8-Bromo-5,6-difluoro-2-methyl-quinoline

8-Bromo-5,6-difluoro-2-methylquinoline is a kind of organic compound. Its main use involves the field of organic synthesis.
In pharmaceutical chemistry, such compounds may be key intermediates. Due to the structure of quinoline, it has unique biological activities. In the creation of new drugs, 8-bromo-5,6-difluoro-2-methylquinoline can be chemically modified with different functional groups to derive substances with specific pharmacological activities, or can be used to fight diseases, such as the development of new drugs for anti-cancer, antibacterial and antiviral.
In the field of materials science, it also has its uses. The development of organic electronic materials is in the ascendant. Fluorine-containing and bromine-containing quinoline derivatives, or due to their special electronic properties, are used as building units in the preparation of organic Light Emitting Diodes (OLEDs), organic field-effect transistors (OFETs) and other materials to optimize the photoelectric properties of materials and improve the efficiency and stability of devices.
Furthermore, in the field of pesticide chemistry, this compound may become the basis for the development of new pesticides. Because of its structure, it can endow molecules with specific biological activities, or it can create high-efficiency, low-toxicity and environmentally friendly pesticide products for specific pests and pathogens, which can help agricultural pest control.
Overall, although 8-bromo-5,6-difluoro-2-methylquinoline is an organic compound, it has considerable application potential in many fields such as medicine, materials, and pesticides, and can provide an important chemical basis for technological innovation and product creation in various fields.

8-Bromo-5,6-difluoro-2-methylquinoline is an organic compound with a wide range of uses in the field of chemistry. Its physical properties are crucial to the application and characteristics of this compound.
Looking at its properties, 8-bromo-5,6-difluoro-2-methylquinoline often takes a solid form at room temperature and pressure. This form gives it a certain stability and is easy to store and transport. And its solid appearance may be crystalline, and the crystal structure is regular and orderly. This is due to specific interactions between molecules, such as van der Waals force, hydrogen bonds, etc., which make the molecules arranged in an orderly manner.
The melting point of this compound is in a specific temperature range. The exact melting point value depends on factors such as its purity. Melting point is an important physical property of a substance, and its purity can be judged by measuring the melting point. If the compound has high purity, the melting point range is narrow and close to the theoretical value; if it contains impurities, the melting point decreases and the range becomes wider. The melting point of 8-bromo-5,6-difluoro-2-methylquinoline determines its physical state transition under different temperature conditions, which is of great significance for temperature control in its synthesis, separation and application.
The boiling point is also a key property. Although the specific boiling point data needs to be determined experimentally and accurately, it can be speculated that under a specific pressure, when the temperature rises to a certain extent, the compound will change from liquid to gaseous state. The boiling point is closely related to the intermolecular force. The presence of bromine, fluorine and other atoms in 8-bromo-5,6-difluoro-2-methylquinoline molecules enhances the intermolecular force, resulting in a relatively high boiling point. This means that when heating the compound to gasify it, higher energy is required.
In terms of solubility, 8-bromo-5,6-difluoro-2-methylquinoline may have different solubility in organic solvents. Because it contains aromatic rings and halogen atoms, it has certain hydrophobicity and low solubility in polar organic solvents such as water. However, in non-polar or weakly polar organic solvents, such as dichloromethane, chloroform, toluene, etc., the solubility is relatively high. This solubility characteristic is used in organic synthesis to separate and purify the compound. Taking advantage of the difference in solubility in different solvents, high-purity products are obtained by extraction, recrystallization and other operations.
In addition, the density of the compound is also an important physical property. Although the exact density value needs to be measured experimentally, it can be roughly inferred based on its molecular structure and the type and quantity of atoms contained. The relative mass of bromine atoms in the molecule will increase the overall density. Density data has practical value in the preparation of the compound solution and the calculation of the proportion of materials in the reaction system. The physical properties of 8-bromo-5,6-difluoro-2-methylquinoline are of great significance in the fields of organic synthesis and medicinal chemistry, laying the foundation for its research and application.

