As a leading 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid?
7-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, this is an organic compound. Looking at its name, it can be deduced that its structure must contain a quinoline parent nucleus.
Quinoline is a compound formed by fusing a nitrogen-containing hexamembered heterocycle with a benzene ring. In 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, the quinoline parent nucleus is in the dihydrogen state at positions 1 and 4, which means the double bond hydrogenation at positions 1 and 4.
"4-oxo" indicates that there is a carbonyl group (C = O) at the 4th position of the quinoline parent nucleus, which endows the compound with specific chemical activity and physical properties.
"7-methoxy" indicates that there is a methoxy group (-OCH) at the 7th position of the quinoline parent nucleus, and the methoxy group is the power supply group, which has a great influence on the electron cloud distribution and reactivity of the molecule.
Furthermore, "3-carboxylic acid" means that there is a carboxyl group (-COOH) at the 3rd position of the quinoline parent nucleus. The carboxyl group is acidic and can participate in many chemical reactions, such as salt formation, esterification, etc.
In summary, the chemical structure of 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is based on the quinoline parent nucleus, hydrogenated at positions 1 and 4, carbonyl at position 4, methoxy at position 7, and carboxyl at position 3. This unique structure determines its chemical properties and reactivity, and may have important uses in organic synthesis, pharmaceutical chemistry, and other fields.
What are the main uses of 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
7-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, which has a wide range of uses. In the field of medicine, it is often a key intermediate for the synthesis of many drugs. Due to its special chemical structure, it can participate in the construction of a variety of drug molecules, endowing drugs with specific physiological activities and pharmacological functions.
For example, some drugs with antibacterial and anti-inflammatory effects will use this compound in the synthesis path. With its structure and characteristics, it can be combined with other chemical groups through a series of chemical reactions to construct molecular structures that inhibit the growth and reproduction of bacteria.
In the field of organic synthetic chemistry, it is also an important basic raw material. Chemists can modify and react with various functional groups to expand the structural diversity of compounds and synthesize organic compounds with novel structures and unique functions to meet the needs of compounds with special properties in different fields.
In the field of materials science, it may also have potential uses. Through rational design and synthesis, it may be introduced into polymer materials to endow materials with special properties such as optics, electricity, and heat, providing new directions and approaches for the research and development of new materials. From this perspective, 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acids play an indispensable role in many fields, providing important material basis and technical support for the development of various fields.
What are the synthesis methods of 7-methoxy-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid
The synthesis method of 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is described in ancient books, and there are about several ends.
First, it can be originated from suitable aromatic starting materials. If an aniline compound with a specific substituent is used as the starting point, it is first reacted with a suitable carboxylic acid derivative, such as an acyl halide or an acid anhydride, under specific conditions. This reaction may require a catalytic agent, such as Lewis acid, to promote its formation. The two combine to obtain an intermediate product. This intermediate product is cyclized. When it is cyclized, it may need to be heated or assisted by a specific alkali agent to rearrange and close the chemical bonds in the molecule to form the basic skeleton of quinoline. At this time, the 4-position or the untargeted oxygenated state can be oxidized to a 4-oxo state by appropriate oxidizing reagents, such as oxides or peroxides of a high-valent metal, and the 7-position methoxy group can be introduced in appropriate steps. This introduction may be obtained by the nucleophilic substitution reaction of halogenated alkanes and phenolic hydroxyl groups.
Second, there are also modifiers based on quinoline parent compounds. To find a suitable quinoline substrate, the 3-position, 7-position may have an easily transformable substituent first, and the 4-position may be a modifiable functional group. First, the 3-position is carboxylated with an appropriate carboxylation reagent, and the carboxyl group is introduced in a suitable reaction environment, such as in a specific organic solvent, under the catalysis of a base. Then, the 7-position substituent is adjusted to a methoxy group. This process may involve the fine operation of the substitution reaction. As for the 4-position, according to the characteristics of its existing functional groups, through suitable oxidation, reduction or other transformation reactions, the final structure of the 4-oxygen generation is obtained.
Third, there is also a multi-step series reaction method. First, a variety of small molecule raw materials, such as nitrogen-containing, oxygen-containing heterocyclic small molecules and compounds with aryl groups, are used in one pot, through carefully designed reaction sequences and conditions, such as different stages of temperature regulation, pH and reagent addition sequence, to gradually build a molecular skeleton. At the same time, each substituent is introduced accurately at the appropriate time, and the construction of 7-methoxy, 4-oxo and 3-carboxylic acids is completed in sequence, resulting in the synthesis of 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acids. Each of these methods has its own advantages and disadvantages. In practice, one should choose carefully according to the availability of raw materials, the difficulty of reaction, and the high or low yield.
What are the physical and chemical properties of 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
7-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, this is an organic compound. Its physical and chemical properties are unique and may be of important value in scientific research and industrial fields.
Looking at its physical properties, under normal temperature and pressure, this compound is mostly solid or crystalline, which is arranged in an orderly manner due to intermolecular forces. Its melting point may be within a specific temperature range. This temperature is the critical value for the molecule to break free from the lattice and transform into a liquid state, which is of great significance for its separation and purification.
When it comes to solubility, according to the principle of similar miscibility, it may have a certain solubility in organic solvents such as ethanol and acetone. The molecular structure of Gein organic solvents is similar to that of this compound, which can weaken the intermolecular force of the compound and make it disperse in the solvent. However, the solubility in water may be limited, because there are many hydrophobic groups in the molecular structure, and the interaction with water molecules is weak.
In addition to chemical properties, the carboxylic group in this compound is acidic and can neutralize with bases to generate corresponding carboxylic salts and water. This reaction is commonly used in adjusting the pH of solutions and preparing derivatives. At the same time, the 4-oxo-1,4-dihydroquinoline structure part has a certain conjugate system, which makes the compound stable and can participate in a variety of nucleophilic and electrophilic reactions, which can be used to construct more complex organic molecular structures. It can be used as an important intermediate in organic synthetic chemistry. By ingeniously designing the reaction route, many compounds with biological activity or special functions can be prepared.
What is the price of 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid in the market?
What I am asking you is about the price of 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid in the market. However, the price of this chemical is difficult to determine.
The price of the cover often changes for many reasons. First, the price of the raw material is the main reason. If the raw material required to make this acid is scarce or expensive, the price of the acid will also be high. Second, the preparation method and process are complicated and simple, which also affects its price. If the preparation method is complicated, multiple processes and special conditions are required, manpower and material resources are expended, and the price will also increase.
Furthermore, the supply and demand relationship in the market also affects its price. If there are many applicants and few suppliers, the price will rise; conversely, if the supply exceeds the demand, the price will be depressed. In addition, the brand, quality level and transaction volume of the manufacturer are all related to the price. Well-known manufacturers and high-quality ones have high prices; and large purchases may get preferential prices.
From this perspective, to know the exact price of 7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, when consulting chemical raw material suppliers or chemical product trading platforms, you can get a more accurate price.