6 Bromobenzo H Quinoline
quinoline thiophene imidazole thiazole

6-bromobenzo[h]quinoline

Taiy Chemical

    Specifications

    HS Code

    182565

    Chemical Formula C15H8BrN
    Molar Mass 282.134 g/mol
    Appearance Solid (usually)
    Solubility In Water Low (organic compound, relatively non - polar)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Color Color may vary but often pale - colored solid
    Odor Typically has an organic, slightly pungent odor
    Reactivity Can react with nucleophiles at the bromine position

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    General Information
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    Frequently Asked Questions

    As a leading 6-bromobenzo[h]quinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 6-bromobenzo [h] quinoline?
    6-Bromobenzo [h] quinoline is also an organic compound. It has many chemical properties and is now known as Jun Chen.
    First of all, it has the properties of halogenated aromatics. Due to the bromine atom, this bromine atom has high activity and can participate in nucleophilic substitution reactions. Under suitable conditions, bromine atoms can be replaced by nucleophilic reagents such as hydroxyl (-OH) and amino (-NH2O). For example, when heated with an aqueous solution of sodium hydroxide, under appropriate conditions, the bromine atom may be replaced by a hydroxyl group to form a benzo [h] quinoline derivative containing hydroxyl groups.
    Furthermore, its quinoline-containing fused ring structure makes it aromatic. This aromatic system makes it stable and can participate in the aromatic electrophilic substitution reaction. The electron cloud density at different positions on the thick ring of benzo [h] quinoline is different, so the activity and check point of the electrophilic substitution reaction are also different. Generally speaking, under appropriate catalyst and reaction conditions, halogenation, nitrification, sulfonation and other electrophilic substitution reactions can occur at specific positions of the benzene ring or the quinoline ring.
    And because its molecule contains nitrogen atoms, nitrogen atoms have lone pairs of electrons, so the compound has a certain alkalinity. Although its basicity is weaker than that of aliphatic amines, it can combine with protons in acidic media to form corresponding salts.
    In addition, 6-bromobenzo [h] quinoline also exhibits in redox reactions. Under the action of specific oxidants, its fused ring structure may be oxidized, resulting in changes in its chemical structure and properties; when encountering suitable reducing agents, a reduction reaction may occur, such as partial or complete reduction of the fused ring system.
    6-bromobenzo [h] quinoline has important applications and research values in organic synthesis, pharmaceutical chemistry and other fields due to its own structural characteristics.
    What are the common synthesis methods of 6-bromobenzo [h] quinoline?
    6 - bromobenzo [h] quinoline is also an organic compound. Its common synthesis method is based on the principle of chemical synthesis, and it is obtained from various raw materials and suitable reaction conditions and steps.
    One method is also to use compounds containing benzene ring and quinoline structure as starting materials. Before the specific position of the benzene ring, bromine atoms are introduced by halogenation. Halogenation method, or use brominating agents, such as liquid bromine, N-bromosuccinimide (NBS), etc. If liquid bromine is used, a catalyst, such as iron powder or iron tribromide, is often required to assist the reaction. Iron and bromine react to form iron tribromide, which is Lewis acid, which can polarize bromine molecules, making it easier to undergo electrophilic substitution reaction with benzene rings, and then introduce bromine atoms at the desired position of benzene rings.
    In addition, the construction of quinoline structure is also the key. Often aniline derivatives and carbonyl compounds, such as aldodes or ketones, are reacted under acid-catalyzed or base-catalyzed conditions to form quinoline rings through a series of reactions such as condensation and cyclization. For example, under acidic conditions, o-aminobenzaldehyde and acetone, the condensation reaction first occurs to form a Schiff base, and then the inner ring of the molecule is closed to obtain the quinoline structure. After that, the part of the benzene ring that has been introduced into the bromine atom is connected to the constructed quinoline structure, or through a coupling reaction, such as the Ullmann reaction, using copper powder or copper salt as a catalyst, at high temperature and in the presence of alkali, the bromobenzo ring is connected to the quinoline structure, and then 6-bromobenzo [h] quinoline is obtained.
    Based on other heterocyclic synthesis methods, the gradual modification, transformation, the introduction of bromine atoms and the construction of benzoquinoline structure. In short, the key to synthesis lies in precisely controlling the reaction conditions, selecting the appropriate raw materials and reaction paths, so as to achieve the purpose of efficient synthesis of 6-bromobenzo [h] quinoline.
    What are the applications of 6-bromobenzo [h] quinoline?
    6-Bromobenzo [h] quinoline is useful in various fields.
    In the field of medicine, this compound may have unique biological activity and can be used as a potential drug precursor. In today's pharmaceutical research and development, small molecules with specific structures are often searched to explore their effects on biological targets. The structure of 6-bromobenzo [h] quinoline may interact with specific proteins, enzymes, etc., and is expected to be developed into antibacterial, antiviral and even anti-cancer drugs. If drugs were developed in the past, they were often based on specific structures and modified to find effective drugs.
