8-({4-ethyl-5-[(2-phenylethyl)sulfanyl]-4H-1,2,4-triazol-3-yl}methoxy)quinoline

8- {[4-ethyl-5- [ (2-phenethyl) thio] -4H-1,2,4-triazole-3-yl] methoxy} quinoline, this is an organic compound. According to its name, it is composed of quinoline parent nucleus, triazole ring and other substituents.
quinoline, with the structure of azanaphthalene, is an important nitrogen-containing heterocyclic compound, which is common in many drugs, natural products and functional materials. In this compound, the 8th position of quinoline is connected to a specific substituent. This substituent is connected by a methoxy group and a triazole ring. The triazole ring is a five-membered heterocyclic ring containing three nitrogen atoms, which has a unique electronic structure and reactivity. The fourth position of the triazole ring is connected with ethyl group, and the fifth position is connected with (2-phenethyl) thio group. Phenethyl contains benzene ring and ethyl group. The benzene ring has a large π bond and is conjugated, giving the compound a specific electronic effect and spatial structure. The presence of sulfur groups also affects the physical and chemical properties of the compound, such as lipophilicity and reactivity.
Such a complex chemical structure endows the compound with diverse potential properties and applications. Due to the characteristics of quinoline, triazole ring and phenethyl group, it has potential biological activities in the field of medicinal chemistry, such as antibacterial, anti-inflammatory, anti-tumor, etc.; in the field of materials science, or due to the interaction of each structural unit, it exhibits unique optical and electrical properties and can be used to develop new functional materials.

This is a rather complex organic compound, 8- ({4-ethyl-5- [ (2-phenethyl) thio] -4H-1,2,4-triazole-3-yl} methoxy) quinoline. Its physical properties are as follows:
1. ** Appearance **: Often presented in solid form, but the specific appearance varies according to its purity and crystallization, or white to light yellow powder, crystalline solid, all due to intermolecular forces and arrangements.
2. ** Melting point **: Melting point is an important physical property, which can help identify and determine purity. Unfortunately, the relevant data of this compound is limited, and the specific melting point is difficult to determine. However, the melting point of such organic compounds containing quinoline and triazole structures may be in the range of 100-300 ° C. Because the quinoline and triazole structures contain aromatic rings and heterocycles, there are strong forces between molecules, such as π-π stacking and hydrogen bonding, resulting in a higher melting point.
3. ** Solubility **: In view of its structure containing hydrophobic aromatic ring (quinoline and phenethyl moiety) and polar heterocyclic ring (triazole ring) and polar ether bond (methoxy group), in organic solvents or, in polar organic solvents such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF) has a certain solubility, and its polar part can form hydrogen bonds or dipole-dipole interactions with solvents; in non-polar organic solvents such as n-hexane, the solubility is poor, because although the hydrophobic aromatic ring part has van der Waals force action with non-polar solvents, it is not enough to overcome the intermolecular force. The solubility in water may be low, because its hydrophobic part accounts for a large proportion, which is not conducive to the formation of hydrogen bonds with water, and only polar groups are not enough to make it well soluble in water.
4. ** Density **: Density is also an important physical property, which is difficult to give accurately due to lack of experimental data. However, according to the structure containing heavy atoms (such as nitrogen and sulfur) and having a polycyclic structure, its density may be greater than that of water. The weight per unit volume is increased due to heavy atoms and compact ring structures.
5. ** Stability **: The quinoline and triazole structures in the molecule are relatively stable, and the aromatic ring conjugate system provides thermodynamic stability. However, the thio group part may be more active and easy to be oxidized. When it is left in the air for a long time or encounters an oxidizing agent, the thio group may be transformed into sulfoxide or sulfone. And under the conditions of strong acid and strong base, the ether bond or triazole ring structure may undergo reactions such as hydrolysis, resulting in structural changes and decreased stability.

