6 Amino 1 2 3 4 Tetrahydroquinoline
quinoline thiophene imidazole thiazole

6'-AMINO-1,2,3,4-TETRAHYDROQUINOLINE

Taiy Chemical

    Specifications

    HS Code

    248856

    Chemical Formula C9H12N2
    Molar Mass 148.205 g/mol
    Appearance Solid (usually)
    Odor May have a characteristic amine - like odor
    Melting Point Varies, typically in a certain range depending on purity
    Boiling Point Varies, influenced by purity and pressure
    Solubility In Water Slightly soluble or sparingly soluble
    Solubility In Organic Solvents Soluble in some common organic solvents like ethanol, dichloromethane
    Pka Value Related to its basicity, specific value depending on environment
    Basicity It is a basic compound due to the amine group
    Flash Point A value indicating flammability risk, specific to the compound

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    General Information
    Where to Buy 6'-AMINO-1,2,3,4-TETRAHYDROQUINOLINE in China?
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    Frequently Asked Questions

    As a leading 6'-AMINO-1,2,3,4-TETRAHYDROQUINOLINE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 6 '-AMINO-1,2,3, 4-TETRAHYDROQUINOLINE
    6-Amino-1,2,3,4-tetrahydroquinoline is used in various fields such as medicine and chemical industry.
    In the field of medicine, this compound is often a key intermediate for the synthesis of many drugs. Because of its unique chemical structure, it can interact with specific targets in organisms, so it plays an important role in the development of drugs for the treatment of nervous system diseases, cardiovascular diseases and anti-tumor drugs. For example, some studies have developed drugs with high affinity for certain neurotransmitter receptors by virtue of their structural properties and modification, which are expected to improve related nervous system dysfunction.
    In the chemical industry, 6-amino-1,2,3,4-tetrahydroquinoline can be used as an important raw material for organic synthesis. It can participate in many organic reactions to prepare various functional materials, dyes and fragrances. Because its structure endows compounds with specific optical and electrical properties, it is also of interest in the development of optoelectronic materials, or can be used to create new luminescent materials, which can be used in display technology and other fields.
    Furthermore, at the level of scientific research and exploration, 6-amino-1,2,3,4-tetrahydroquinoline is an important object in organic chemistry and pharmaceutical chemistry research. By studying their reaction characteristics and structure-activity relationships, researchers gain in-depth insight into the reaction mechanism and biological activity laws of organic molecules, laying a theoretical foundation for the development of more efficient and low-toxicity compounds, and promoting the continuous progress of chemistry and medical science.
    What are the chemical properties of 6 '-AMINO-1,2,3, 4-TETRAHYDROQUINOLINE
    6-Amino-1,2,3,4-tetrahydroquinoline, this is an organic compound. It has unique chemical properties and has important uses in many chemical fields.
    Looking at its structure, it contains the backbone of tetrahydroquinoline and has an amino group attached at the 6 position. The presence of amino groups gives this compound unique reactivity. Amino is a nucleophilic group and can participate in many nucleophilic reactions. For example, it can undergo nucleophilic substitution reactions with halogenated hydrocarbons to form new carbon-nitrogen bonds. This reaction can be used to construct more complex organic molecular structures.
    Furthermore, it also has characteristics in terms of acidity and alkalinity. Amino groups can accept protons and exhibit certain alkalinity. Under appropriate acidic conditions, amino groups can be protonated to form ammonium ions, which affects their solubility and reactivity in solution. Due to the basicity of amino groups, 6-amino-1,2,3,4-tetrahydroquinoline can form salts with acids, and the resulting salts may have unique applications in some organic synthesis reactions or pharmaceutical preparations.
    In addition, the tetrahydroquinoline skeleton is also an important structural unit. This skeleton imparts certain rigidity and spatial structure to the compound, which affects the physical and chemical properties of the molecule. The unsaturated bonds of the tetrahydroquinoline moiety can participate in addition reactions, such as addition with hydrogen, which can further saturate its structure and change the physical properties and reactivity of the compound. 6-Amino-1,2,3,4-tetrahydroquinoline is rich in chemical properties and has important research value and application potential in the fields of organic synthesis and medicinal chemistry. It can be used as a key intermediate for the synthesis of a variety of organic compounds with biological activity or special functions.
    What are the synthesis methods of 6 '-AMINO-1,2,3, 4-TETRAHYDROQUINOLINE
    The methods for synthesizing 6-amino-1, 2, 3, 4-tetrahydroquinoline are many different, and with the changes of the world, the chemical methods are also constantly evolving. Today is the common end of the monarch.
    First, using o-aminobenzaldehyde and acetone as starting materials, through condensation reaction, the enamine intermediate can be obtained. This step requires suitable acid-base conditions to help the reaction go smoothly. Then in the catalytic hydrogenation step, a noble metal catalyst, such as palladium carbon, is used to hydrogenate and reduce unsaturated bonds such as enamines and aldehyde groups at a certain temperature and pressure, and finally 6-amino-1, 2, 3, 4-tetrahydroquinoline is obtained.
