8-HYDROXY-1,1,7,7-TETRAMETHYL-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE-9-CARBOXALDEHYDE

This is the chemical name of 8-hydroxy-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H, 5H-pyridino [3,2,1-ij] quinoline-9-formaldehyde. Its chemical structure is described as follows:
The molecular structure contains a unique fused heterocyclic system. The structure of pyridino [3,2,1-ij] quinoline is formed by fusing the pyridine ring with the quinoline ring. The pyridine ring is a six-membered nitrogen-containing heterocyclic ring and is aromatic; the quinoline ring is formed by fusing the benzene ring with the pyridine ring. In the parent structure of pyridino [3,2,1-ij] quinoline, there are substituents modified at specific positions. At the 8th position, there is a hydroxyl group (-OH), which has a certain reactivity and can participate in many chemical reactions, such as esterification and etherification reactions. The 1,1,7,7 positions are all connected with methyl groups (-CH 🥰). The introduction of methyl groups can change the spatial structure and electron cloud distribution of the molecule, and affect the physical and chemical properties of the molecule. The 2,3,6,7 positions are tetrahydro states, that is, at these positions, the double bond is hydrogenated and reduced to a single bond, resulting in a decrease in the degree of unsaturation of the molecule and a change in its stability. The 9-position is connected with an aldehyde group (-CHO). The aldehyde group is a highly reactive functional group, which can undergo various reactions such as oxidation, reduction, nucleophilic addition, etc., such as reacting with alcohols to form acetals and reacting with amines to form Schiff bases.
Such a structure endows the compound with specific physical and chemical properties, and may have potential application value in organic synthesis, pharmaceutical chemistry and other fields. It can be used as an intermediate in organic synthesis to construct more complex organic molecular structures through the reaction of aldehyde groups, hydroxyl groups and other functional groups. In the field of medicinal chemistry, or due to special structures and active functional groups, it shows specific biological activities, such as antibacterial, anti-inflammatory and other biological activities, which are worthy of further study and exploration.

8 - HYDROXY - 1,1,7,7 - TETRAMETHYL - 2,3,6,7 - TETRAHYDRO - 1H, 5H - PYRIDO [3,2,1 - IJ] QUINOLINE - 9 - CARBOXALDEHYDE is an organic compound with a wide range of uses. In the field of pharmaceutical research and development, this compound may be used as a key intermediate to create drugs with specific biological activities. Due to its unique chemical structure, it may be able to combine with specific targets in organisms, and then exhibit many pharmacological activities such as antibacterial, anti-inflammatory, anti-tumor, etc., providing an important cornerstone for the development of new drugs.
In the field of materials science, it also has potential applications. For example, it can be introduced into polymer materials by specific means to endow the material with special optical, electrical or thermal properties. Due to the structural characteristics of the compound itself, or the ability to construct a special microstructure inside the material, the material presents unique advantages in photoluminescence, electrical conductivity and other aspects, opening up new paths for the preparation of new functional materials.
Furthermore, in the field of chemical research, as an organic molecule with a special structure, it can become an important research object in organic synthetic chemistry. Chemists can deeply understand the relevant reaction mechanisms and laws by exploring various chemical reactions, such as nucleophilic addition, oxidation and reduction, etc., expand the methodology of organic synthesis, and provide theoretical and practical basis for the synthesis of more complex organic compounds. This compound has important uses in fields such as medicine, materials, and chemical research, and is a key to opening the door to new exploration in many scientific fields.

8 - HYDROXY - 1,1,7,7 - TETRAMETHYL - 2,3,6,7 - TETRAHYDRO - 1H, 5H - PYRIDO [3,2,1 - IJ] QUINOLINE - 9 - CARBOXALDEHYDE, this is an organic compound whose physical properties are particularly important for its application in various fields.
Looking at its properties, it may be in a solid state at room temperature and pressure. Its melting point may be within a specific range, due to factors such as intermolecular forces and structural regularity. The exact value of the melting point needs to be determined by precise experiments. However, the interaction of various groups in its structure can be inferred that its melting point should be similar to that of similar groups with similar structures.
Solubility is also a key physical property. In organic solvents, due to the principle of similar miscibility, this compound or in polar organic solvents, such as ethanol, acetone, etc., has a certain solubility. Its molecules contain polar groups such as hydroxyl groups and aldehyde groups, which can interact with polar solvent molecules to form hydrogen bonds, etc., to help them dissolve. However, in non-polar solvents, such as n-hexane, benzene, etc., the solubility may be poor. Although there are non-polar parts such as methyl groups in the structure, the overall polarity is still strong and the interaction with non-polar solvents is weak.
As for the density, its density can be estimated according to its molecular composition and relative molecular mass. Compared with water, its density may vary depending on the type, number and arrangement of atoms in the molecule. If the intermolecular arrangement is close and the relative molecular mass is large, the density may be greater than that of water; conversely, it may be less than that of water.
In addition, the volatility of this compound also needs to be considered. Due to the intra-molecular force and group characteristics, its volatility may not be high. Hydroxyl groups, aldehyde groups, etc. can form intermolecular hydrogen bonds, enhance the intermolecular force, and make it less volatile.
The physical properties of this compound are complex and interrelated. In-depth study of its properties can provide a solid basis for its synthesis, separation, and application.