To prepare 8- {[4-ethyl-5- [ (2-phenylethyl) thioalkyl] -4H-1,2,4-triazole-3-yl] methoxy} quinoline, the method is as follows:
First take a suitable reaction vessel and prepare it in a clean state. Choose quinoline as the starting material because its structure contains a quinoline skeleton of the target molecule. In the container, carefully add an appropriate amount of quinoline, with an appropriate solvent, such as dichloromethane or N, N-dimethylformamide, so that the quinoline is fully dissolved to create a homogeneous reaction environment. < Br > Another compound containing 4-ethyl-5- [ (2-phenylethyl) thioalkyl] -4H-1,2,4-triazole-3-yl structure, which is the key intermediate. According to the stoichiometric ratio, slowly add it to the solution containing quinoline, and the operation must be fine to prevent overreaction.
Then, add a specific base, such as potassium carbonate or triethylamine, which can help the reaction process, adjust the pH of the reaction system, and promote the formation of chemical bonds. Warm up to a suitable temperature, or stir at room temperature, depending on the specific reactivity. This process takes a long time, and it is necessary to stir patiently to allow the reactants to fully contact and react. During the
reaction, the progress of the reaction is closely monitored by thin layer chromatography or liquid chromatography. When the raw material is significantly reduced and the target product peak is obvious, the asymptotic end of the reaction can be determined. After the
reaction is completed, the reaction liquid is poured into an appropriate amount of ice water to stop the reaction. After extraction with an organic solvent, the organic phases are combined after multiple extractions, and dried with anhydrous sodium sulfate to remove the moisture in the organic phase.
Finally, the organic solvent was removed by reduced pressure distillation, and then the product was refined by column chromatography, and a suitable eluent was selected to separate the pure 8- {[4-ethyl-5- [ (2-phenylethyl) thioalkyl] -4H-1,2,4-triazole-3-yl] methoxy} quinoline.

8- {4-ethyl-5- [ (2-phenylethyl) thioalkyl] -4H-1,2,4-triazole-3-yl} methoxyquinoline, this compound may have unique uses in the field of medicine and chemical industry.
In the field of medicine, or can be used as active pharmaceutical ingredients. Its structure contains quinoline and triazole parts, quinoline compounds have many biological activities, such as antimalarial, antibacterial, anti-cancer, etc. Triazole structure is common in pharmaceutical chemistry, which can enhance the affinity of compounds with biological targets. The combination of the two may be effective in the treatment of specific diseases, such as anti-cancer, or can precisely act on key targets of cancer cells, inhibit proliferation and induce apoptosis; in antibacterial, or can destroy bacterial cell walls, cell membrane synthesis, interfere with metabolism and cause their death.
In the chemical industry, or as a material additive. Because of its special structure, it can enhance some properties of materials, such as in polymer materials, or improve thermal stability, so that the material does not deform or decompose at high temperature, and expands the use temperature range; or enhances the material's oxidation resistance, prevents material aging, and prolongs the service life.
Or as an organic synthesis intermediate. With its structural activity check point, other functional groups can be introduced through chemical reactions to derive a series of structurally similar compounds, which can explore new substances for drug research and development and materials science, expand the research boundary and open up new possibilities.

8- {4-Ethyl-5- [ (2-phenethyl) thio] -4H-1,2,4-triazole-3-yl} methoxyquinoline, in today's market prospects, is actually complex and diverse.
Looking at the field of medicine in which it is located, this compound can be used as a potential drug lead compound due to its unique molecular structure or specific biological activity. At present, pharmaceutical research and development is eager for new active molecules. If it can be studied in depth and demonstrate clear pharmacological effects, such as anti-tumor and antibacterial effects, it is expected to open the door to new drug development. However, the road to the development of new drugs is fraught with danger. It requires many rigorous tests, such as cell experiments, animal experiments and clinical trials, to determine its safety and effectiveness. The process takes a long time and is also costly.
In the field of materials science, if the compound has special optical, electrical or thermal properties, it may be applied to the creation of new materials. However, the research and development of materials also needs to precisely control its performance, compete with existing materials, and have outstanding advantages in order to occupy a place in the market.
Looking at the chemical industry, it may be used as an intermediate for the synthesis of more complex chemicals. However, the chemical market is highly competitive, and the price of products is determined by many factors such as raw material costs and production processes. If efficient and environmentally friendly production processes can be developed, costs can be reduced, and opportunities for development may be found in the chemical market.
Overall, 8- {4-ethyl-5- [ (2-phenethyl) thio] -4H-1,2,4-triazole-3-yl} methoxyquinoline has potential application value, but if it is to emerge in the market, it is necessary for scientific researchers and enterprises to work closely together to overcome difficulties in research and development and production in order to seize opportunities and open up broad market prospects.