    Second, aniline derivatives and acrylates can also be used as raw materials. First, the Michael addition reaction occurs between the two to form the key intermediate. This reaction requires careful control of the reaction temperature and the ratio of the reactants to obtain a high yield intermediate. Subsequently, the intermediate undergoes an intramolecular cyclization reaction under acidic or basic conditions to form a quinoline ring system. After a reduction step, the quinoline ring is partially hydrogenated to obtain the target product.
    Third, there are still those who use halogenated aniline and halogenated acetophenone as starting materials. First, the two undergo a nucleophilic substitution reaction to form a carbon-nitrogen bond. In the reaction, the appropriate base and solvent are quite important, which are related to the reaction rate and selectivity. Subsequent steps such as cyclization and reduction can also synthesize 6-amino-1,2,3,4-tetrahydroquinoline.
    All these methods have their own advantages and disadvantages. The experimenter should carefully choose the synthetic method used according to the actual situation, such as the availability of raw materials, cost, and difficulty of reaction conditions.
    What is the price range of 6 '-AMINO-1,2,3, 4-TETRAHYDROQUINOLINE in the market?
    I look at what you are inquiring about, but it is "what is the price range of 6-amino-1,2,3,4-tetrahydroquinoline in the market". However, the price of this chemical product is not constant and often changes for a variety of reasons.
    First, the quality is the main reason. If the product has high purity and few impurities, it is suitable for high-end scientific research or fine chemicals, and its price is high; if the purity is slightly lower, it is only used for ordinary industrial purposes, and the price is slightly lower.
    Second, the trend of supply and demand also affects its price. If the market has strong demand for this product and the supply is limited, it is like the supply is in short supply, and the price will rise; conversely, if the supply exceeds the demand, the price will fall.
    Third, the manufacturing cost is also the key. The price of raw materials, the simplicity of the preparation process, and the amount of energy consumption all affect the final selling price. The price of raw materials is high, the process is complex, and the cost increases and the price rises.
    Fourth, regional differences also have an impact. In different places, due to differences in transportation costs, tax policies, etc., the price may vary.
    As for the exact price range, it is difficult to determine quickly. In the market, the price may range from a few yuan per gram to tens of yuan, or even higher, depending on the above factors. For accurate prices, you can consult chemical raw material suppliers, chemical reagent sellers, or refer to the quotations of chemical product trading platforms.
    What are the storage conditions for 6 '-AMINO-1,2,3, 4-TETRAHYDROQUINOLINE
    6-Amino-1,2,3,4-tetrahydroquinoline is a kind of organic compound. Its storage conditions are crucial and related to the stability and quality of this substance.
    According to the ancient meaning of "Tiangong Kaiwu", where you store objects, the first environment is appropriate. 6-Amino-1,2,3,4-tetrahydroquinoline should be placed in a cool and dry place. Cover a cool place to avoid the disturbance of high temperature. High temperature often increases the molecular activity of the substance, or causes it to undergo chemical reactions, changing the original properties. If it is too heated, it may cause reactions such as decomposition and polymerization, which will damage its purity and structure.
    Dry environment is also indispensable. Water vapor in the air, if it comes into contact with 6-amino-1,2,3,4-tetrahydroquinoline too much, or causes hydrolysis. Especially if this substance contains groups that can interact with water, it is easy to change in contact with water and lose its original appearance.
    In addition, it is necessary to avoid light and shade. Light is also an inducing factor for chemical reactions. Light in certain bands can provide energy, excite molecular transitions, and initiate photochemical reactions. 6-amino-1,2,3,4-tetrahydroquinoline is exposed to light, or causes structural changes, affecting its use.
    And should be isolated from oxidants and other substances. 6-Amino-1,2,3,4-tetrahydroquinoline has specific chemical properties and is prone to oxidation when exposed to oxidants. This reaction may be violent or slow, but it can change the chemical composition and properties of the substance, so it needs to be kept away.
    On storage utensils, suitable materials should be selected. Glass containers, if their chemical stability is good, can be selected. However, it should be noted that some glass components or weak interactions with compounds, so if necessary, special plastic containers can also be selected, provided that the plastic does not react with 6-amino-1,2,3,4-tetrahydroquinoline. Proper storage can ensure that 6-amino-1,2,3,4-tetrahydroquinoline maintains its inherent properties for a certain period of time, so that it can develop its function when needed.