6 Hydroxy 4 Quinolinecarboxylic Acid
quinoline thiophene imidazole thiazole

6-Hydroxy-4-quinolinecarboxylic acid

Taiy Chemical

    Specifications

    HS Code

    176130

    Chemical Formula C10H7NO3
    Molecular Weight 189.17 g/mol
    Appearance Solid (usually powder)
    Melting Point Approx. 290 - 295 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Pka Value There are acidic groups with pKa values relevant to the carboxylic acid and phenolic -OH, e.g., carboxylic acid pKa around 3 - 4
    Uv Absorption Absorbs in the UV region characteristic of quinoline derivatives
    Ir Absorption Peaks Characteristic peaks for C=O (carboxylic acid), C=N, and -OH groups
    Stability Stable under normal conditions but may react with strong oxidizing or reducing agents

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    Frequently Asked Questions

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    What is the chemical structure of 6-Hydroxy-4-quinolinecarboxylic acid?
    6-Hydroxy-4-quinoline carboxylic acid, which is a kind of organic compound. Looking at its name, it can be seen that this compound is derived from the parent structure of quinoline. Quinoline, with the structure of azalaphthalene, is a nitrogen-containing aromatic heterocyclic compound.
    In the quinoline structure, a hydroxyl group is added at position 6 and a carboxyl group at position 4 to form 6-hydroxy-4-quinoline carboxylic acid. The introduction of this hydroxyl group (-OH) and carboxyl group (-COOH) greatly affects the physical and chemical properties of the compound. Hydroxyl groups are hydrophilic and can participate in the formation of hydrogen bonds, which affects the solubility and intermolecular forces of compounds. The carboxyl group is acidic, capable of dissociating hydrogen ions under suitable conditions, exhibiting acidic characteristics, and can participate in many chemical reactions, such as esterification reactions.
    From the perspective of the spatial structure, the rigid planar structure of quinoline gives the compound a specific shape and spatial orientation, and the spatial position of hydroxyl and carboxyl groups also has an important impact on its reactivity and molecular interactions. In the field of chemical synthesis, this compound is often prepared by a specific organic synthesis method, and its unique chemical structure is precisely constructed by selecting suitable starting materials and reaction conditions. This structure may have potential applications in the fields of medicine, materials, etc., because the specific chemical structure is often associated with specific biological activities or material properties.
    What are the physical properties of 6-Hydroxy-4-quinolinecarboxylic acid?
    6-Hydroxy-4-quinoline carboxylic acid, this is an organic compound. Its physical properties are unique, let me tell you in detail.
    Looking at its appearance, under room temperature and pressure, it often shows a white to light yellow crystalline powder state. This shape is delicate and smooth to the touch. Its color is pure, without variegated mottles, highlighting the regular and orderly structure of its internal structure.
    When it comes to solubility, the solubility of this compound in water is quite limited. Water is the source of all things, but 6-hydroxy-4-quinoline carboxylic acid has poor affinity with it. At room temperature, it can only be slightly soluble in water, which seems to be alienated. However, in organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), its solubility is greatly improved. In DMSO, it can dissolve more smoothly, just like a fish entering water, free. This characteristic is due to the fact that its molecular structure contains both hydrophilic hydroxyl groups and hydrophobic quinoline rings, so it behaves differently in different solvents.
    Besides, its melting point has been finely determined to be between 280 ° C and 290 ° C. When the temperature gradually rises, the thermal motion of the compound molecules intensifies, the lattice structure gradually disintegrates, and finally melts from a solid state to a liquid state. This melting point range is stable and clear, which is an important indicator for identifying its purity. If it contains more impurities, the melting point will shift, or decrease, or the melting range will become wider, just like flawed jade, losing its purity.
    Although its density is not exact, it is inferred from similar compounds that it is roughly in the range of 1.4-1.6 g/cm ³. The density is also the degree of compactness of the substance. This range indicates that its molecules are relatively closely arranged and have a stable structure. It is like a ready-to-fight army and is orderly.
    In addition, 6-hydroxy-4-quinoline carboxylic acid is relatively stable chemically at room temperature. When encountering strong acids and alkalis, its structure may change. Strong acids can be protonated with hydroxyl groups, while strong bases can be neutralized with carboxyl groups, as if they encountered an external force impact, their internal balance was broken, and corresponding chemical changes occurred.
    In summary, the unique physical properties of 6-hydroxy-4-quinoline carboxylic acids lay the foundation for their application in many fields such as chemistry and medicine, just as the cornerstone is crucial for high-rise buildings.
    What are the applications of 6-Hydroxy-4-quinolinecarboxylic acid?
    6-Hydroxy-4-quinoline carboxylic acid is used in many fields such as medicine and chemical industry.
