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What is the chemical structure of DL-3- (2-Dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride
DL-3- (1,2-dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride, this is an organic compound. In its structure, the amino and carboxyl groups of alanine are common functional groups, while the 3- (1,2-dihydro-2-oxo-quinoline-4-yl) part is a unique substituent.
Quinoline ring is an important heterocyclic structure and is common in many bioactive molecules and drugs. 1,2-Dihydro-2-oxo-quinoline-4-yl. In this compound, the quinoline ring has a dihydro structure at positions 1 and 2, and the 2 positions are oxo-carbonyl. Alanine is connected to the quinoline derivative and forms a connection on the 3-position carbon. The hydrochloride form indicates that there is a salt ion bound to the amino group in the compound, which enhances its water solubility and stability.
Looking at this structure, it may have acid-base properties. Because the carboxyl group is acidic, the amino group may exhibit alkalinity under appropriate conditions after binding to the hydrochloride group. And the conjugated structure of the quinoline ring endows the compound with a specific electron cloud distribution and reactivity. The compounds with this structure may have potential applications in the field of medicinal chemistry, because quinoline derivatives often have diverse biological activities, and alanine is a natural amino acid, which may affect their metabolism and pharmacological effects in vivo.
What are the physical properties of DL-3- (2-Dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride
DL-3- (1,2-dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride, this is an organic compound. It has many physical properties, let me tell them one by one.
Looking at its properties, it is often in the state of white to quasi-white crystalline powder, which is the appearance that can be seen. In terms of solubility, it has a certain solubility in water. Water is the solvent of all things. This compound can be dissolved in water because of the interaction between its molecular structure and water molecules. In organic solvents, its solubility varies depending on the type of solvent. Polar organic solvents such as ethanol may have good solubility. Due to the principle of "similar miscibility", polar molecules and polar molecules are easily attracted to each other and miscible.
Melting point is also an important physical property. The melting point of this compound has been determined to have a specific value. The determination of the melting point can help to identify its purity. Pure, the melting point is fixed and sensitive; if it contains impurities, the melting point is reduced and the melting range is widened. The level of melting point is closely related to the intermolecular force. The stronger the intermolecular force, the more energy is required to melt it, the higher the melting point.
In addition, its stability also needs to be considered. Under normal temperature and pressure, without special chemical environmental stimulation, the compound is relatively stable. In case of extreme conditions such as high temperature, strong acid and strong base, its molecular structure may be damaged, chemical reactions occur, and chemical properties change. This is a summary of the physical properties of DL-3- (1,2-dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride, which is of great significance in chemical research and related application fields.
What is the main use of DL-3- (2-Dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride
DL-3- (1,2-dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride is an organic compound. Its main uses are quite extensive, and it is often used as a potential drug intermediate in the field of pharmaceutical research and development. The structure of geinquinoline has various biological activities, such as antibacterial, anti-inflammatory, anti-tumor, etc. Compounds constructed on its basis may exhibit unique pharmacological effects and lay the foundation for the creation of new drugs.
In chemical research, it can be used as a reaction substrate to help explore novel organic synthesis methods and paths. Through the investigation of its chemical properties, efficient, green and selective synthesis strategies can be developed, enriching the treasure house of organic synthetic chemistry.
In the field of materials science, or through specific chemical reactions, it can be introduced into polymer materials or functional materials, endowing materials with special properties, such as optics, electricity or biocompatibility, and then expanding the application field of materials, emerging in biomedical materials, optoelectronic materials, etc.
This compound has important potential application value in many fields such as medicine, chemistry and materials, and is like a shining cornerstone, contributing to the progress of related fields.
What are the preparation methods of DL-3- (2-Dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride
The preparation method of DL-3- (1,2-dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride is difficult to find in ancient books, but according to today's chemical technology, the following ways can be found.
First, ethyl 4-chloroacetoacetate and o-aminobenzaldehyde are used as starting materials. In a suitable reaction vessel, the two undergo a condensation reaction under specific catalysts and reaction conditions to form key intermediates. This process requires precise control of temperature, pH and reaction time to ensure that the reaction proceeds in the desired direction. Subsequently, the intermediate is converted into the precursor of the target product through a series of steps such as hydrolysis and acidification. Finally, by reacting with hydrogen chloride gas or hydrochloric acid solution to form a salt, DL-3- (1,2-dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride can be obtained.
Second, 4-methyl-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid can also be used as a raw material. First, specific groups are modified to introduce suitable active groups to enhance its reactivity. Then, the desired molecular structure is constructed by substitution reaction with alanine-related derivatives under the action of specific reagents. After the reaction is completed, the impurities are removed through fine operations such as separation and purification, and finally the compound is prepared by salt-forming reaction.
During the preparation process, the conditions of each step of the reaction need to be strictly controlled. The purity of the reagent used, the reaction temperature, pressure, reaction time and many other factors have a great impact on the purity and yield of the product. And after each step of the reaction is completed, the reaction process needs to be monitored by suitable analysis and testing methods, such as thin-layer chromatography, high-performance liquid chromatography, etc., to ensure the quality of the product.
What are the precautions for storing and using DL-3- (2-Dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride?
DL-3- (1,2-dihydro-2-oxo-quinoline-4-yl) alanine hydrochloride, this is a special chemical substance. When storing and using, many matters need to be paid attention to.
Let's talk about storage first. This substance should be stored in a dry, cool and well-ventilated place. Because it may be quite sensitive to humidity, if the environment is humid, moisture can easily interact with it, causing its chemical properties to change and even deteriorate. A cool environment can avoid chemical reactions caused by excessive temperature, which can damage the stability of the substance. Good ventilation can disperse harmful gases that may evaporate in time and keep the storage environment safe.
Furthermore, it should be stored separately from oxidizing agents, acids, alkalis, etc. This substance is chemically active, and contact with the above substances may cause severe chemical reactions, causing serious consequences such as combustion and explosion. Storage containers must also be selected correctly to ensure that they are well sealed. Containers made of glass or specific plastic materials are commonly used to prevent substances from leaking and invading external substances.
As for use. Before use, it is necessary to fully understand its chemical properties and safety data. Experimenters need appropriate protective equipment, such as protective glasses, gloves, and protective clothing. Because it may be irritating, if accidentally touched with the skin or eyes, it will cause injury. The operation should be carried out in a fume hood. If used in an open space, the volatile gas will endanger human health. During use, strictly control the dosage and reaction conditions. Excessive dosage or improper conditions may cause the reaction to go out of control. After use, properly dispose of the remaining substances and waste. According to relevant regulations, do not discard them at will to prevent environmental pollution.