7 Chloro 4 Methoxyisoquinoline
quinoline thiophene imidazole thiazole

7-chloro-4-methoxyisoquinoline

Taiy Chemical

    Specifications

    HS Code

    391334

    Chemical Formula C10H8ClNO
    Molecular Weight 193.63
    Appearance Solid (usually)
    Physical State At Rt Solid
    Melting Point Data may vary, needs specific measurement
    Boiling Point Data may vary, needs specific measurement
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane
    Density Data may vary, needs specific measurement
    Pka Data may vary, needs specific measurement
    Flash Point Data may vary, needs specific measurement
    Odor Typically odorless or with a faint organic odor

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    General Information
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    Frequently Asked Questions

    As a leading 7-chloro-4-methoxyisoquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 7-chloro-4-methoxyisoquinoline?
    7-Alkane-4-methoxyisosquaric acid, this is a strange chemical substance with unique physical properties. At room temperature, it is a stable solid, with a white appearance like snow, a fine texture like powder, and a pure and flawless appearance.
    When it comes to the melting point, it is about a specific range. This temperature causes its lattice structure to gradually disintegrate, slowly turning from solid to liquid. When heated near the melting point, the molecular vibration intensifies, the interaction force changes, and the morphological transformation is caused. This melting point is a key indicator for the identification and purification of the substance.
    Its solubility also has characteristics, and it shows good solubility in some organic solvents, such as alcohols and ethers. Due to the specific interaction between the molecular structure and the organic solvent molecules, such as van der Waals force, hydrogen bond, etc., it is uniformly dispersed in it. However, in water, the solubility is not good, and it is difficult to dissolve due to the low matching degree between the molecular polarity and the polarity of the water molecule.
    The density of 7-alkane-4-methoxy isosquaric acid is also an important physical property. Its density depends on the molecular weight and the way of molecular accumulation. Compared with common substances, it may have unique values. This density is related to the measurement of substances and the mixing ratio in chemical production and experimental operations, and has a profound impact on the reaction process and product quality.
    In addition, the stability of this substance to light and heat also needs attention. Under moderate conditions, it can be kept stable; however, high temperature and strong light can act for a long time, or cause changes in molecular structure, causing changes in its physical and chemical properties. When storing and using, it is necessary to choose a suitable environment according to this characteristic to ensure that its properties remain unchanged and play its due role.
    What are the chemical properties of 7-chloro-4-methoxyisoquinoline?
    7-Bromo-4-methoxyisobenzofuran, which has unique physical properties and multi-terminal chemical characteristics.
    It has the properties of halogenated aromatics, and the bromine atom is active, which can involve the reaction of nucleophilic substitution. Every nucleophilic reagent, such as alkoxides and amines, bromine is easily replaced, and different derivatives are produced. If it encounters sodium alcohol, it can form corresponding ethers; if it is co-heated with amines, it can obtain nitrogen-containing derivatives, which are very important in organic synthesis and can expand the change of molecular structure.
    Because of the presence of methoxy group, it has the electron cloud effect, which can increase the electron cloud density of the benzene ring, making the benzene ring more susceptible to attack by electrophilic reagents, which can involve electrophilic substitution reactions such as halogenation, nitrification, and sulfonation. And the methoxy group has the effect of positioning the reaction check point, so that the electrophilic reagent enters the specific position of the benzene ring, which helps to accurately synthesize the target product.
    The isobenzofuran structure in the molecule has unsaturation and can involve addition reactions. In case of suitable dienes, it can be reacted by Diels-Alder to form a thick ring compound. This is a good method for constructing complex ring structures and is commonly used in the field of total synthesis of natural products.
    In addition, its stability is also related to specific reaction conditions. High temperature, strong acid or strong alkali environment, or cause structural change and decomposition. Therefore, the reaction involving this compound must carefully control the conditions, seek the best reaction effect, and obtain high-purity products.
    Its diverse chemical properties make 7-bromo-4-methoxy isobenzofuran of great value in many fields such as organic synthesis and pharmaceutical chemistry. It is an important raw material and intermediate for the creation of new compounds and the development of new drugs.
    What are the main uses of 7-chloro-4-methoxyisoquinoline?
    7-Alkane-4-methoxyisopentenal has many main uses. This is a key intermediate in organic synthesis. In the field of medicinal chemistry, it is often the cornerstone of the creation of new drugs. The preparation of many natural products and synthetic drugs depends on its participation.
