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What is the chemical structure of Ethyl 4-chloro-7, 8-dimethylquinoline-3-carboxylate
The name of the organic compound is "Ethyl 4 - chloro - 7,8 - dimethylquinoline - 3 - carboxylate". To understand its chemical structure, you should follow the rules of organic chemistry and analyze its name to know its structure.
"Ethyl", ethyl is also known as - C ² H, which is one of the substituents of organic compounds, often connected to the main chain or ring. "Carboxylate" Epicarboxylate, its structure is - COO -, and it is followed by "Ethyl", which can be known as the structure of carboxylic acid and ethanol esters, that is - COOC 2O H.
"4-chloro" is shown in the main structure, with a chlorine atom substituted at the 4th position. The chlorine atom is a halogen element, represented by -Cl.
"7,8-dimethyl" means that the 7th and 8th positions of the main structure each have a methyl substitution. The methyl group is -CH.
"quinoline" is called a quinoline ring. The quinoline ring is a nitrogen-containing heterocycle. Its basic structure is formed by fusing a benzene ring with a pyridine ring.
In summary, the chemical structure of "Ethyl 4-chloro-7,8-dimethylquinoline-3-carboxylate" is as follows: the quinoline ring is the backbone, and the carboxylic acid ethyl ester-COOC -2 H is connected at the 3rd position, the chlorine atom-Cl is connected at the 4th position, and the methyl-CH is connected at the 7th and 8th positions. This structure integrates the characteristics of the quinoline ring and the properties of each substituent, and may be of great significance in the fields of organic synthesis and pharmaceutical chemistry.
What are the main uses of Ethyl 4-chloro-7, 8-dimethylquinoline-3-carboxylate
Ethyl 4-chloro-7,8-dimethylquinoline-3-carboxylate, Chinese name or ethyl 4-chloro-7,8-dimethylquinoline-3-carboxylate. This substance has a wide range of uses and is of important value in many fields.
In the field of medicinal chemistry, or can be used as a key intermediate. Geinquinoline compounds often have unique biological activities and can be converted into drugs with antibacterial, anti-inflammatory, anti-tumor and other pharmacological activities through specific chemical reactions. For example, by modifying its structure, or it can be combined with specific biological targets, so as to exert the corresponding therapeutic effect and make extraordinary contributions to the development of new drugs.
In the field of materials science, it may also exhibit unique properties. Some quinoline derivatives may be applied to organic Light Emitting Diodes (OLEDs), solar cells and other materials due to their special optical and electrical properties. Ethyl 4-chloro-7,8-dimethylquinoline-3-carboxylate through rational molecular design and modification may endow these materials with better photoelectric properties, improve their efficiency and stability, and then promote the development of materials science.
In the field of pesticide chemistry, it may also make a name for itself. Quinoline compounds may have inhibitory or killing effects on certain pests and pathogens. After research and development, they may be made into high-efficiency, low-toxicity and environmentally friendly pesticide products, providing new ways and methods for agricultural pest control and contributing to the sustainable development of agriculture.
What are the synthesis methods of Ethyl 4-chloro-7, 8-dimethylquinoline-3-carboxylate
Ethyl 4-chloro-7,8-dimethylquinoline-3-carboxylate is an organic compound. There are many synthesis methods for it. In the context of "Tiangong Kaiji", although there is no modern precise instrument and mature theory, it can also be explored from the traditional chemical operation ideas.
First, it can be started by aromatics containing corresponding substituents. Aromatic hydrocarbons with methyl substitutions are used as raw materials and chlorine atoms are introduced through halogenation reaction. This halogenation reaction may require a specific halogenation reagent to be carried out at a suitable temperature and in the presence of a catalyst. For example, chlorine gas or chlorination agents are used to chlorinate specific positions of aromatics under the catalytic conditions of light or Lewis acid to obtain aromatic hydrocarbon derivatives containing chlorine and methyl.
