6 7 Dihydro 5h Quinoline 8 One
quinoline thiophene imidazole thiazole

6,7-Dihydro-5H-Quinoline-8-One

Taiy Chemical

    Specifications

    HS Code

    823181

    Chemical Formula C9H9NO
    Molecular Weight 147.174 g/mol
    Appearance Solid (predicted)
    Boiling Point 340.6±42.0 °C at 760 mmHg (predicted)
    Melting Point 182 - 186 °C
    Density 1.196±0.06 g/cm3 (predicted)
    Flash Point 159.8±27.9 °C (predicted)
    Solubility Soluble in DMSO, Methanol
    Logp 1.43 (predicted)
    Pka 15.19±0.46 (Predicted)

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    General Information
    Where to Buy 6,7-Dihydro-5H-Quinoline-8-One in China?
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    Frequently Asked Questions

    As a leading 6,7-Dihydro-5H-Quinoline-8-One supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 6,7-dihydro-5H-quinoline-8-one?
    6,7-Dihydro-5H-pyrrolido [2,3-d] pyrimidine-8-ol. This substance is rarely recorded in Danish classics and herbal compendiums, but has been studied in detail in recent times. Its uses are widely involved in the fields of medicine and chemical industry.
    In the field of medicine, it is a key raw material for the creation of new anti-cancer drugs. Cancer diseases and diseases are suffering all over the world. This compound can inhibit the proliferation of cancer cells and inhibit their migration by a specific molecular mechanism, just like setting an obstacle in the way of cancer cells raging. Taking a certain type of solid tumor as an example, after complex laboratory tests, the drug containing this ingredient can accurately target the key signaling pathways of cancer cells, causing the cancer cell cycle to stagnate and apoptosis to occur.
    In the field of chemical industry, it is used as a starting point for the synthesis of special functional materials. Today's technology is changing, and the material requirements are diverse. Polymer materials with this structure exhibit specific electrical and optical properties. If applied to organic optoelectronic components, it can optimize the charge transfer efficiency, improve the luminous efficiency of the components, and make the performance of display screens, lighting fixtures and other optoelectronic devices jump, just like a source of vitality.
    In addition, the path of scientific research and exploration is an important probe for biological activity research. Scholars use its structural characteristics to explore various biochemical reaction mechanisms in organisms, gain insight into the subtle mysteries of life processes, such as exploring the interaction between specific proteins and small molecules, and open up new ideas for new drug research and development, disease diagnosis and treatment. It is like a key to opening the door to unknown territory.
    What are the physical properties of 6,7-dihydro-5H-quinoline-8-one?
    6,7-Dihydro-5H-pyrrolido [3,4-d] pyrimidine-8-ol, which has a variety of physical properties. Its appearance is often white to off-white crystalline powder, which is easy to observe and handle. In many chemical experiments and industrial production processes, this appearance property helps to initially identify and control quality.
    In terms of solubility, it shows a certain solubility in some organic solvents, such as common organic solvents methanol and ethanol, which can interact with it and partially dissolve it, while its solubility in water is relatively weak. This property is of great significance in the separation, purification and construction of reaction systems of substances, which can be effectively separated and refined by virtue of differences in solubility in different solvents.
    Melting point is also a key physical property, and its melting point is in a specific temperature range, which is extremely important for material purity testing. If the purity of the substance is high, the melting point is usually stable and close to the theoretical value; when the purity is poor, the melting point will fluctuate or the melting point range will be widened.
    Furthermore, 6,7-dihydro-5H-pyrrolido [3,4-d] pyrimidine-8-ol has certain stability, but under certain conditions, such as high temperature, strong acid, strong base environment, its structure will change. High temperature may cause the internal chemical bond vibration of the molecule to intensify, triggering decomposition or rearrangement reactions; strong acids and strong bases will chemically react with some functional groups in the molecule, changing its chemical structure and properties. Therefore, when storing and using the substance, these factors need to be fully considered, and appropriate environmental conditions should be selected to ensure the stability of its chemical structure and properties.
    Is the chemical properties of 6,7-dihydro-5H-quinoline-8-one stable?
    The properties of 6,7-dihydro-5H-pyrrolido [2,3-d] pyrimidine-8-ol are relatively stable. From the perspective of its structure, the pyrimidine ring has a certain aromaticity, which endows the compound with a certain stability basis. The conjugate structure of the ring system allows electrons to delocalize within a certain range, reducing the energy of the system, thereby enhancing the overall stability.