    The research and development of Guanfu drugs, this compound can use its unique chemical properties to build a complex molecular structure, paving the way for the development of new drugs for the treatment of various diseases. For example, in the creation of anti-tumor drugs, it can use its activity check point to combine with specific targets of tumor cells to block the growth and proliferation pathways of tumor cells and contribute to the solution of cancer problems.
    In the field of fragrance chemistry, 7-alkane-4-methoxyisopentenal also shows extraordinary value. Because of its special aroma components, it can add a unique flavor to the fragrance formula and prepare a unique fragrance. Or fresh and elegant, or rich and mellow, it can meet the needs of different fragrance products, and enhance its aroma quality and uniqueness in perfumes, air fresheners and other products.
    Furthermore, in the field of materials science, it can participate in the synthesis process of specific materials, giving materials novel properties. For example, in the preparation of some functional polymer materials, the introduction of this compound can improve the solubility and stability of the material, expand the application range of the material, and make it play a unique role in the fields of electronics and optics.
    It can be seen that 7-alkyl-4-methoxyisovaleraldehyde plays an indispensable role in many fields, providing an important material basis and chemical support for the development of various fields.
    What are the synthesis methods of 7-chloro-4-methoxyisoquinoline?
    To prepare 7-bromo-4-methoxyisobenzaldehyde, there are three methods.
    First, start with 4-methoxybenzoic acid. First, 4-methoxybenzoic acid is co-heated with thionyl chloride to obtain 4-methoxybenzoyl chloride. Then 4-methoxybenzoyl chloride reacts with aluminum bromide and copper bromide in carbon disulfide to introduce bromine atoms to obtain 3-bromo-4-methoxybenzoyl chloride. After hydrolysis and oxidation, the target product can be obtained. This step is slightly complicated, but the raw materials are easy to obtain, and the conditions are not harsh.
    Second, 4-methoxybenzaldehyde is used as the starting material. In a suitable solvent, under the action of a catalyst such as Lewis acid, it reacts with bromine. This reaction requires precise temperature control. Because the aldehyde group of benzaldehyde is an ortho-site locator and the ortho-site resistance is affected, 3-bromo-4-methoxybenzaldehyde is mainly obtained. After that, the methoxy group is introduced into the aldehyde group through a specific reaction to obtain 7-bromo-4-methoxyisobenzaldehyde. This method is relatively simple, but the selectivity of the reaction needs to be carefully adjusted to increase the yield of the target product.
    Third, take 2-bromo-5-methoxytoluene as the starting material. First oxidize it to 2-bromo-5-methoxybenzoic acid, commonly used oxidants such as potassium permanganate, etc. Then through a series of reactions, such as converting carboxyl groups into aldehyde groups, this process may involve reduction, specific reagent action and other steps, and finally obtain 7-bromo-4-methoxyisobenzaldehyde. The choice of raw materials for this route is slightly biased, but if the operation is proper, the yield is good, and the reaction mechanism of each step is clear, which is beneficial for the optimization of the synthesis process.
    What are the precautions for storing and transporting 7-chloro-4-methoxyisoquinoline?
    7-Fluoro-4-methoxy isobenzofuran needs to pay attention to many matters during storage and transportation.
    For storage, first, it should be found in a cool and dry place. If this medicine is placed in a high temperature and humid place, it is easy to cause its chemical properties to change, or cause decomposition and deterioration, resulting in damage to its quality and efficacy. Second, it is necessary to ensure that the storage place is well ventilated. Because it may evaporate special odors or harmful gases, good ventilation can be dispersed in time to prevent accumulation and cause safety hazards, and it can also keep the air in the storage environment fresh. Third, it should be strictly stored separately from oxidants, acids, alkalis and other substances. This compound is chemically active, comes into contact with the above substances, or triggers violent chemical reactions, such as combustion, explosion and other serious accidents.
    When transporting, bear the brunt, and the packaging must be tight and stable. Appropriate packaging materials must be selected to ensure that it is not damaged by vibration or collision during transportation, and to prevent drug leakage. Second, the transportation vehicle must have a good ventilation and temperature control device. Ventilation can dissipate harmful gases that may be generated, and the temperature control can maintain a suitable temperature to avoid affecting the stability of the drug due to too high or too low temperature. Third, the transportation personnel need to be professionally trained. Familiar with the characteristics, risks and emergency treatment methods of 7-fluoro-4-methoxy isobenzofuran, in the event of an emergency, it can respond quickly and correctly. Fourth, the transportation process should strictly follow relevant regulations and standards. Conduct necessary transportation permits and procedures to ensure legal compliance of transportation, and the transportation route should avoid densely populated areas and environmentally sensitive areas to reduce the harm to the public and the environment in the event of an accident.