8 Oxyquinoline
Quinoline Thiophene Imidazole Thiazole
8-oxyquinoline
Chemical Formula C9H7NO
Molar Mass 145.16 g/mol
Appearance yellowish - green crystals
Odor characteristic
Melting Point 75 - 76 °C
Boiling Point 267 °C
Solubility In Water slightly soluble
Solubility In Organic Solvents soluble in ethanol, chloroform, etc.
Ph acidic solution properties
Stability stable under normal conditions
Toxicity moderately toxic
FAQ

What are the main uses of 8-oxyquinoline?

8-Hydroxyquinoline has a wide range of uses. One is used for the analysis of metal ions. It can be complexed with many metal ions to form complexes with specific properties. With this characteristic, it can be used in the field of chemical analysis for qualitative and quantitative determination of metal ions. For example, in ores, alloys and other samples, it can accurately identify and determine the types and contents of metal elements contained, and it is very useful in metallurgy, geological exploration and other industries.

Furthermore, it is also used in the pharmaceutical field. 8-Hydroxyquinoline and its derivatives often have pharmacological activities such as antibacterial and antiviral. After appropriate modification and modification, it can be made into drugs and used to treat a variety of diseases, making a lot of contributions to maintaining human health.

Again, in the field of materials science, 8-hydroxyquinoline can be used as a ligand to form metal-organic complexes with metal ions. Such complexes exhibit unique properties in luminescent materials, semiconductor materials, etc., providing assistance for the research and development of new materials, and have broad prospects in electronic devices, optical display and other industries.

In addition, in the field of agriculture, 8-hydroxyquinoline can be used as a fungicide, which can effectively inhibit the growth and reproduction of plant pathogens, thereby protecting crops from diseases, ensuring crop yield and quality, and has significant effects on the stable development of agriculture.

All of these, 8-hydroxyquinoline plays an important role in many fields, providing indispensable assistance for human production, life and scientific and technological progress.

What are the chemical properties of 8-oxyquinoline?

8-Hydroxyquinoline, with multiple chemical properties. It is a weak base, because the nitrogen atom does not share a common electron pair, it can form a salt with an acid. If it interacts with hydrochloric acid, 8-hydroxyquinoline hydrochloride is obtained, which is easily soluble in water.

It is also weakly acidic, and the hydrogen in the phenolic hydroxyl group can be partially ionized. In case of strong bases, it can form corresponding salts and exhibit acidic characteristics.

8-hydroxyquinoline contains a large π bond, has a certain conjugate system, shows a planar structure, has certain stability, and is relatively active in chemical properties. It can complex with a variety of metal ions. Because nitrogen and oxygen atoms have lone pairs of electrons, it can provide electron pairs to coordinate with metal ions. Like complexing with magnesium ions to form a stable complex, this property is often used in the analysis, separation and identification of metal ions.

In addition, 8-hydroxyquinoline has a wide range of uses in the field of organic synthesis. It can be used as an intermediate and participates in the preparation of many organic compounds. Because of its unique structure, it can introduce different functional groups through chemical reactions to expand its chemical uses. In the field of medicine, some of its derivatives have biological activities such as antibacterial and antiviral; in materials science, it can be used to prepare functional materials, and its complexing properties can be used to regulate material properties. In short, 8-hydroxyquinoline has rich chemical properties and is widely used.

In which industries is 8-oxyquinoline widely used?

8-Hydroxyquinoline has a wide range of uses and is used in various industries.

In the pharmaceutical industry, it is often used as a raw material for antibacterial and antimalarial drugs. With its certain antibacterial properties, it can make antibacterial preparations, help resist bacteria, and protect human health.

In the agricultural field, it is also indispensable. It can be used as a plant growth regulator, promoting crop growth and increasing its resistance to stress; and as a fungicide, protecting plants from diseases and ensuring abundant agricultural production.

In the chemical field, 8-hydroxyquinoline can be used as a metal ion chelating agent. In the separation, purification, and electroplating process of metal ions, it can show its skills, optimize the process, and improve the quality of products. < Br >
Furthermore, in the field of analytical chemistry, it is often used as an analytical reagent. It can sensitively detect and determine metal ions, providing an accurate basis for scientific research and detection work.

In the paint industry, it also has its own shadow. It can be added to coatings to increase the anti-corrosion and anti-mildew properties of coatings and extend the service life of coatings.

From this perspective, 8-hydroxyquinoline is widely used in many industries such as medicine, agriculture, chemical industry, analytical chemistry, coatings, etc., and plays a key role in the development of various industries.

What is the production process of 8-oxyquinoline?

8-Hydroxyquinoline is also an organic compound. The method of its preparation has existed in ancient times and has been improved.

In the past, 8-hydroxyquinoline was prepared by ingenious reaction, often using o-aminophenol and glycerol as raw materials, sulfuric acid as dehydrating agent, and arsenic pentoxide or nitrobenzene as oxidizing agent. The reaction process is quite complicated. First, under the action of sulfuric acid, o-aminophenol and glycerol carry out a condensation reaction, and the molecules combine with each other to construct a new structure. The addition of oxidizing agents such as arsenic pentoxide or nitrobenzene can promote the reaction to generate 8-hydroxyquinoline, helping it to achieve the desired product.

However, this ancient method has many drawbacks. The arsenic pentoxide used is highly toxic and harmful to the environment and human health. The reaction conditions are harsh, requiring a higher temperature and a specific environment. The operation is quite difficult, and the purity of the product is also difficult to achieve.

Later generations of craftsmen, in order to solve this dilemma, continue to study and find another way. Some use o-nitrophenol, o-aminophenol, etc. as starting materials, and 8-hydroxyquinoline can also be prepared by different reaction paths and conditions. The new process strives to be green and environmentally friendly, avoiding highly toxic substances, the reaction conditions are also milder, easier to control, and the purity and yield of the product are improved. Therefore, the preparation process of 8-hydroxyquinoline has been increasingly refined with the development of the times to meet the needs of all parties.

What are the precautions during the use of 8-oxyquinoline?

When using 8-oxyquinoline, there are many precautions to keep in mind.

Its properties are toxic, and safety procedures must be strictly followed when using it. Be well protected, wear protective clothing, gloves and goggles to prevent it from touching the skin and eyes. If you accidentally touch it, rinse it with plenty of water immediately. If the situation is serious, you need to seek medical attention immediately.

8-hydroxyquinoline should also be kept in the environment when storing. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources to avoid danger. At the same time, it should be stored separately from oxidants, acids and other substances to prevent mutual reaction.

In the process of use, accurate dose control is the key. Because of its dosage, it has a great impact on the reaction effect. If the dosage is too small, the reaction may be incomplete; if the dosage is too large, it may cause side reactions, and may cause waste and environmental pollution.

Furthermore, 8-hydroxyquinoline has different solubility in different solvents, so it is crucial to choose a suitable solvent. It needs to be carefully selected according to the specific reaction requirements to ensure that it can be fully dissolved and effective.

After use, the disposal of its waste should not be ignored. It should be properly disposed of in accordance with relevant environmental protection regulations and should not be discarded at will to avoid harm to the environment. In short, only in the process of using 8-hydroxyquinoline, pay attention to all of the above to ensure safe and efficient use.