Cinchocaine
Quinoline Thiophene Imidazole Thiazole
Cinchocaine
Name Cinchocaine
Chemical Formula C19H27N3O2
Molar Mass 329.437 g/mol
Appearance White to off - white crystalline powder
Solubility Slightly soluble in water, soluble in ethanol, chloroform
Pka 8.4
Melting Point 90 - 93 °C
Pharmacological Class Local anesthetic
Mechanism Of Action Blocks voltage - gated sodium channels
Uses Spinal anesthesia, topical anesthesia for hemorrhoids etc.
FAQ

What are the main benefits of Cinchocaine?

Cocaine has the ability of strong local anesthesia. Its use can also block the transmission of nerve impulses, causing temporary loss of sensation in the local area, and pain and itching are unknown.

In the medical tract, cocaine is often used for surgery. Or the treatment of minor injuries, or the need for major surgery, all rely on it to reduce the pain of the patient. For example, when cutting carbunx and removing the mass, cocaine is applied to make the affected area unconscious, and the doctor can operate calmly, and the patient has no pain.

It can also be used for obstetric delivery. When the mother is in labor, cocaine can be used to relieve the severe pain of childbirth. It can make local anesthesia of the perineum, help the fetus to be delivered smoothly, and the pain of the mother is slightly lighter.

And in the treatment of anorectal diseases, it is also more common. The treatment of hemorrhoid fistula, the treatment of anal fissure, and cocaine can all make anal peripheral anesthesia, which is convenient for treatment and reduces the suffering of patients.

However, although its nature is good and numb, it must be used with caution. Excessive dosage may cause adverse reactions, such as dizziness, nausea, and even life-threatening. Therefore, when a doctor applies medicine, he must carefully review the patient's condition and determine the dosage in order to be safe and effective.

What are the side effects of Cinchocaine?

Cocaine, also have all kinds of side effects. Although the drug can relieve pain, but the disease involved, must not be ignored.

The first to bear the brunt, the impact on the central nervous system. Excessive use, easy to cause excitement, such as convulsions, tremors, etc. Geinxin cocaine can disrupt the normal transmission of neurotransmitters, nerve cells excitability abnormality. Then, or turned into a state of depression, causing respiratory depression, which is a danger to life. Gai respiratory center is affected by it, the function is blocked, and the breath is difficult to smooth.

Second, it is also unfavorable to the cardiovascular system. Can weaken the contractility of the myocardium and reduce the function of the heart pumping blood. And vasodilation, blood pressure or drop. This is because the drug acts on cardiomyocytes and vascular smooth muscle, causing their function to mutate. If the blood pressure drops too much, the blood supply to the brain and various organs is insufficient, and various diseases occur.

Furthermore, allergies are not uncommon. Under individual differences, some people are exposed to cocaine, which can trigger abnormal immune system reactions. Mild skin itching, erythema, severe interlaryngeal edema, anaphylactic shock. This is all because the immune system mistakenly recognizes it as a foreign enemy, rises up to attack, causing body disorders.

There is also the problem of local irritation. In the local area of the drug, there may be pain and redness. It is because the drug irritates the local tissue, causing tissue inflammation. If used repeatedly, the damage will be exacerbated, or it will be difficult to heal.

Looking at it, although cocaine has the power of analgesia, it also has many side effects. When doctors use it, they should weigh the pros and cons and act cautiously to ensure the well-being of patients and avoid all kinds of disasters.

What are the applicable groups of Cinchocaine?

Cocaine is a medicine for local anesthesia. It is suitable for people who are quite particular about it.

People who need local anesthesia for surgery can use this medicine. Such as surgery, operations on limbs, skin and other parts, in order to temporarily lose local pain, so that the doctor can perform the operation, cocaine can be used. The surgeon smears it and injects it into the operation area, so that the patient does not feel pain, and the operation can be carried out smoothly.

Another example is anorectal diseases, hemorrhoid fistulae require surgery. In order to relieve severe pain in the patient during surgery, cocaine can be used as a local anesthesia option, which can dull the pain around the anus. When the doctor treats, the patient suffers less pain.

However, pregnant women and breastfeeding women should use it with caution. The fetus and swaddling baby in the womb are delicate, and cocaine may affect the development of the fetus through the mother, or be passed on to the baby with milk, resulting in adverse consequences.

In addition, people who are allergic to cocaine must not use it. Such people are afraid of allergies, mild skin itching, rash, severe cases may cause breathing difficulties, shock, and endanger life.

The elderly and children, because their physiological functions are different from ordinary people, must also be cautious when using drugs. The function of the organs of the elderly is gradually declining, and the body of children is still developing. Therefore, the metabolism and tolerance of drugs are different from those of adults. Therefore, when using cocaine, the dosage should be carefully considered to ensure the safety of medication.

How is Cinchocaine used?

In the case of cinchocaine, it is also a drug for topical local anesthesia. The first way to use it is to clean the affected area, so as to protect the effect of the drug. Or as a genus of cream and ointment, apply it evenly to the skin that needs to be numb, which can stop the pain of the skin. If it is a mucosal place, it can also be used in an appropriate dosage form, such as a solution, and apply it carefully to achieve the purpose of mucosal anesthesia.

When using it, the amount must be carefully checked. Excessive amounts may cause adverse reactions, such as local allergies, rash and itching, redness and swelling; even, it may cause systemic toxicity, disturb the nerves and blood systems, and have convulsions and arrhythmia.

And the applicator must be familiar with its nature and use it according to the situation. Children, the elderly, and the infirm should be especially careful, and the amount should be reduced as appropriate. If you see any abnormalities during use, such as increased discomfort or severe allergies, stop using it immediately and seek medical attention. In short, when using cocaine, you must follow the doctor's instructions and abide by the law, so that the security can be complete and effective.

Does Cinchocaine interact with other medications?

In the case of cocaine, it is also a drug for local anesthesia. As for its interaction with other drugs, there may be interactions.

The nature of the drug, there are many phases and phases. Ocaine cocaine encounters other drugs, or increases its effect, or decreases its force, or even changes and harms the body. If it is combined with a drug that inhibits the central nervous system, or causes the risk of respiratory depression, both can inhibit the movement of the nerve. And if it is combined with a drug that mimics the sympathetic nerve, or causes a sharp rise in blood pressure, its sympathetic effect is superimposed.

Looking at the herbs and the compatibility of medicines, be cautious. Gu Yun: "There are seven emotions in medicine, and the harmony is seen." Ocaine cocaine is also among them. When it is combined with other medicines, its nature, its use, and its taboos must be scrutinized in detail. Doctors who use drugs are like walking on thin ice in the abyss, and they must study their pharmacology carefully to measure their advantages and disadvantages before they dare to apply them to patients.

The ancient books of the test, the combination of every word of medicine should not be ignored. The combination of cocaine and other medicines may be necessary and multiplied, or fearful and poisonous, or they may be evil, or on the contrary, they will cause great trouble. Therefore, when taking drugs, study the mutual nature of all medicines in detail, consult all classics, and refer to the previous sages, so that they are almost correct, so as to ensure the safety of the patient.