    In the field of medicine, it may have significant biological activity. The structure of 6-hydroxy-4-quinoline carboxylic acid is quite common in many drug molecules. With its unique chemical structure, this 6-hydroxy-4-quinoline carboxylic acid may exhibit antibacterial, anti-inflammatory and even anti-tumor effects. Or it can be modified and modified to fit specific targets and develop new drugs. For example, by means of chemical synthesis, different functional groups are added to explore their interaction with biological macromolecules, and then innovative drugs with better efficacy and fewer side effects are developed. < Br >
    In the chemical industry, it has a wide range of uses. It can be used as a key intermediate in organic synthesis. Using it as a starting material, through a series of chemical reactions, a variety of functional materials and fine chemicals can be prepared. For example, it can be used to synthesize fluorescent dyes with specific structures. Because of its special structure or unique optical properties, it plays an important role in fluorescent labeling and biological imaging. Furthermore, in the synthesis of polymer materials, polymer chains can be introduced as structural units to endow materials with special properties, such as improving material thermal stability and mechanical properties.
    In addition, in the agricultural field, there may be potential applications. After rational design and research and development, it may be possible to develop compounds with plant growth regulation effects, help increase crop production and income, or develop new pesticides, enhance the ability to prevent and control pests and diseases, and have a small impact on the environment, which is in line with the current needs of green agriculture development.
    In short, 6-hydroxy-4-quinoline carboxylic acid has broad application prospects in many fields. With the deepening of scientific research and technological progress, its application value may be further demonstrated.
    What is the preparation method of 6-Hydroxy-4-quinolinecarboxylic acid?
    For 6-hydroxy-4-quinoline carboxylic acids, the method of preparation is quite important. There are various paths, and I will describe them in detail.
    First, it can be synthesized through chemical synthesis. With specific starting materials, according to the principle of organic synthesis, it is prepared through several steps. For example, starting with a compound containing quinoline parent nuclei, it is first modified at a specific position to introduce hydroxyl and carboxyl groups. Under precisely controlled reaction conditions, it is often replaced or oxidized with suitable reagents. For example, halogenation can be used to introduce halogen atoms at specific positions in the quinoline ring, and then through nucleophilic substitution reactions, halogen atoms can be replaced by hydroxyl-containing reagents to introduce hydroxyl groups. Then, through a suitable oxidation process, the carboxyl group is constructed at the appropriate position. However, the temperature, pH and reaction time must be carefully controlled to achieve the ideal yield and purity.
    Second, there is also a method of biosynthesis. With the help of microorganisms or enzymes, natural substrates are used as raw materials and synthesized through complex metabolic pathways in the body. Microorganisms with specific metabolic capacity are selected, and under suitable culture conditions, the substrate is converted into 6-hydroxy-4-quinoline carboxylic acid. This process requires fine regulation of factors such as medium composition, temperature, and ventilation, so that the metabolic activities of microorganisms are carried out in the direction of synthesis of the desired products. Biosynthesis often has the advantages of green and environmental protection, but it also faces challenges such as difficult microbial culture and product separation and purification.
    Preparation of 6-hydroxy-4-quinoline carboxylic acid has advantages and disadvantages in chemical synthesis and biosynthesis. It is necessary to weigh the availability of raw materials, cost, environmental impact and other factors according to actual needs, choose the appropriate method, and operate carefully to obtain the ideal product.
    What is the market outlook for 6-Hydroxy-4-quinolinecarboxylic acid?
    6-Hydroxy-4-quinoline carboxylic acid, this substance has considerable market prospects in the current market. In the current trend of pharmaceutical research and development, there is a growing demand for compounds with unique biological activities. 6-Hydroxy-4-quinoline carboxylic acid shows potential application value in the field of medicine due to its special chemical structure.
    In the field of drug synthesis, it can be used as a key intermediate to help create new antibacterial, anti-inflammatory and anti-tumor drugs. Many scientific research teams are working hard on the drug development path based on it. Over time, it may lead to innovative drugs and benefit patients, which will undoubtedly expand its market space.
    Furthermore, with the vigorous development of materials science, the compound has also emerged in the field of optoelectronic materials. Due to its specific optical and electrical properties, it may be applied to the preparation of organic Light Emitting Diodes, sensors and other materials, injecting new impetus into the innovation of materials science, thus opening up new market areas.
    However, its market development is not smooth sailing. The complexity and cost of the synthesis process may hinder its large-scale application. To achieve its wide application, it is necessary to optimize the synthesis route and reduce production costs. Only by overcoming these problems can 6-hydroxy-4-quinoline carboxylic acid bloom in the market, fully release its commercial potential, and achieve brilliant results in the fields of medicine and materials.