To prepare 8-hydroxy-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H, 5H-pyridino [3,2,1-ij] quinoline-9-formaldehyde, the method is as follows.
First take an appropriate amount of 1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H, 5H-pyridino [3,2,1-ij] quinoline as the starting material and place it in a clean reactor. Dissolve it in an appropriate amount with an organic solvent such as dichloromethane or N, N-dimethylformamide to fully disperse the raw materials.
Next, cool the reaction system to a suitable low temperature, such as about 0 ° C. Slowly add a solution containing hydroxylating reagents, such as a mixture containing an appropriate amount of alkali metal hydroxide (such as sodium hydroxide, potassium hydroxide) and a specific hydroxylating auxiliary agent. The dropwise addition process needs to be careful to maintain the reaction temperature stable and do not make the temperature fluctuate greatly to prevent side reactions from breeding. After the dropwise addition of the hydroxylating reagents is completed, maintain a low temperature stirring for several hours to allow the hydroxylation reaction to proceed fully. At this stage, the reaction process needs to be closely monitored, which can be observed by thin-layer chromatography and other methods. < Br >
When the hydroxylation reaction reaches the expected level, the reaction system is heated to room temperature, and then an appropriate amount of formaldehyde reagent, such as paraformaldehyde or formaldehyde aqueous solution, is added, and an appropriate amount of acid catalyst, such as p-toluenesulfonic acid or hydrochloric acid, is added. Heat up to a moderate temperature, such as 50-60 ° C, so that the formaldehyde reaction occurs. This reaction process also needs to be carefully controlled and stirred evenly to ensure that the reactants are fully in contact with the reaction.
After the reaction is completed, the product is treated by conventional separation and purification methods. First, the organic phase is extracted with an organic solvent, and then the water is removed with a desiccant such as anhydrous sodium sulfate. Next, the organic solvent is removed by vacuum distillation to obtain a crude product. After refining by column chromatography or recrystallization, a suitable eluent or solvent is selected, such as the mixed solvent of petroleum ether and ethyl acetate for column chromatography, ethanol or methanol for recrystallization, careful operation, and finally a pure 8-hydroxy-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H, 5H-pyridino [3,2,1-ij] quinoline-9-formaldehyde product. The whole process requires strict compliance with operating procedures and attention to safety to ensure the smooth progress of the reaction.

In view of this 8 - HYDROXY - 1,1,7,7 - TETRAMETHYL - 2,3,6,7 - TETRAHYDRO - 1H, 5H - PYRIDO [3,2,1 - IJ] QUINOLINE - 9 - CARBOXALDEHYDE, is a complex organic compound. However, its price in the market is difficult to determine. The price of this compound is affected by various factors.
First, the production is difficult. If the synthesis process is difficult, rare raw materials and harsh conditions are required, the price will be high. Because its preparation requires exquisite steps and superb skills, human and material resources are expensive.
Second, the supply and demand of the market. If the demand for this product is wide in scientific research, industry and other fields, but the supply is limited, the price will also rise. On the contrary, if the demand is weak and the supply is sufficient, the price may become more affordable.
Third, the level of purity. For high purity, due to the need for more refined purification processes, the cost increases, and the price is higher than that of low purity.
Fourth, the region of origin. Different origins, due to differences in raw material costs, transportation costs, policies and regulations, the price is also different.
In the current market, it is difficult to determine the price without detailed investigation of conclusive data. Or you need to consult the chemical raw material trading platform and professional chemical suppliers in detail to get its approximate price. And the market conditions are fickle, and the price also shifts over time. Therefore, to know its accurate price, it is advisable to consult relevant industry personnel or platforms in real time.