The chemical synthesis method of 8-bromo-5,6-difluoro-2-methylquinoline is an important topic in the field of organic synthesis. Many scholars in the past have studied this. Now, according to the ancient saying of "Tiangong Kaiwu", I will describe it in detail for you.
To synthesize this compound, the choice of starting materials is crucial. It is often based on compounds containing quinoline structure, supplemented by reagents containing bromine, fluorine and methyl. If 2-methylquinoline is used as the starting material, because the quinoline parent nucleus is already available, only bromine and fluorine atoms need to be introduced later. < Br >
When introducing bromine atoms, brominating reagents can be selected, such as N-bromosuccinimide (NBS). In a suitable solvent, such as dichloromethane, the reaction temperature and time can be controlled, and NBS can be substituted with 2-methylquinoline at a specific position to connect the bromine atoms. This reaction needs to be protected by an inert gas to prevent impurity interference and affect the purity of the bromide product.
As for the introduction of fluorine atoms, in view of the special chemical properties of fluorine, a nucleophilic substitution strategy is often used. Fluorine-containing reagents, such as potassium fluoride, can be used. First, the substrate is properly activated to make the reaction check point more active, which is conducive to the attack of fluorine ions. In a polar aprotic solvent, such as dimethyl sulfoxide (DMSO), heat and stir to cause fluorine atoms to replace other atoms in the corresponding positions to achieve the goal of 5,6-difluorine.
Throughout the synthesis, the control of the reaction conditions must be precise. Temperature, pH, and reaction time are all critical. If the temperature is too high or too low, side reactions can occur, and the purity of the product will decrease. The pH imbalance also affects the reaction process and product structure. After each step of the reaction, separation and purification techniques, such as column chromatography and recrystallization, are required to obtain high-purity intermediate products and final target products 8-bromo-5,6-difluoro-2-methylquinoline. In this way, you can achieve success.

I have not obtained the exact price range of 8 - Bromo - 5,6 - difluoro - 2 - methyl - quinoline in the market. However, if you want to know the price of this product, you can explore it from various ways.
First, if you find it on the chemical raw material trading platform. Nowadays, there are many chemical e-commerce platforms, which gather many suppliers, and they often list the price of various chemicals. Log in to such platforms to search by precise product name, or you can get the quotation of this compound under different manufacturers, different purity and packaging specifications, and then know its price range.
Second, ask the chemical product distributor. They have been involved in the chemical industry for a long time, have dealings with many manufacturers, and are familiar with various product markets. You can call or interview a professional chemical distributor to describe the characteristics of the desired compound. They should give an approximate price range according to their own resources and market conditions.
Third, refer to academic research literature and relevant industry reports. Some literature or industry reports may involve information on specific chemicals or their market prices. Although they may not be accurate in real time, they can be used as a reference for price trends and general ranges.
I regret that I have not seen the specific price of this compound in the market, but according to the above methods, I must be able to get 8-Bromo-5,6-difluoro-2-methyl-quinoline in the market price range.

8 - Bromo - 5,6 - difluoro - 2 - methyl - quinoline is an organic compound that is widely used in the fields of pharmaceutical chemistry and materials science. As for the manufacturer, many chemical reagent companies are involved.
Looking back in the past, such as Sigma - Aldrich, a well-known company in the field of chemical reagents, known for providing a wide variety of high-quality chemicals, it is very likely to produce this substance. It occupies an important position in the global chemical reagent market, and the reagents produced are widely used in scientific research institutions, university laboratories and industrial production.
TCI (Tokyo Chemical Industry Co., Ltd.) cannot be ignored either. The company focuses on the research and development and production of fine chemicals, and has a lot of exposure to novel and special-structured organic compounds. 8-Bromo-5,6-difluoro-2-methyl-quinoline may be in its product range.
Domestic Buringway Technology Co., Ltd., as an important force in chemical supply, actively expands its product range, strives to meet the diverse needs of scientific research and industrial customers, and may also be involved in the production and sales of this compound.
However, the chemical industry is developing with each passing day, and new manufacturers may also produce it. To know the exact manufacturer, check the chemical product catalog, industry information, or directly consult the relevant chemical trading platform for the latest and accurate information.