8 Aminoquinoline 7 Carbaldehyde
quinoline thiophene imidazole thiazole

8-aminoquinoline-7-carbaldehyde

Taiy Chemical

    Specifications

    HS Code

    230971

    Chemical Formula C10H8N2O
    Molar Mass 172.18 g/mol
    Appearance Solid (predicted from similar compounds)
    Solubility In Water Low (due to non - polar heterocyclic ring, may be less than 1 g/L)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, ethyl acetate
    Odor May have a pungent or characteristic aldehyde - like odor
    Stability Sensitive to air oxidation (aldehyde group can be oxidized to carboxylic acid)

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    General Information
    Where to Buy 8-aminoquinoline-7-carbaldehyde in China?
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    Frequently Asked Questions

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    What is the chemistry of 8-aminoquinoline-7-carbaldehyde?
    8-Aminoquinoline-7-formaldehyde is also an organic compound. Its molecule has a unique structure, consisting of a quinoline ring system as a group, an amino group at 8 position, and an aldehyde group at 7 position. This structure endows it with various chemical properties.
    In terms of reactivity, aldehyde groups are active functional groups and can participate in many reactions. It can perform oxidation reactions. In case of suitable oxidants, aldehyde groups can be converted into carboxylic groups to give 8-aminoquinoline-7-carboxylic acids. This carboxylic acid may have different properties and uses, and may have applications in drug synthesis, material preparation and other fields.
    At the same time, the aldehyde group can be condensed with compounds containing active hydrogen, such as alcohols, to form an acetal structure. This reaction is often used in organic synthesis to protect the aldehyde group from being affected in subsequent reactions. After the desired reaction is completed, the aldehyde group can be restored by deprotection under appropriate conditions.
    Amino groups are also active. They are basic and can react with acids to form salts. And amino groups can participate in nucleophilic substitution reactions, interact with electrophilic reagents such as halogenated hydrocarbons, and introduce new substituents in the quinoline ring to expand the structure and function of the compound.
    In addition, the conjugate system of 8-aminoquinoline-7-formaldehyde affects its spectral properties. Due to conjugation, it may have characteristic absorption in the ultraviolet-visible region, which can be used for qualitative and quantitative analysis to help researchers identify and determine the content of the compound in the mixture.
    It is rich in chemical properties and has potential application value in many fields such as organic synthesis, medicinal chemistry, and materials science. It can be used as a key intermediate to derive various compounds with specific functions.
    What are the common synthetic methods of 8-aminoquinoline-7-carbaldehyde?
    The common methods for the synthesis of 8-aminoquinoline-7-formaldehyde are as follows.
    One is to use quinoline compounds as the starting material and prepare it through multi-step reaction. For example, quinoline is first substituted at a specific position, a suitable functional group is introduced, and then the target structure is gradually constructed through oxidation, amination and other reactions. Taking a common synthesis path as an example, a halogen atom is introduced at a specific position of quinoline first, and then a nucleophilic substitution reaction is carried out to replace the halogen atom with an amino-containing reagent, and then an aldehyde group is introduced at another position through a suitable oxidation method. This process requires precise control of the reaction conditions, and the reaction conditions of each step are quite different. For example, the reaction temperature, the type and amount of halogenating agent need to be considered in the halogenation reaction; for the nucleophilic substitution reaction, the solvent selection, the type and amount of base should be paid attention to to to ensure the smooth progress of the reaction and few side reactions.
    Second, the quinoline skeleton can be constructed by cyclization from simple aromatics, and then the amino group and aldehyde group can be introduced. For example, a specific aniline derivative and a carbonyl-containing compound are cyclized and condensed under the action of an appropriate catalyst to form a quinoline ring. Subsequently, the amino group is introduced by a suitable amination reagent, and the aldehyde group is obtained by selective oxidation or other aldehyde group introduction methods. The starting materials of this method are relatively simple and easy to obtain, but the cyclization reaction step is very important, and suitable catalysts and reaction conditions need to be selected to ensure the regional selectivity and yield of cyclization. The choice of catalyst will greatly affect the efficiency and selectivity of the cyclization reaction. Different catalysts may lead to different cyclization check points and affect the structure of the final product.
    Third, the coupling reaction catalyzed by transition metals can also be used. The coupling reaction occurs under the catalysis of transition metal catalysts such as palladium and copper. This method has the advantages of relatively mild reaction conditions and good selectivity. However, the price of transition metal catalysts is higher, and the reaction system is more sensitive to impurities, so the reaction environment needs to be strictly controlled. At the same time, the selection of ligands is also very critical. After different ligands are combined with metal catalysts, the reaction activity and selectivity are significantly affected.
