8 Hydroxy 5 Quinolinesulfonic Acid
quinoline thiophene imidazole thiazole

8-HYDROXY-5-QUINOLINESULFONIC ACID

Taiy Chemical

Specifications

HS Code

530437

Chemical Formula C9H7NO5S
Molecular Weight 241.22 g/mol
Appearance Solid
Solubility In Water Moderate
Pka Value For the sulfonic acid group around 0 - 1, for phenolic -OH around 9 - 10 (approximate values)
Uv Vis Absorption Absorbs in the ultraviolet region, specific wavelengths related to quinoline structure
Reactivity Can react with bases due to acidic groups, can participate in electrophilic substitution reactions on the quinoline ring
Stability Stable under normal conditions but may decompose under extreme heat or in contact with strong oxidizing agents
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General Information
Frequently Asked Questions
8 - HYDROXY - 5 - QUINOLINESULFONIC ACID
8-Hydroxy-5-quinoline sulfonic acid has a wide range of uses and is used in many fields.
In the field of chemical analysis, it is often used as an analytical reagent for metal ions. Because of its special structure, it can react specifically with a variety of metal ions to generate complexes with specific colors or properties, so that the content and types of metal ions can be accurately determined. For example, in water quality testing, trace metal elements can be detected in water, which helps to determine the quality of water, which is of great significance to ensure the quality of water.
In the field of pharmaceutical chemistry, it is also of great value. Some drugs developed on the basis of 8-hydroxy-5-quinolinesulfonic acid have pharmacological activities such as antibacterial and antiviral. Or because the structure can combine with specific targets in the body of bacteria or viruses and interfere with their normal physiological activities, thus exerting therapeutic effects and providing an important direction for pharmaceutical research and development.
In the field of materials science, this compound can be used to prepare functional materials. Because of its unique physical and chemical properties, it can impart materials such as fluorescent properties. For example, in the preparation of fluorescent materials, the addition of 8-hydroxy-5-quinolinesulfonic acid can make the material fluoresce at a specific wavelength, which is very useful in optical display, biological imaging, etc.
In summary, 8-hydroxy-5-quinoline sulfonic acid is an indispensable and important substance in many fields such as analytical chemistry, drug research and development, and material preparation, and has made great contributions to the development of related fields.
8 - HYDROXY - 5 - QUINOLINESULFONIC ACID
8-Hydroxy-5-quinolinesulfonic acid is one of the organic compounds. Its physical properties are quite unique and are often concerned by researchers in the field of chemistry.
When it comes to appearance, 8-hydroxy-5-quinolinesulfonic acid is mostly crystalline, with a fine texture and often appears colorless or slightly colored. The melting point of this compound is particularly important. After many experiments, its melting point is within a certain temperature range. This property is a key basis for identifying and purifying the substance.
Furthermore, solubility is also one of its important physical properties. In water, 8-hydroxy-5-quinolinesulfonic acid exhibits a specific solubility, either soluble or slightly soluble, which is closely related to the polar groups in the molecular structure. In organic solvents, such as ethanol and acetone, the solubility status varies, or due to the interaction between the solvent and the solute.
Its density also has a specific value, although it is not often well known to the general public. However, in chemical production and fine chemical experiments, this parameter is related to the process and results of many reactions.
In addition, 8-hydroxy-5-quinolinesulfonic acid may have a specific refractive index in solution, which reflects its effect on light propagation and is also an important aspect to characterize its physical properties.
Overall, the physical properties of 8-hydroxy-5-quinolinesulfonic acid are diverse, and each property is interrelated. It is of great significance in many fields such as chemical synthesis, analysis and testing. Researchers need to explore in detail in order to make good use of this compound and contribute to the development of the chemical industry.
8 - HYDROXY - 5 - QUINOLINESULFONIC ACID
The chemical properties of 8-hydroxy-5-quinoline sulfonic acid are quite specific. This substance is acidic, and because it contains a sulfonic acid group, it can dissociate hydrogen ions in water, so it has acidic characteristics and can neutralize with alkali substances to generate corresponding salts and water.