Subsequently, a quinoline ring is constructed by cyclization reaction. Such aromatic derivatives can be reacted with reagents containing carboxyl groups and nitrogen sources under appropriate condensation conditions. This condensation process may require the participation of heating and dehydrating agents to promote the formation of intra-molecular rings to form a quinoline skeleton, while the carboxyl groups are retained in suitable positions.
Finally, the resulting quinoline derivatives are reacted with ethanol under the action of esterification reagents to achieve esterification of carboxyl groups to generate Ethyl 4-chloro-7,8-dimethylquinoline-3-carboxylate. The esterification reaction may require a catalyst such as concentrated sulfuric acid, and under the condition of heating and refluxing, the carboxyl groups are dehydrated and condensed with ethanol hydroxyl groups to achieve the synthesis of the target product.
Although the technology of "Tiangong Kaiwu" is limited in the era, through the ingenious combination and practice of common chemical reactions, a way to synthesize this compound may be found.
What are the physical properties of Ethyl 4-chloro-7, 8-dimethylquinoline-3-carboxylate
Ethyl 4-chloro-7,8-dimethylquinoline-3-carboxylate is an organic compound with unique physical properties. Its appearance may be a crystalline solid, due to the structure of benzene ring and heterocycle, the intermolecular force results in this state.
This compound has a specific melting point and boiling point. The melting point is the temperature at which a substance changes from solid to liquid, and the melting point can be determined by measuring its purity. The boiling point is the temperature at which a substance changes from liquid to gas, and its boiling point is affected by the intermolecular force and the relative molecular mass.
In terms of solubility, because the molecule contains polar carboxyl ethyl ester groups and non-polar aromatic rings, it has good solubility in organic solvents such as ethanol and acetone. Due to its similar miscibility principle, the polar part interacts with the polar group of the organic solvent, and the non-polar aromatic ring interacts with the non-polar part of the organic solvent. In water, the solubility is poor due to the limited polarity of the whole.
Density is also an important physical property. Compared with other related compounds, its density can reflect the degree of tight packing of molecules and the relative molecular mass size, which helps to separate and purify them.
In addition, the compound has certain stability, and some chemical bonds in the molecule may break or rearrange under extreme conditions such as strong acid, strong base or high temperature. Because it contains chlorine atoms, ester groups and other active sites, it is easy to participate in chemical reactions such as nucleophilic substitution, and has potential application value in the field of organic synthesis.
Ethyl 4-chloro-7, 8-dimethylquinoline-3-carboxylate What are the precautions in storage and transportation?
Ethyl 4-chloro-7,8-dimethylquinoline-3-carboxylate is ethyl 4-chloro-7,8-dimethylquinoline-3-carboxylate. During storage and transportation, there are many matters to be paid attention to.
The nature of this compound may be more active. When storing, the temperature and humidity of the environment are the first priority. A cool, dry place should be selected, away from direct sunlight. Due to light and high temperature, it may decompose and deteriorate. At high temperature, the chemical bonds in the molecule may be more easily broken, triggering chemical reactions; if the humidity is high, or hydrolyzed by moisture, its chemical structure and properties will be changed.
Furthermore, the storage place must be well ventilated. Due to its volatility, it may accumulate in a closed space, and the concentration is too high. One may damage the storage container, and the other may pose a safety hazard. In case of open fire, static electricity, etc., it may cause combustion or explosion.
During transportation, the packaging must be solid and reliable. Suitable packaging materials, such as sturdy plastic drums or metal drums lined with special protective materials, should be used to prevent package damage and material leakage due to collision and extrusion. And the transportation tool should also be clean and dry, with no other chemical residues, to avoid reaction with it.
In addition, this compound may be toxic and irritating, and storage and transportation personnel should be professionally trained to be familiar with its characteristics and emergency treatment methods. If there is a leak, it should be dealt with promptly according to the plan to avoid polluting the environment and endangering human health. In short, careful and proper handling of storage and transportation can ensure the quality and safety of Ethyl 4-chloro-7,8-dimethylquinoline-3-carboxylate.