7 Chloro 3 Methyl 8 Quinolinecarboxylic Acid
quinoline thiophene imidazole thiazole

7-Chloro-3-methyl-8-quinolinecarboxylic acid

Taiy Chemical

    Specifications

    HS Code

    694442

    Name 7-Chloro-3-methyl-8-quinolinecarboxylic acid
    Chemical Formula C11H8ClNO2
    Molar Mass 221.64 g/mol
    Appearance Solid (usually a powder)
    Melting Point 283 - 285 °C
    Solubility In Water Poorly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO
    Pka Value Approx. 3 - 4 (carboxylic acid group)
    Odor Odorless (usually)
    Stability Stable under normal conditions
    Color Off - white to light yellow

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    General Information
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    Frequently Asked Questions

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    What is the chemistry of 7-Chloro-3-methyl-8-quinolinecarboxylic acid?
    7-Chloro-3-methyl-8-quinoline carboxylic acid, this is an organic compound with a quinoline ring in its molecular structure, and is connected to a chlorine atom at the 7th position, a methyl group at the 3rd position, and a carboxyl group at the 8th position. Its chemical properties are unique, with certain acidity, because the carboxyl group can ionize hydrogen ions under suitable conditions.
    When it comes to solubility, it has good solubility in organic solvents, such as common ethanol and acetone, but it has limited solubility in water. Due to the large proportion of hydrophobic quinoline rings in the molecule.
    7-chloro-3-methyl-8-quinoline carboxylic acid has higher chemical activity. Carboxyl groups can participate in many reactions, such as esterification with alcohols. Under the catalysis of acids or bases, carboxyl groups dehydrate and condensate with alcohol hydroxyl groups to form corresponding ester compounds. At the same time, the chlorine atoms on its quinoline ring are also reactive, and can be substituted under specific conditions and replaced by other nucleophiles, and then a variety of derivatives can be derived for the synthesis of organic materials with different functions.
    Furthermore, due to its structure containing nitrogen heterocycles, 7-chloro-3-methyl-8-quinoline carboxylic acids may exhibit certain coordination ability, which can complex with metal ions to form complexes. This property may have potential application value in the field of materials science and catalysis. Its performance in chemical reactions is determined by the molecular structure, and the interaction of various groups makes it rich in chemical properties, which is of great significance in organic synthesis and related fields.
    What are the main uses of 7-Chloro-3-methyl-8-quinolinecarboxylic acid?
    7-Chloro-3-methyl-8-quinoline carboxylic acid, this is an organic compound with a wide range of uses.
    In the field of medicine, it is often a key intermediate in the synthesis of many antibacterial drugs. Antibacterial drugs have made outstanding achievements in treating bacterial infections, which can effectively inhibit or kill bacteria and help the human body recover. With the special chemical structure of 7-chloro-3-methyl-8-quinoline carboxylic acid, it can be derived with highly effective antibacterial activity drug molecules, which can play a role in Gram-positive and Gram-negative bacteria, such as Streptococcus pneumoniae, Escherichia coli and other infections caused by related drugs can be dealt with.
    In the field of pesticides, it also has important uses. It can be used as a raw material for the synthesis of some efficient and low-toxic pesticides. Such pesticides have a good control effect on crop pests, can effectively protect crops from insect infestation, improve crop yield and quality. Its mechanism of action either interferes with the physiological and metabolic processes of pests, or affects the nervous system of pests, etc., so as to achieve the purpose of killing pests.
    In the field of materials science, 7-chloro-3-methyl-8-quinoline carboxylic acid can also play a role. It can be used to prepare materials with special properties, such as some functional polymer materials. By introducing it into the polymer structure, it can endow materials with unique optical, electrical or chemical properties, opening up new directions for the development of materials science, and applying it to many fields such as photoelectric display and sensors.
    In summary, 7-chloro-3-methyl-8-quinoline carboxylic acid has shown important value in the fields of medicine, pesticides and materials science, and is of great significance to promote the development of related industries.
    What is the synthesis method of 7-Chloro-3-methyl-8-quinolinecarboxylic acid?
    The synthesis of 7-chloro-3-methyl-8-quinoline carboxylic acid is related to the technique of chemical preparation. This synthesis method is obtained by chemical experts after repeated research and many attempts.
