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What is the chemical structure of 8- {[5- (4-methylphenyl) thieno [2,3-d] pyrimidin-4-yl] oxy} quinoline?
This is the name of an organic compound. To clarify its chemical structure, it is necessary to analyze it according to the naming rules. This name "8- {[5- (4-methylphenyl) thieno [2,3-d] pyrimidine-4-yl] oxy} quinoline" can be disassembled in several parts to explore its structure.
"Quinoline" is a basic parent nucleus with a specific cyclic structure, formed by fusing a benzene ring with a pyridine ring. " 8 - {[5- (4-methylphenyl) thiopheno [2,3-d] pyrimidine-4-yl] oxy} "This part is the 8-position substituent of the quinoline parent nucleus.
Where," [5- (4-methylphenyl) thiopheno [2,3-d] pyrimidine-4-yl] oxy "can be subdivided." Thiopheno [2,3-d] pyrimidine "is another fused ring structure, which is fused by a thiophene ring and a pyrimidine ring in a specific manner." 5- (4-methylphenyl) "indicates that there is a 4-methylphenyl group attached to the 5th position of the thiophenopyrimidine ring, and the 4-methylphenyl group has a methyl substitution at the 4th position of the benzene ring." 4-yl "refers to the 4-position of the thiophenopyrimidine ring connected to the oxygen atom, which is then connected to the 8-position of the quinoline.
In this way, the chemical structure of this compound is based on quinoline as the parent nucleus, and the 8-position is connected to the thiophenopyrimidine structure containing 4-methylphenyl substitution by the oxygen atom. The parts are connected according to specific rules to form the unique chemical structure of this
What are the physical properties of 8- {[5- (4-methylphenyl) thieno [2,3-d] pyrimidin-4-yl] oxy} quinoline?
8- {[5- (4-methylphenyl) thiopheno [2,3-d] pyrimidine-4-yl] oxy} quinoline is an organic compound, its physical properties are very critical, and it is of great significance in chemical research and application fields.
Looking at its appearance, this compound is often in solid form due to strong intermolecular forces and orderly arrangement of molecules. Its color is mostly white or off-white, which is due to the absorption and reflection characteristics of the molecular structure to visible light. The chemical bonds and electronic transitions in the molecule determine the absorption of specific wavelengths of light, so that the rest of the visible light is reflected white or off-white. < Br >
When it comes to melting point, the compound has a certain melting point range, which is closely related to the intermolecular forces. Intermolecular forces such as van der Waals forces and hydrogen bonds require specific energy to overcome, causing the lattice structure to disintegrate and realizing the transition from solid to liquid. The exact melting point value is of great significance for the determination of the purity of the compound. The melting point range of high-purity compounds is narrow. If it contains impurities, the melting point decreases and the range becomes wider.
In terms of solubility, the dissolution of this compound in organic solvents varies. In general, it has good solubility in polar organic solvents such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), because these solvents can form strong interactions with compound molecules, such as hydrogen bonds and dipole-dipole interactions, which help molecules disperse in solvents. However, in non-polar organic solvents such as n-hexane and toluene, the solubility is poor, because the interaction between non-polar solvents and polar compounds is weak. The solubility in water is also poor, because the molecular polarity is not enough to form an effective interaction with water molecules, and the hydrophobic group affects its dispersion in water.
In addition, the physical properties such as the density and boiling point of the compound are also determined by the molecular structure and intermolecular forces. The density reflects the mass of the substance per unit volume and is related to the molecular weight and the way of molecular accumulation; the boiling point is related to the magnitude of the intermolecular force. The stronger the force, the higher the boiling point.
What is the synthesis method of 8- {[5- (4-methylphenyl) thieno [2,3-d] pyrimidin-4-yl] oxy} quinoline?
To prepare 8- {[5- (4-methylphenyl) thiopheno [2,3-d] pyrimidine-4-yl] oxy} quinoline, the method is as follows:
First take an appropriate amount of 4-hydroxyquinoline, place it in a clean reactor, dissolve it with an appropriate amount of organic solvent, such as dimethylformamide, stir well to form a homogeneous phase. Then slowly add a base, such as potassium carbonate, to activate the hydroxyl group. The amount of base needs to be accurately measured to ensure a smooth reaction. < Br > Take another 5- (4-methylphenyl) thiopheno [2,3-d] pyrimidine-4-halide, which can be a chloride or a bromide. Dissolve it in an organic solvent and add it dropwise to the above reaction system containing 4-hydroxyquinoline. When adding dropwise, pay close attention to the reaction temperature, which should be maintained in a moderate range, usually between 50-80 degrees Celsius, to ensure the steady progress of the reaction and prevent side reactions from occurring.