    In materials science, it can also be used. Because of its structural properties, it may be used to prepare materials with special photoelectric properties. For example, if it is used in the research and development of organic Light Emitting Diode (OLED) materials, it will give the material unique luminous properties and improve the display effect. Or it can be used to prepare sensor materials, and its interaction with specific substances can be used to achieve sensitive detection of specific substances.
    Furthermore, in the field of organic synthetic chemistry, 6-bromobenzo [h] quinoline is often used as a key intermediate. The delicacy of organic synthesis lies in using various intermediates as masonry to construct complex organic molecules. Using this as a starting material, through many reactions such as halogenation and coupling, organic compounds with more complex structures and more specific functions can be synthesized, expanding the types and functions of organic compounds.
    In summary, 6-bromobenzo [h] quinoline has shown important application potential in the fields of medicine, materials science, and organic synthetic chemistry, and has attracted the attention of many scientific researches and industrial practices.
    What are the physical properties of 6-bromobenzo [h] quinoline?
    6 - bromobenzo [h] quinoline is one of the organic compounds. Its physical properties are quite specific, and are described below.
    Looking at its shape, under room temperature and pressure, it is mostly in the shape of a solid state, or in the shape of a crystal, and the quality is relatively stable.
    When it comes to color, it is common to look white to light yellow. The color is pure and soft, like the stamen of a spring day, elegant and pleasing to the eye.
    Smell its smell, usually with a faint aromatic charm. Although it is not rich and pungent, it is also clearly recognizable. It is similar to the ink fragrance that drifts leisurely in ancient books, and has a unique flavor.
    Its melting point also has a specific value, around [X] ° C. This temperature is like a precise scale, defining the transition node between the solid and liquid states of the substance. When the temperature approaches this value, 6-bromobenzo [h] quinoline is awakened like a sleeping spirit, and gradually melts from a solid state to a flowing liquid state, just like melting ice and snow, showing the wonders of material form changes.
    As for the boiling point, it is roughly [X] ° C. At this temperature, the compound will undergo sublimation from a liquid state to a gas state, just like a phoenix nirvana, giving off a new form.
    In terms of solubility, 6-bromobenzo [h] quinoline exhibits good solubility in organic solvents, such as ethanol, chloroform, etc., just like fish entering water and melting freely; however, in water, its solubility is quite limited, just like the barrier between oil and water, and it is difficult to miscible. This difference in solubility also lays a unique foundation for its use in different chemical operations and applications.
    Above the density, it is about [X] g/cm ³. This value gives the material a unique mass and volume relationship, making it occupy a specific spatial position in the material world, just like the stars have their own orbits in the vast universe, showing the close connection between the microscopic and macroscopic properties of matter.
    To sum up, the physical properties of 6-bromobenzo [h] quinoline are unique and orderly, like a delicate ancient painting, with details of each part contrasting each other to form a complete picture of its material properties.
    What is the market outlook for 6-bromobenzo [h] quinoline?
    6 - Bromobenzo [h] quinoline is one of the organic compounds. Today's market prospects are quite promising.
    From the perspective of the field of medicine, it has great potential at the end of drug research and development. Today's medicine is constantly exploring new drugs to treat various diseases. 6 - Bromobenzo [h] quinoline's unique chemical structure makes it a key intermediate for the development of anti-cancer, antibacterial and other drugs. In recent years, the incidence of cancer remains high, and the problem of antimicrobial resistance is becoming more and more serious, so the development of new effective drugs is urgent. Due to the structural characteristics of this compound, it may be combined with specific targets of cancer cells to hinder the proliferation of cancer cells; or it may interfere with the metabolic process of bacteria to achieve antibacterial effect. In the pharmaceutical R & D market, its demand may grow with the advancement of new drug research and development.
    In the field of materials science, 6-bromobenzo [h] quinoline is also promising. With the development of science and technology, the demand for materials with special properties is increasing. This compound may be introduced into polymer materials through specific reactions to give the material special properties such as fluorescence and conductivity. For example, in the research and development of organic Light Emitting Diode (OLED) materials, compounds with fluorescence properties have attracted much attention. 6-bromobenzo [h] quinoline, if properly modified, may become an excellent component of OLED materials, improve its luminous efficiency and stability, and then promote the development of display technology. It can be seen that in the materials science market, it is also expected to occupy a place.
    However, its market development has not been smooth sailing. The process of synthesizing this compound may be difficult and costly. For large-scale application, the synthesis process must be optimized to reduce costs. And its safety and environmental impact also need to be considered in detail. Only by properly solving various problems can 6-bromobenzo [h] quinoline be widely recognized in the market and have a broader prospect.