And its hydroxyl group is also active and can participate in many chemical reactions. If under appropriate conditions, the hydroxyl group can undergo a substitution reaction and interact with nucleophiles such as halogenated hydrocarbons, so that the hydroxyl group is replaced by other groups. At the same time, the hydroxyl group can also participate in the esterification reaction and react with organic acids or inorganic acid anhydrides to form ester compounds.
Furthermore, the quinoline ring in the molecule endows it with a certain conjugated system. This conjugated structure makes the molecule stable and affects its spectral properties. In the ultraviolet-visible spectrum, the presence of the conjugated system will present a specific absorption peak, which can be used for qualitative and quantitative analysis.
In addition, 8-hydroxy-5-quinoline sulfonic acid may also exhibit coordination ability. The nitrogen atom and the hydroxyl oxygen atom on the quinoline ring may be used as coordination atoms to form complexes with metal ions. This coordination property may have potential applications in many fields, such as catalysis, materials science, etc. The complexes formed with metal ions may be different from the original compounds in structure and properties, presenting unique physical and chemical properties.
8 - HYDROXY - 5 - QUINOLINESULFONIC ACID
The synthesis method of 8-hydroxy-5-quinoline sulfonic acid has been known for a long time. In the past, this synthesis followed the traditional method, which was complicated and time-consuming.
One method is to introduce the hydroxyl group into the quinoline group through a specific reaction, and then introduce the sulfonic acid group. Initially, the quinoline is placed in a specific reaction vessel, and an appropriate amount of reactants and catalysts are added. Under a specific temperature and pressure, the hydroxyl group is smoothly connected to the quinoline ring. This process requires fine control of the reaction conditions. If there is a slight difference, the product will be impure. After the hydroxyl group is successfully introduced, the sulfonic acid group is cleverly used to connect the sulfonic acid group under a suitable environment, so as to obtain the target product 8-hydroxy-5-quinoline sulfonic acid.
Another method is to cleverly design the reaction route, using other related compounds as starting materials, and gradually construct the desired molecular structure through multi-step transformation. First, the starting material is converted into a specific functional group, so that it has an activity check point that is compatible with the subsequent reaction. Then through a series of condensation and substitution reactions, the basic structure of 8-hydroxy-5-quinoline sulfonic acid is gradually established. Each step of the reaction requires precise control of the reaction process and conditions to ensure the purity and yield of the product in each step. Finally, through appropriate separation and purification methods, pure 8-hydroxy-5-quinolinesulfonic acid is obtained.
Both of these are common methods for synthesizing 8-hydroxy-5-quinolinesulfonic acid, and each has its own advantages and disadvantages. It is necessary to choose carefully according to the actual situation.
8 - HYDROXY - 5 - QUINOLINESULFONIC ACID
8-Hydroxy-5-quinoline sulfonic acid should be avoided when using it, and attention should be paid to it in detail.
This medicine has unique properties, and you need to be cautious when touching it and smelling it. It may be irritating. If it is inadvertently in contact with the skin and eyes, rinse it with a lot of water quickly, and seek medical attention as appropriate. As the "Tiangong Kaiwu" says, "Everything has its own characteristics, use it according to its own characteristics, and only when you know the characteristics of this thing can you avoid harm and seek benefits.
In the place of use, it must be well ventilated to prevent the accumulation of harmful gases. Like a construction workshop, it is necessary to open and breathe, so that the turbid air can be dispersed. If it is used in a closed place, the gas will be trapped, or it will cause discomfort, or even harm health.
Furthermore, storage is also the key. It should be placed in a cool, dry place, away from fire and heat sources. Just like hiding objects in a warehouse with suitable temperature and humidity, it can keep its quality stable. It may be flammable and easy to deteriorate, and it should be stored improperly, fearing disasters.
When using, measure accurately, and must not be increased or decreased at will. Follow the rules, such as artisan equipment, size and measurement, and pay attention to it. Excessive use may cause adverse reactions; if the dosage is insufficient, it will be difficult to achieve the expected effect.
For those who operate, protective equipment is indispensable. Wear protective clothing, gloves and goggles, like armor, to protect yourself. In this way, you can reduce the risk of contact and keep yourself safe.