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What are the main uses of 6,7-dimethoxy-4-chloroquinoline?
6,7-Diethoxy-4-formylcoumarin is an important organic compound whose main uses are as follows:
1. ** Pharmaceutical field **: This compound has potential biological activity and is of great significance for drug development. It may have certain antioxidant, anti-inflammatory and anti-tumor activities. From the perspective of traditional herbal philosophy, many natural active ingredients can be used as medicine to treat diseases. For example, "Compendium of Materia Medica" contains a variety of herbs that can cure and save people due to their specific active ingredients. 6,7-Diethoxy-4-formylcoumarin or because of its structural properties, can act on human cell targets and regulate physiological functions. Modern studies have shown that coumarins can inhibit the proliferation of tumor cells by affecting cell signaling pathways, so this compound may provide a lead structure for the development of new anti-tumor drugs.
2. ** Material Science **: In the field of materials science, it can be used as a raw material for the synthesis of functional materials. Coumarins can be used to prepare photoresponsive materials due to their unique photophysical properties. 6,7-diethoxy-4-formyl coumarins or the introduction of ethoxy and formyl groups makes their photophysical properties better. Or it can be introduced into polymer materials through chemical modification to prepare materials with photochromic, fluorescent and other properties for anti-counterfeiting, sensors and other fields. For example, in ancient times, anti-counterfeiting labels were made with special materials to prevent counterfeiting, and the same is true for making new anti-counterfeiting materials with this compound today.
3. ** Organic synthesis intermediates **: As an organic synthesis intermediate, its status is critical. With its own functional groups such as ethoxy and formyl groups, a variety of organic reactions can occur, such as nucleophilic addition and substitution reactions. With this, compounds with more complex structures and specific functions can be synthesized. For example, "Tiangong Kai" contains many methods of creation, and the required materials can be synthesized from raw materials through different steps. In organic synthesis, with 6,7-diethoxy-4-formylcoumarin as the starting material, through multi-step reaction, natural product analogs or new organic compounds with special functions can be prepared, which enriches the variety of organic compounds and meets the needs of different fields.
What are the physical properties of 6,7-dimethoxy-4-chloroquinoline?
6,7-Diethoxy-4-bromobenzaldehyde is an organic compound with special physical properties and is widely used in chemical, pharmaceutical and other fields. Its physical properties are as follows:
1. ** Appearance **: Usually white to light yellow crystalline powder or solid. This appearance feature is convenient for preliminary identification and judgment in actual operation. When different purity or impurities exist, the appearance may be slightly different, but its main color and morphology are relatively stable.
2. ** Melting point **: The melting point range is about 72-76 ° C. As an important physical constant of organic compounds, the melting point is of great significance for the identification of the purity of this substance. By accurately measuring the melting point and comparing it with the literature value, its purity can be judged. If the melting point deviates from the standard range, or the melting range becomes wider, it often indicates that impurities are mixed in.
3. ** Solubility **: Slightly soluble in water, easily soluble in organic solvents such as ethanol, ether, and chloroform. This property is related to the molecular structure. The molecules contain hydrophobic phenyl rings and ethoxy groups, resulting in low solubility in water; while the organic solvent and the compound molecules can form similar intermolecular forces, thus exhibiting good solubility. This solubility is used in organic synthesis for product separation and purification. If recrystallization is carried out with a suitable organic solvent, the purity of the product can be improved.
4. ** Odor **: has a weak special odor. Although the odor description is highly subjective, this faint and special odor can assist in the identification of the substance, and during operation, the odor can also remind the operator to take protective measures to ensure safety.
Is the chemical properties of 6,7-dimethoxy-4-chloroquinoline stable?
6,7-diethoxy-4-methylcoumarin is an organic compound, and its chemical properties are relatively stable under specific conditions.
This compound contains a core structure of coumarin, which gives it certain stability. Coumarin-like compounds usually have a lactone ring structure, and the same is true for 6,7-diethoxy-4-methylcoumarin. Under normal environmental conditions, such as room temperature, room pressure and no special chemical reagents, its lactone ring can be maintained relatively stable, and it is not easy to spontaneously react such as ring opening.
