As a leading Ethyl 6,7-difluoro-1-methyl-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of quinoline-3-carboxylate ethyl 6, 7-difluoro-1-methyl-4-oxo-4H- [1,3] thiazeto [3,2-a]
Alas! Nowadays, there is a chemical compound named Ethyl 6,7 - difluoro - 1 - methyl - 4 - oxo - 4H - [1,3] thiazeto [3,2 - a] quinoline - 3 - carboxylate, in order to clarify its chemical properties. This name indicates that there is a chemical compound.
The first name of its name, "Ethyl", is also ethyl, which is often used to have a chemical group, and its $C_2H_5 - $, which is related to carbon. "6,7-difluoro", expressed in the main 6th and 7th positions, each with a fluorine atomic phase, fluorine, active element, with "F". "1-methyl", 1 position has methyl $- CH_3 $. "4-oxo", 4 position has carbonyl $C = O $, carbonyl compounds often have special chemical properties.
"4H - [1,3] thiazeto [3,2 - a] quinoline" This part is the core skeleton of the compound. "Quinoline" quinoline, which is a nitrogen-containing compound, is fused with benzene-pyridine. And "[1,3] thiazeto" means that on this quinoline skeleton, the phase is [1,3], and there is a sulfur-containing and nitrogen-containing compound, which forms this special thickness.
The most "- 3 - carboxylate", there is a carboxylic acid ester group $-COO - $in the third position of Ming Ming, and this ethyl phase, that is, $- COOC_2H_5 $.
In this case, Ethyl 6,7 - difluoro - 1 - methyl - 4 - oxo - 4H - [1,3] thiazeto [3,2 - a] quinoline - 3 - carboxylate of the chemical, derived from the quinoline of the main body, a number of specific modification, ethyl, fluorine atoms, methyl, carbonyl and carboxylic acid ethyl ester, etc., in their respective positions, together with this complex and delicate molecules.
What are the main uses of Ethyl 6, 7-difluoro-1-methyl-4-oxo-4H- [1,3] thiazeto [3,2-a] quinoline-3-carboxylate
Ethyl 6,7 - difluoro - 1 - methyl - 4 - oxo - 4H - [1,3] thiazeto [3,2 - a] quinoline - 3 - carboxylate, this is an organic compound. It has a wide range of uses and is often a key intermediate in the synthesis of antibacterial drugs. Antibacterial drugs have significant therapeutic effect on infectious diseases caused by many bacteria, and can help the human body resist the invasion of bacteria and restore health.
In terms of pesticides, pesticides made from this raw material have a good control effect on crop pests. It can effectively inhibit the breeding and reproduction of pests, ensure the normal growth of crops, improve crop yield and quality, and lay a solid foundation for agricultural harvest.
In the field of organic synthesis, due to its unique chemical structure, it can be used as a key building block for the construction of more complex organic molecules. Through a series of organic reactions, chemists can ingeniously use its properties to create compounds with novel properties and uses, driving the continuous development of organic synthetic chemistry and providing a new material basis for materials science, drug development and many other fields.
What is the synthesis method of Ethyl 6, 7-difluoro-1-methyl-4-oxo-4H- [1,3] thiazeto [3,2-a] quinoline-3-carboxylate
Ethyl 6,7 - difluoro - 1 - methyl - 4 - oxo - 4H - [1,3] thiazeto [3,2 - a] quinoline - 3 - carboxylate is an organic compound, and its synthesis method is quite complicated, and it needs to be controlled by subtle methods. Multi-step reactions can be achieved.
The selection of starting materials is usually nitrogen-containing, sulfur-containing and fluorine-containing compounds with specific structures, which is the foundation for laying the structure of the target product.
The first step often involves the construction of quinoline structures. Or select a suitable aniline derivative and fluorine-containing β-ketoic acid ester, and conduct a condensation reaction under the condition of acid or base catalysis. This process is like building the cornerstone of a tall building, and the reaction temperature, time and catalyst dosage need to be precisely controlled. If the temperature is too high, it may cause side reactions to cluster and the product is impure; if the temperature is too low, the reaction will be slow and take a long time.
When the quinoline structure is initially formed, sulfur atoms and nitrogen atoms are introduced to construct the [1,3] thiazeto structure. In this step, a sulfur-containing reagent and a nitrogen-containing reagent may be used in a suitable organic solvent and react under specific reaction conditions. The properties of organic solvents, such as polarity and boiling point, have a great impact on the reaction process. The appropriate polarity can promote the dissolution of the reactants and the collision between molecules, accelerating the reaction; otherwise, it hinders the reaction.
The introduction of methyl is also crucial, and more suitable methylating reagents are selected to replace hydrogen atoms at specific positions in alkaline environments. The strength of the base and the activity of the methylating reagent need to be carefully considered, otherwise it is easy to cause methylation position deviation or incomplete reaction.
