6 Amino 4 3 Chloro 4 2 Pyridylmethoxy Anilino 7 Ethoxy Quinoline 3 Carbonitrile
quinoline thiophene imidazole thiazole

6-amino-4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-ethoxy-quinoline-3-carbonitrile

    Specifications

    HS Code

    801804

    Chemical Name 6 - amino - 4 - [3 - chloro - 4 - (2 - pyridylmethoxy)anilino]-7 - ethoxy - quinoline - 3 - carbonitrile
    Molecular Formula C26H21ClN4O2
    Molar Mass 460.929 g/mol
    Appearance Solid (predicted)
    Solubility Limited solubility in water, soluble in some organic solvents like DMSO
    Pka Values for acidic and basic groups would depend on their nature in the molecule
    Logp A positive value indicating lipophilic nature (predicted)
    Stability Stable under normal conditions if protected from light, heat and moisture

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    General Information
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    Frequently Asked Questions

    As a leading 6-amino-4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-ethoxy-quinoline-3-carbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 6-amino-4- [3-chloro-4- (2-pyridylmethoxy) anilino] -7-ethoxy-quinoline-3-carbonitrile
    6 - amino - 4 - [3 - chloro - 4 - (2 - pyridylmethoxy) anilino] - 7 - ethoxy - quinoline - 3 - carbonitrile is an organic compound whose main uses are mostly in the field of medicinal chemistry.
    The structure of this compound contains nitrogen heterocycles and various substituents. This unique structure gives it specific chemical and biological properties. In the field of drug development, it is often used as a lead compound. Due to the complexity and diversity of its structure, it can interact with specific targets in organisms.
    First, in the study of anticancer drugs, it may interfere with the growth, proliferation and metastasis of cancer cells by binding to key proteins or enzymes in cancer cells. For example, it may inhibit the activity of specific kinases, which are crucial in cancer cell signaling pathways. Once inhibited, the abnormal proliferation of cancer cells may be curbed.
    Second, it also has potential value in the exploration of antibacterial drugs. Its structure may conform to the activity check points of key metabolic enzymes or cell wall synthesis-related proteins in bacteria, hindering the normal metabolism and cell wall synthesis of bacteria, and achieving antibacterial effect.
    Third, in the development of neuroscience drugs, it may cross the blood-brain barrier and interact with neurotransmitter receptors or related signaling proteins, providing new ideas and directions for the treatment of neurological diseases such as Alzheimer's disease and Parkinson's disease.
    Due to its structural properties, this compound has potential uses in various directions in the field of medicine, bringing many possibilities for the creation of new drugs.
    What are the chemical properties of 6-amino-4- [3-chloro-4- (2-pyridylmethoxy) anilino] -7-ethoxy-quinoline-3-carbonitrile
    6-Amino-4- [3-chloro-4- (2-pyridyl methoxy) aniline] -7-ethoxy-quinoline-3-formonitrile, this is an organic compound. Looking at its structure, it is based on the quinoline parent nucleus, connected with amino, cyano, ethoxy, and the benzene ring contains chlorine atoms and pyridyl methoxy aniline groups.
    In terms of its chemical properties, amino groups are basic and can form salts with acids. Under specific conditions, they may participate in nucleophilic substitution, condensation and other reactions. The cyanyl group has good activity, can be hydrolyzed to carboxyl groups, or reduced to amino groups, and can also undergo addition reactions with compounds containing active hydrogen.
    The chlorine atom on the benzene ring can be replaced by nucleophilic reagents under appropriate reagents and conditions. Due to the electron absorption of chlorine atoms, the electron cloud density of the benzene ring changes, which affects the electrophilic substitution activity of the aromatic ring. The pyridine methoxy aniline part, the pyridine ring is basic, and the methoxy group is the power supply group, which has an impact on the electron cloud distribution of the benzene ring. The nitrogen atom of the aniline group also has nucleophilic properties, or can participate in various reactions.
    The oxygen atom in the ethoxy group contains lone pairs of electrons, which can be complexed with metal ions or participate in reactions such as ether bond This compound exhibits rich chemical reactivity due to its diverse substituents, and may have potential uses in organic synthesis, medicinal chemistry, etc. It can be used as an intermediate for the synthesis of complex compounds, or as a lead compound for drug development due to specific activities.