After adding dropwise, continue to stir the reaction mixture for several hours until the reaction is complete. In this process, the reaction process can be monitored by thin-layer chromatography to confirm the consumption of raw materials and the formation of products.
When the reaction is over, the reaction solution is cooled to room temperature, and then poured into an appropriate amount of ice water to precipitate the product. The precipitated solids are collected by suction filtration and washed alternately with water and organic solvents to remove impurities. The obtained crude product is recrystallized and purified. A suitable solvent is selected, such as a mixed solvent of ethanol and water. Careful operation results in a pure 8- {[5- (4-methylphenyl) thiopheno [2,3-d] pyrimidine-4-yl] oxy} quinoline. The whole synthesis process requires strict compliance with the operating procedures and attention to detail to obtain the ideal product.
In what fields is 8- {[5- (4-methylphenyl) thieno [2,3-d] pyrimidin-4-yl] oxy} quinoline used?
8 - {[5 - (4 - methylphenyl) thieno [2,3 - d] pyrimidin - 4 - yl] oxy} quinoline, which is an organic compound. It has applications in many fields, and the following is a detailed description of Jun.
In the field of medicine, such compounds containing heterocyclic structures often have unique biological activities. They may serve as potential drug lead compounds, and after in-depth research and optimization, they are expected to be developed into drugs for the treatment of specific diseases. For example, some heterocyclic compounds have inhibitory effects on the growth and proliferation of tumor cells, and may play a role in the development of anti-cancer drugs; they may also have regulatory effects on certain inflammation-related pathways, so as to be used in the creation of anti-inflammatory drugs.
In the field of materials science, this compound may have made a name for itself in organic optoelectronic materials due to its special structure. Or it can be used to prepare organic Light Emitting Diode (OLED) materials, because its structure can affect the electron transport and luminescence properties of molecules, endowing the material with unique optoelectronic properties, so that the prepared OLED devices have better luminous efficiency and stability.
In the field of agriculture, some compounds with similar structures can exhibit certain biological activities, or can be developed into pesticides. Or have repellent or poisonous effects on some pests, or have inhibitory effects on plant diseases and bacteria, helping to control agricultural pests and ensure crop yield and quality.
In the field of chemical synthesis, this compound can be used as a key intermediate. Chemists can perform various chemical reactions on it, such as substitution reactions, addition reactions, etc., to prepare more complex and diverse organic compounds, expand the scope of organic synthesis, and provide an important foundation for the creation of new substances.
What is the market outlook for 8- {[5- (4-methylphenyl) thieno [2,3-d] pyrimidin-4-yl] oxy} quinoline?
8- {[5- (4-methylphenyl) thiopheno [2,3-d] pyrimidine-4-yl] oxy} quinoline is one of the organic compounds. Looking at its market prospects, we should look at it from a multi-faceted perspective.
From the field of pharmaceutical research and development, this compound may have unique biological activities and may emerge in the creation of new drugs. Nowadays, the pharmaceutical industry is eager for new specific drugs. If it shows excellent efficacy in pharmacological research, such as high selective affinity for specific disease targets, or can regulate key physiological and biochemical pathways, it will attract the attention of pharmaceutical companies and researchers, and the market prospect will be vast.
In the field of materials science, it may endow materials with novel properties due to their special structures. If it can be used in the field of optoelectronic materials to exhibit excellent optical and electrical properties, such as high photoelectric conversion efficiency and good fluorescence properties, it can be applied to new display technologies, optoelectronic devices, etc. The market in this field is booming, and the demand is increasing day by day, and its prospects are also very promising.
However, the road to market expansion is not smooth. The process of synthesizing this compound may be complicated and costly. If large-scale production is to be achieved, it is urgent to optimize the synthesis process and reduce costs. And the market competition is fierce, and similar or alternative compounds are also emerging one after another. Only in terms of performance, cost, environmental protection and other aspects can it be favored by the market.
In summary, 8- {[5- (4-methylphenyl) thieno [2,3-d] pyrimidine-4-yl] oxy} quinoline Although it has considerable market potential, it is necessary for scientific research and industry to join hands to overcome technical problems in order to sail in the market wave.