    8-aminoquinoline-7-carbaldehyde in what areas?
    8-Aminoquinoline-7-formaldehyde is useful in various fields such as medicine and materials.
    In the field of medicine, it can be a key intermediate for the synthesis of many drugs. With its unique structure, it can be chemically modified to obtain compounds with specific biological activities. Or it has antibacterial and antiviral effects, can act on specific targets of pathogens, interfere with their metabolism or reproduction process, and achieve the purpose of treating diseases. Or in the development of anti-tumor drugs, it interacts with specific molecules of tumor cells to inhibit the growth and spread of tumor cells.
    In the field of materials, it is also quite useful. Can participate in the preparation of functional materials, such as fluorescent materials. Because of its molecular structure, or can emit fluorescence under specific conditions, it can be used in biological imaging. It can label biomolecules to help researchers observe the behavior and distribution of molecules in organisms, providing a powerful tool for life science research. And in terms of photoelectric materials, it may affect the electronic transport and optical properties of materials, laying the foundation for the development of new photoelectric devices.
    Furthermore, in organic synthetic chemistry, 8-aminoquinoline-7-formaldehyde can participate in a variety of classic organic reactions, such as condensation reactions, nucleophilic addition reactions, etc. With this, chemists can construct more complex organic molecular structures and expand the variety and application range of organic compounds.
    What is the market price of 8-aminoquinoline-7-carbaldehyde?
    8-Aminoquinoline-7-formaldehyde is an important compound in organic chemistry. However, its market price is difficult to sum up, and it is affected by many factors.
    The first to bear the brunt is the difficulty of preparation. The synthesis path of this compound may be complicated and special reagents and conditions are required. If the preparation process is complicated and the technical and equipment requirements are quite high, the production cost will increase, and the market price will also rise.
    Furthermore, the relationship between supply and demand is also the key. If the market demand for this product is strong and the supply is limited, the merchant will raise the price because of its scarcity; conversely, if the demand is low and the supply is sufficient, the price will tend to fall.
    The price fluctuation of raw materials also affects its market pricing. If the price of raw materials required for the preparation of 8-aminoquinoline-7-formaldehyde rises, the cost of the product will also increase, and the merchant will raise the price to ensure profits.
    In addition, the purity and quality of the product have a huge impact on the price. High purity and high quality are difficult to produce and often expensive; while those with lower purity may be relatively close to the people.
    Market competition also affects its price. If there are many market participants and the competition is fierce, the merchants may reduce the price and promote in order to seize the share; if the market is almost monopolized, the price is mostly controlled by the monopolist.
    Therefore, in order to know the exact market price of 8-aminoquinoline-7-formaldehyde, it is necessary to carefully examine the preparation process, supply and demand, raw materials, quality and competition, and comprehensively weigh and balance to obtain a more accurate conclusion.
    What are 8-aminoquinoline-7-carbaldehyde storage conditions?
    8-Aminoquinoline-7-formaldehyde is a chemical substance, and its storage conditions are crucial, which is related to the stability and quality of this substance.
    This substance should be stored in a cool, dry and well-ventilated place. Because it is sensitive to humidity, humid environments are prone to deterioration, so it is necessary to keep dry. Excessive temperature can also accelerate chemical reactions, causing decomposition or other adverse changes. A cool environment can slow down the rate of such reactions.
    Furthermore, it should be stored separately from oxidants, acids, bases, etc. The chemical properties of 8-aminoquinoline-7-formaldehyde determine that when it comes into contact with these substances, it may undergo violent chemical reactions, causing danger.
    The storage place should be equipped with corresponding fire and leakage emergency treatment equipment. In case of leakage or fire and other accidents, it can be responded to in time to reduce hazards. At the same time, the storage area should be clearly marked to indicate what is stored and related hazards and precautions, so that everyone who comes into contact with it can know the risk.
    During the storage process, it should also be regularly checked whether the packaging is in good condition. If the packaging is damaged, air, moisture, etc. are easy to invade, affecting the quality of the material. If packaging problems are found, they need to be dealt with in time, or the packaging should be replaced to ensure safe storage. In this way, 8-aminoquinoline-7-formaldehyde can be properly preserved so that it can play its due effectiveness when used.