    The alcohol hydroxyl group of 6,7-dihydro-5H-pyrrolido [2,3-d] pyrimidine-8-ol has a certain activity, but due to its chemical environment, it forms a certain interaction with the ring system, so that the activity of the hydroxyl group is not too high and affects the stability of the whole compound. And the rigid structure formed by the fused pyrrole ring and the pyrimidine ring restricts the free rotation of the molecule and reduces the possible instability factors caused by conformational changes.
    However, under specific conditions, such as strong acidic or strong basic environment, high temperature and the presence of specific chemical reaction reagents, the stability of the compound may be affected. For example, under strong acidic conditions, the hydroxyl group of alcohol may undergo protonation, which may initiate a series of reactions and affect its stability. However, in general conventional conditions, such as normal temperature, neutral environment and ordinary organic solvents, 6,7-dihydro-5H-pyrrolido [2,3-d] pyrimidine-8-ol can maintain relatively stable chemical properties.
    What are the synthesis methods of 6,7-dihydro-5H-quinoline-8-one?
    To prepare 6,7-dihydro-5H-pyran-8-one, there are many methods. Ancient Fangjia, or starting from the basic raw materials, follows the usual path of organic synthesis, and achieves the purpose through a series of reactions.
    First, a compound containing a suitable functional group can be selected as the starting material. If the enol structure is used, the nucleophilic addition reaction is used to make the activity check point of the enol interact with a specific reagent, adding the necessary atoms or groups, and then constructing the basic skeleton of the pyranone. In the reaction, the choice of suitable solvents and catalysts is the key. If an inert organic solvent is used as a medium, supplemented by a specific metal salt catalyst, the reaction can be carried out efficiently and the yield of the product can be increased.
    Second, the cyclization reaction can also be started. Select a substance containing an appropriate chain structure and reactive end groups to induce intra-molecular cyclization under specific conditions. For example, using a chain compound containing carboxyl groups and alkenyl groups as raw materials, under conditions such as acid catalysis or heating, the carboxyl groups and alkenyl groups are cyclized within the molecule to form a pyranone ring system. This process requires precise regulation of the reaction temperature, time and ratio of reactants to obtain the target product.
    Third, or by means of rearrangement reaction. Compounds with similar structures but need to be rearranged are first prepared, and then the molecules are rearranged by heat, light or catalyst to achieve atomic migration and bond rearrangement to construct the structure of 6,7-dihydro-5H-pyran-8-one. Here, the rearrangement mechanism is studied in detail, and the appropriate reaction conditions can be selected to ensure that the reaction occurs according to the expected path.
    All these methods have advantages and disadvantages. Experimenters need to make careful choices according to their own conditions, the availability of raw materials, the difficulty of the reaction, and many other factors, in order to achieve the purpose of synthesis.
    What is the price range of 6,7-dihydro-5H-quinoline-8-one in the market?
    The price range of 6,7-dihydro-5H-pyrrolio-8-ketone is difficult to determine when it is on the market. The fluctuation of its price is related to many reasons.
    First, the purity of this product has a huge impact on the price. If the purity is extremely high, it is almost flawless, and it is suitable for precision pharmaceutical research and development, high-end chemical experiments and other fields, the price must be high, or it can reach the high price range; if the purity is slightly lower, it can only be used for general industrial purposes, and the price will be correspondingly lower.
    Second, the supply and demand situation of the city also affects its price. If there are many seekers, but the supply is scarce, the so-called scarcity is the most expensive, and the price will rise; on the contrary, if the market supply is abundant and the demand is few, the price may drop in order to sell out.
    Third, the cost of raw materials is also the key. If raw materials are difficult to obtain, or due to limited origin and difficult collection, the cost will rise, and the price of this product will also rise; if raw materials are easily available and the cost is controllable, the price will be relatively stable.
    Fourth, the production process is also related to the price. Complex and delicate processes require high-end equipment and professional talents, and the cost will increase greatly, and the price will be higher; while simple processes will reduce the cost and make the price more affordable.
    Overall, 6,7-dihydro-5H-pyrrolido-8-ketone is in the market price range, as low as tens of currency units per unit quality, and as high as hundreds or even higher, depending on the above factors.