However, its stability is not absolute. In strong acid or alkali environments, lactone rings are affected. In case of strong acids, protonation may occur, which may lead to ring opening of the lactone ring and generate corresponding acid derivatives; in case of strong bases, the ring opening of the lactone ring may be promoted by reactions such as nucleophilic substitution. In addition, high temperature conditions may also reduce the stability of the compound, triggering decomposition or rearrangement reactions. However, in general laboratory storage conditions, such as cool, dry and no special chemical interference, it can maintain relatively stable chemical properties for a certain period of time, and can be used for subsequent chemical research, synthetic reactions or as a raw material in specific fields.
What are the synthesis methods of 6,7-dimethoxy-4-chloroquinoline?
The synthesis method of 6,7-dimethoxy-4-bromo-distyrene is often carried out by organic synthetic chemistry. There are several methods:
One is the synthesis of aryl halide with alkenyl boric acid or borate ester by Suzuki coupling reaction. This reaction requires a palladium catalyst, such as tetra (triphenylphosphine) palladium (0), in the presence of a base, such as potassium carbonate, sodium carbonate, etc., in a suitable solvent, such as a mixed solvent of dioxane, toluene and water. The halogen atom of the aryl halide is coupled with the boron atom of the alkenyl boric acid to form a carbon-carbon bond, and then the skeleton of the target molecule is constructed. The advantage is that the reaction conditions are milder and the tolerance of functional groups is good; however, the disadvantage is that the catalyst cost is higher and the preparation of some borate esters is more cumbersome.
Second, through the Wittig reaction. React with an aldehyde or ketone and a Wittig reagent (phosphorus ylide) to form a carbon-carbon double bond to obtain the target olefin structure. The Wittig reagent can be prepared by reacting halogenated hydrocarbons with triphenylphosphine and then treated with a base. This reaction condition is relatively easy to control and can effectively introduce double bonds; however, the separation of its by-product triphenylphosphine oxide is more troublesome, and the preparation of the Wittig reagent is sometimes more complicated.
Third, use the Heck reaction. Using aryl halide and olefin as raw materials, under the action of palladium catalyst and base, it is reacted in an appropriate solvent. This reaction can effectively form carbon-carbon double bonds, and there are certain rules for the selectivity of substrates; however, the reaction conditions are sometimes harsh, and the catalyst dosage and reaction temperature need to be precisely controlled.
The above synthesis methods have their own advantages and disadvantages. In the actual synthesis, it is necessary to carefully choose the appropriate method according to the availability of raw materials, cost considerations, and difficulty in controlling the reaction conditions, so as to achieve the purpose of efficient and economical synthesis of 6,7-dimethoxy-4-bromo distyrene.
What is the market price of 6,7-dimethoxy-4-chloroquinoline?
Wen Jun inquired about the price of 6% 2C7-diethoxy-4-cyanobenzaldehyde in the market. This is a fine chemical product, and its price often changes for various reasons.
First, it is about quality. Those with high quality and high purity will cost a lot; if the quality is inferior and miscellaneous, the price will be low. Second, the quantity is also heavy. Those who buy a lot, merchants may give discounts to promote sales, and if the quantity is small, the unit price may be high. Third, the supply and demand of the city determines its price. Demand exceeds supply, and the price will rise; supply exceeds demand, and the price will be suppressed. Fourth, the source and the journey fee are involved. If you come from a distance and add freight, the price will increase; if you produce it locally, there will be no long-distance fee, or the price will be low.
I have heard that the price per kilogram of this product is in the state of high quality and moderate quantity, or between hundreds of gold and thousands of gold. However, the market is volatile, and the price is indeterminate, rising and falling from time to time, changing rapidly. To know the exact price, do not consult chemical material suppliers, trading houses, or explore the platform for chemical product trading, in order to obtain the current actual price for operation and research.