    In the past, if Fang family wanted to obtain this compound, they first chose suitable starting materials. It often starts with quinoline derivatives with a specific structure, whose structure is like the cornerstone of building a mansion, laying the foundation for synthesis. Then, a halogenation method is applied. Under appropriate reaction conditions, chlorine atoms are introduced. Among them, the choice of reaction temperature, pressure, and solvent is the key. If the temperature is too high or side reactions are clustered, if it is too low, the reaction will be slow or even stagnant. The nature of the solvent is related to the solubility of the reactants and the rate and direction of the reaction.
    After the chlorine atom is introduced, the methylation step is carried out. This step requires the use of special methylating reagents and strict control of all elements of the reaction. The amount of reagents and the reaction time must be precisely controlled. If the methylating reagent is excessive or causes excessive methylation, the product is impure; if the amount is small, the methylation is incomplete and it is difficult to obtain the target product.
    Furthermore, in the synthesis process, separation and purification techniques are also indispensable. Due to the complex reaction system, the product is often mixed with impurities. It is necessary to separate the target product from impurities by recrystallization, column chromatography, etc., to obtain pure 7-chloro-3-methyl-8-quinoline carboxylic acid. These many steps are interlinked and indispensable. All of them rely on Fang's profound chemical foundation and rich experimental experience to achieve this synthesis method.
    What is the price range of 7-Chloro-3-methyl-8-quinolinecarboxylic acid in the market?
    The price of 7-chloro-3-methyl-8-quinoline carboxylic acid in the market is difficult to be fixed. The range of its price often changes due to multiple reasons.
    This compound is widely used in the chemical industry, medicine and other fields. If you look at the chemical raw material market, its quality and quantity are abundant, and the price may be slightly lower; if you look at the fine pharmaceutical and chemical supply, due to strict requirements on purity, the price will increase.
    In the past few years, the market situation has changed. The production of raw materials, the increase or decrease in demand, and the regulation of politics are all the reasons for the price movement. Early in life, raw materials are easy to obtain, and there are many producers. The supply exceeds the demand, so the price is low, per kilogram or only a few tens of gold. Later, due to the stricter environmental protection, several factories closed down, and the demand for production has not been reduced. The price has risen, and the price can reach hundreds of gold per kilogram.
    Recently, although production has gradually resumed, the international situation, transportation costs, etc. also disturb its price. Generally speaking, in today's city, if the purity is ordinary, the price per kilogram may be between 100 gold and hundreds of gold; if the high-purity high-quality products, the price per kilogram may exceed 500 gold, or even higher. It is difficult to determine, and it must be judged according to real-time market conditions.
    What are the storage conditions for 7-Chloro-3-methyl-8-quinolinecarboxylic acid?
    7-Chloro-3-methyl-8-quinoline carboxylic acid, this is an organic compound. Its storage conditions are quite important, which is related to the quality and stability of this compound.
    To properly store this compound, the first priority is the drying of the environment. Because it is easy to interact with water vapor or cause deterioration in humid environments, it should be placed in a dry place, and the dryness of the environment can be maintained by desiccant.
    Temperature is also a key factor. It should be stored in a cool place to avoid high temperature. High temperature can easily promote chemical reactions, cause structural changes, and affect its chemical properties. Generally speaking, refrigeration conditions at 2-8 ° C are preferred, which can effectively slow down its chemical change rate.
    Furthermore, it is necessary to pay attention to the ventilation condition of the storage place. Good ventilation can avoid the accumulation of harmful gases, and prevent the quality of compounds from being affected by abnormal local temperature and humidity.
    Packaging should also not be taken lightly. Sealed packaging should be used to prevent the intrusion of air, water vapor and other impurities. If it is packed in glass or plastic bottles, make sure that the bottle cap is tightly sealed. If it is packed in plastic bags, it should also have good sealing.
    During storage, it should be stored separately from oxidants, acids, alkalis and other substances. Due to its active chemical properties, contact with the above substances may cause violent chemical reactions, resulting in danger. In short, the storage of 7-chloro-3-methyl-8-quinolinecarboxylic acid requires a dry, cool, and ventilated environment, suitable packaging, and reasonable partitioning to ensure its quality and safety.