 - oxo - 1,4 - dihydroquinoline - 3 - carboxylate (7 - chloro - 8 - methyl - 4 - oxo - 1,4 - dihydroquinoline - 3 - carboxylate), this substance has a wide range of uses, and each has its own strengths, and is used in the fields of medicine, pesticides and materials.
In the field of medicine, it is often a key intermediate for the creation of new antimicrobial drugs. Due to their unique chemical structure and biological activity, quinoline compounds can act on specific bacterial targets, or interfere with bacterial DNA replication, or hinder protein synthesis, thereby inhibiting bacterial growth and reproduction. Antibacterial drugs derived from this compound can deal with a variety of bacterial infections and protect the health of all living beings.
In terms of pesticides, this compound can be used as raw materials for the development of new insecticides and fungicides. It has a special mechanism of action against pests or pathogenic bacteria, or destroys the nervous system of pests, or interferes with the respiratory metabolism of pathogenic bacteria, helping crops resist the invasion of pests and diseases, and protecting the five grains.
In the field of materials, 7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester can be converted into functional materials with excellent performance through specific reactions. For example, in optical materials, the material is endowed with unique optical properties, such as fluorescence properties, used in optical display, etc.; in polymer materials, the mechanical properties and thermal stability of materials are improved, and the application scope of materials is expanded.
In conclusion, ethyl 7 - chloro - 8 - methyl - 4 - oxo - 1,4 - dihydroquinoline - 3 - carboxylate is of great significance in many fields and contributes a lot to the development of various industries. It is an indispensable and important compound.
Ethyl 7-chloro-8-methyl-4-oxo-1, what is the synthesis method of 4-dihydroquinoline-3-carboxylate
Synthesis of ethyl 7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate follows the conventional path of organic synthesis. The first method may be obtained by a multi-step reaction from suitable starting materials.
First take an aniline compound with a suitable substituent and carry out a condensation reaction with a chlorine-containing carbonyl compound. This condensation process requires a suitable temperature and a suitable catalyst to enable the nucleophilic addition-elimination reaction between the two to form a preliminary nitrogen-containing heterocyclic structure.
Then, the preliminary product is methylated. Select suitable methylation reagents, such as iodomethane or dimethyl sulfate, etc., in an alkaline environment, introduce methyl groups at specific positions of the heterocyclic ring to complete the addition of key substituents.
Subsequently, through esterification, the carboxyl group of the heterocyclic ring and ethanol are catalyzed by acid or other suitable conditions to form the ester structure of the target product ethyl 7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate. During the reaction process, attention should be paid to the precise control of the reaction conditions at each step, such as temperature, ratio of reactants, reaction time, etc., to ensure the efficiency and selectivity of each step of the reaction, and to improve the yield and purity of the final product. In this synthesis process, although the steps are complicated, following the principles of organic synthesis and careful operation, the target compound will be obtained.
Ethyl 7-chloro-8-methyl-4-oxo-1, what are the physical properties of 4-dihydroquinoline-3-carboxylate
Ethyl-7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ester, the physical properties of this substance are related to its morphology, melting point, solubility, density and other characteristics, which are quite important.
First of all, its shape, under room temperature, or solid powder, fine texture, and the color may be white or yellowish, depending on its purity.
As for the melting point, due to the interaction between atoms in the molecular structure, its melting point is relatively high, about a specific range (the specific value is determined according to the exact measurement). When the temperature rises to the melting point, the substance gradually melts from the solid state to the liquid state. The boiling point also has its value, which is the temperature required for the transformation of the substance from the liquid state to the gaseous state, reflecting the difficulty of the molecules breaking free from each other's attractive forces.
In terms of solubility, it may have a certain solubility in common organic solvents, such as ethanol and acetone. Due to the interaction force between the molecules of the organic solvent and the molecules of the substance, some molecules can be dispersed in the solvent. However, in water, due to its strong hydrophobicity of the molecular structure, the solubility is poor.
Density is also one of its physical properties. The density reflects the mass per unit volume of the substance and is related to the degree of molecular accumulation. Its density may vary slightly due to different preparation methods and purity, and is roughly within a certain range.
In summary, the morphology, melting point, solubility and density of ethyl-7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid esters are determined by their molecular structure, and have important guiding significance for their applications in many fields, such as chemical synthesis and drug development.
Ethyl 7-chloro-8-methyl-4-oxo-1, what is the market outlook for 4-dihydroquinoline-3-carboxylate
There are currently compounds ethyl + 7 - chloro - 8 - methyl - 4 - oxo - 1,4 - dihydroquinoline - 3 - carboxylate, and their market prospects are related to many aspects. This compound may have unique potential in the field of pharmaceutical research and development. Because its structure contains specific groups, or it can have affinity for certain disease targets, and then develop into new therapeutic drugs, it is expected to open up new therapeutic paths in the pharmaceutical market, attracting the attention of pharmaceutical companies and scientific research institutions.
In the chemical industry, it can be used as an intermediate in organic synthesis. With its structural characteristics, it can participate in a variety of chemical reactions, synthesize more complex and special properties of organic compounds, and provide key raw materials for the production of fine chemical products. It occupies an important position in the chemical industry chain. With the growth of demand for new raw materials in the chemical industry, its market may have room for expansion.
However, its market prospects are also challenged. R & D costs are high, and a lot of money needs to be invested in R & D and testing from the discovery of its potential applications to the realization of industrial production. And competition is fierce. Similar structural compounds may already exist in the market. If you want to stand out, you need to demonstrate unique advantages. In addition, strict regulations and policies, applications in the pharmaceutical and chemical fields must meet relevant standards and approvals, and compliance costs are also factors to consider.
Overall, ethyl + 7 - chloro - 8 - methyl - 4 - oxo - 1,4 - dihydroquinoline - 3 - carboxylate has an addressable market opportunity, but also faces challenges such as cost, competition, and regulations. If properly addressed, it may gain a place in the market.