In the final esterification step, with the corresponding carboxylic acid and ethanol, under the action of the catalyst, the esterification reaction is carried out to generate the target product Ethyl 6,7 - difluoro - 1 - methyl - 4 - oxo - 4H - [1,3] thiazeto [3,2 - a] quinoline - 3 - carboxylate. In this step, the type and dosage of the catalyst and the water content of the reaction system are all related to the yield and purity of the esterification reaction.
After each step of the reaction, separation and purification methods such as column chromatography and recrystallization are required to ensure the purity of the intermediate and lay a good foundation for subsequent reactions. Ethyl 6, 7 - difluoro - 1 - methyl - 4 - oxo - 4H - [1, 3] thiazeto [3, 2 - a] quinoline - 3 - carboxylate can be successfully synthesized with such interlocking and careful handling.
What are the physicochemical properties of quinoline-3-carboxylate Ethyl 6, 7-difluoro-1-methyl-4-oxo-4H- [1,3] thiazeto [3,2-a]
Ethyl 6,7 - difluoro - 1 - methyl - 4 - oxo - 4H - [1,3] thiazeto [3,2 - a] quinoline - 3 - carboxylate is an organic compound. Its physical and chemical properties are unique and are described as follows:
- ** Appearance and Properties **: This compound is usually in the state of white to light yellow solid powder. This appearance is determined by its molecular structure arrangement and crystallization properties. Intermolecular forces prompt it to form a specific crystal form, which in turn presents this appearance.
- ** Melting Point **: The melting point is about 160 - 165 ° C. Chemical bonds within molecules and interactions between molecules, such as hydrogen bonds, van der Waals forces, etc., jointly maintain the crystal structure. When the temperature rises to the melting point, these forces are weakened, the crystal structure disintegrates, and the substance changes from a solid state to a liquid state.
- ** Solubility **: Slightly soluble in water, due to the relatively weak molecular polarity of the compound, it is difficult to form a strong enough interaction with water molecules to overcome the cohesion of water. However, it is soluble in common organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. In organic solvents, suitable interactions can be formed between molecules and solvent molecules to achieve dissolution. < Br > - ** Stability **: Under normal temperature and pressure and dry environment, it has certain stability. However, when encountering strong oxidizing agents, strong acids, and strong bases, the molecular structure is easily damaged. Because the molecule contains specific functional groups, such as carboxyl ester bonds, nitrogen-containing heterocycles, etc., these parts are prone to chemical reactions with the above substances, resulting in structural changes.
- ** Spectral properties **: In the infrared spectrum, there is a strong absorption peak at 1730-1750 cm. This is the characteristic absorption peak of ester carbonyl groups, reflecting the existence of ester groups in the molecule. The H-NMR spectrum can show the signals of hydrogen atoms in different chemical environments, and the position and number of hydrogen atoms in the molecule can be inferred according to the chemical shift, fragmentation and integral area of the signal.
The physicochemical properties of this compound are of key significance for its synthesis, separation, purification and application in related fields.
Ethyl 6, 7-difluoro-1-methyl-4-oxo-4H- [1,3] thiazeto [3,2-a] What is the application prospect of quinoline-3-carboxylate in the market?
Ethyl 6,7 - difluoro - 1 - methyl - 4 - oxo - 4H - [1,3] thiazeto [3,2 - a] quinoline - 3 - carboxylate is also an organic compound. In today's market, its application prospects are quite promising.
In the field of Guanfu medicine, this compound may have unique pharmacological activities. The specific groups contained in its structure may be able to bind to specific targets in organisms. Such as quinoline and thiazolo-ring structures, in past studies, are often associated with antibacterial, anti-inflammatory and anti-tumor activities. It can be used to treat diseases by inhibiting the activity of specific enzymes or interfering with intracellular signal transduction pathways. Therefore, in the process of new drug development, it may be a promising lead compound, which is expected to be modified and optimized to create new drugs with better curative effect and less side effects.
Furthermore, in the field of materials science, it also has potential applications. Because of its special physical and chemical properties endowed by its structure, it can be used to prepare functional materials. For example, in optical materials, its molecular structure may enable it to have unique optical properties, such as fluorescence emission, which can be applied to the preparation of fluorescent probes for biological imaging, environmental monitoring and other fields to achieve high sensitivity detection of specific substances.
In the chemical industry, it may be used as an intermediate in organic synthesis. With its structural activity checking point, it can participate in many organic reactions, and through a series of chemical transformations, more compounds with complex structures and specific functions can be derived, which contributes to the diversified development of chemical products.
In summary, Ethyl 6,7 - difluoro - 1 - methyl - 4 - oxo - 4H - [1,3] thiazeto [3,2 - a] quinoline - 3 - carboxylate in medicine, materials, chemical industry and other fields have shown a very broad application prospects, over time, through in-depth research and development, will be able to contribute to the progress of various fields of extraordinary power.