    What is the synthesis method of 6-amino-4- [3-chloro-4- (2-pyridylmethoxy) anilino] -7-ethoxy-quinoline-3-carbonitrile
    6 - amino - 4 - [3 - chloro - 4 - (2 - pyridylmethoxy) anilino] - 7 - ethoxy - quinoline - 3 - carbonitrile is an organic compound. The method of synthesizing this compound often requires multiple steps and delicate reactions.
    At the beginning, an appropriate quinoline derivative can be selected as the raw material. First, the quinoline derivative undergoes a nucleophilic substitution reaction with aniline compounds containing chlorine and pyridylmethoxy under suitable reaction conditions. This reaction requires fine regulation of reaction temperature, time and ratio of reactants to allow the chlorine atom to be successfully replaced by phenylamine to obtain a quinoline intermediate containing a specific substituent. < Br >
    Then, ethoxylation is carried out at a specific position of the resulting intermediate. It is often necessary to choose a strong base and react with the ethoxylation reagent in a suitable organic solvent. In this process, the strong base can assist the intermediate to generate nucleophilic species, so that it can be smoothly combined with the ethoxylation reagent to introduce ethoxy groups.
    Furthermore, cyanylation is carried out for the intermediate. This step may require a cyanide reagent, with the help of a specific catalyst, in a suitable reaction system, to introduce a cyanide group at a specific position on the quinoline ring. The choice of catalyst and the control of the reaction environment are crucial, and the efficiency and selectivity of cyanylation are related.
    Finally, the resulting product is purified. Classic purification methods such as column chromatography and recrystallization are often used to remove impurities and obtain high-purity 6-amino-4- [3-chloro-4- (2-pyridylmethoxy) anilino] -7-ethoxy-quinoline-3-carbonitrile. Every step of the reaction needs to be carefully observed and precisely controlled to obtain the ideal synthetic effect and obtain the target compound.
    What is the price of 6-amino-4- [3-chloro-4- (2-pyridylmethoxy) anilino] -7-ethoxy-quinoline-3-carbonitrile in the market?
    Guan Jun's question is about the market price of "6 - amino - 4 - [3 - chloro - 4 - (2 - pyridylmethoxy) anilino] - 7 - ethoxy - quinoline - 3 - carbonitrile". However, this thing is not a common and familiar thing in my time, and I do not know its exact market price.
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    6-Amino-4- [3-chloro-4- (2-pyridylmethoxy) anilino] -7-ethoxy-quinoline-3-carbonitrile
    6-Amino-4- [3-chloro-4- (2-pyridylmethoxy) anilinyl] -7-ethoxyquinoline-3-formonitrile is an organic compound. Many matters need to be paid attention to when it comes to the safety of this compound.
    First of all, the way of protection should not be ignored. This substance may be irritating, and protective gear is indispensable when exposed. When touching hands, you must wear chemical protective gloves, such as nitrile gloves, to protect the skin of your hands; if there is a risk of eye contact, safety goggles or full masks should be worn at any time to ensure the safety of your eyes; respiratory protection is also key. In places with poor ventilation or where dust may be generated, appropriate respiratory protective equipment, such as filter gas masks, should be worn to prevent harmful particles from entering the body.
    Secondly, the operating environment must be kept in mind. The operation of this compound should be carried out in a well-ventilated place, so that it can quickly disperse harmful gases or dust that may be generated. If conditions permit, it can be operated in a fume hood to strengthen protection. The operating room should also be kept away from fire and heat sources, because it may be flammable, it is extremely important to prevent fire risks.
    Furthermore, storage methods are also exquisite. It should be stored in a cool, dry and ventilated place, away from oxidants and acids, to prevent chemical reactions. Storage containers should be well sealed to avoid leakage, and the name of the compound and relevant warning information should be clearly marked on the container.
    Finally, waste disposal must be in compliance. Residual or discarded compounds must not be discarded at will. They should be properly collected and disposed of in accordance with local regulations and laboratory regulations, or handed over to a professional waste treatment facility to avoid pollution to the environment.
    In conclusion, when using 6-amino-4- [3-chloro-4- (2-pyridyl methoxy) anilinyl] -7-ethoxyquinoline-3-formonitrile, all aspects of protection, operation, storage and waste disposal need to be treated with caution to ensure personnel safety and environmental harmlessness.