5 Sulfo 8 Hydroxyquinoline
quinoline thiophene imidazole thiazole

5-Sulfo-8-hydroxyquinoline

Taiy Chemical

    Specifications

    HS Code

    827322

    Chemical Formula C9H7NO5S
    Molar Mass 241.22 g/mol
    Appearance Typically appears as a solid
    Solubility In Water Somewhat soluble in water
    Solubility In Organic Solvents Soluble in certain organic solvents
    Pka Value Related to its acidic functional groups, values exist for different dissociation steps
    Color May have a characteristic color, often light - colored solid
    Odor May have a faint characteristic odor

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    General Information
    Where to Buy 5-Sulfo-8-hydroxyquinoline in China?
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    Frequently Asked Questions

    As a leading 5-Sulfo-8-hydroxyquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-Sulfo-8-hydroxyquinoline?
    5 - Sulfo - 8 - hydroxyquinoline is an important organic compound. Its main use is quite extensive.
    First, in the field of analytical chemistry, it is often used as a chelating agent for metal ions. Because it can form stable chelates with many metal ions, and the chelates formed have their own characteristics, it can be used by spectrophotometry and other means to achieve qualitative and quantitative analysis of metal ions. For example, after binding with some transition metal ions, the color and absorption spectrum have specific performance, so that the content of metal ions can be accurately determined, which is significant in ore analysis, water quality monitoring and so on.
    Second, in the field of materials science, due to its unique structure and properties, it can be used to prepare functional materials. If it is introduced into polymer materials, it can endow the material with specific optical, electrical or chemical properties, improve the comprehensive properties of the material, and then expand the application range of the material, playing an important auxiliary role in the development process of new materials.
    Third, in the field of medicine, it also has potential application value. Because of its certain biological activity, some studies have shown that it has specific effects on certain microorganisms or cells. Although it has not been widely used in clinical practice, it provides new ideas and directions for drug development. Researchers are exploring its medicinal potential in order to develop new drugs.
    In conclusion, 5-Sulfo-8-hydroxyquinoline has shown important uses in analytical chemistry, materials science, medicine and other fields due to its diverse properties. With the deepening of research, its application prospects are expected to be broader.
    What are the physical properties of 5-Sulfo-8-hydroxyquinoline?
    5 - Sulfo - 8 - hydroxyquinoline is one of the organic compounds. Its physical properties are considerable and it has a wide range of uses in various fields.
    Under normal conditions, this compound may be in a solid state, with a color ranging from light yellow to brown, and its shape may be crystalline with a fine texture. Its melting point can reach a certain exact value under certain conditions, which is the key to defining its physical state transition. When heated to this melting point, it gradually melts from a solid state to a liquid state, and this process shows its thermal stability.
    As for solubility, 5-Sulfo-8-hydroxyquinoline has limited solubility in water, but it can exhibit better solubility in specific organic solvents, such as alcohols and ketones. This property makes it possible to select suitable solvents according to actual needs in various chemical operations to achieve the purpose of dissolution, reaction or separation.
    Furthermore, its density is also an important physical property. The density of this substance gives it unique distribution characteristics in different media, which is of great significance in the separation of mixtures and the construction of specific systems.
    In addition, 5-Sulfo-8-hydroxyquinoline also has optical performance. It may have a specific absorption spectrum, and under specific wavelengths of light, it can absorb light energy, presenting a unique optical signal. This optical property lays the foundation for its application in the field of analytical chemistry, and it can be accurately determined qualitatively and quantitatively by means of spectral analysis.
    In conclusion, the physical properties of 5-Sulfo-8-hydroxyquinoline are rich and diverse, and these properties are interrelated, which together determine its unique use and value in many fields such as chemistry and materials science.
    What is the chemistry of 5-Sulfo-8-hydroxyquinoline?
    5-Sulfonyl-8-hydroxyquinoline is one of the unique characteristics of organic compounds. Its chemical properties are special, and it has both acidic and coordination properties.
    Looking at its acidity, because there are hydroxyl groups in its molecules, protons can be released under suitable conditions, showing the sign of acidity. This property enables it to combine with alkali substances to form corresponding salts. And its sulfonyl group is also acidic, which can further enhance the overall acidic characteristics.
    In terms of coordination, the nitrogen and oxygen atoms of the 8-hydroxyquinoline part have lone pairs of electrons and can act as coordination atoms. It can combine with many metal ions to form stable coordination compounds. This coordination reaction is widely used in the field of analytical chemistry and is often used for qualitative and quantitative analysis of metal ions.
    In addition, 5-sulfonyl-8-hydroxyquinoline has a certain solubility in water, which enhances its hydrophilicity due to the presence of sulfonyl groups. However, its solubility is also affected by factors such as temperature and pH value. In a specific pH range, its existing form changes, which in turn affects its solubility.
    Its chemical stability is also an important property. Under normal conditions, it is quite stable. However, when it encounters extreme conditions such as strong oxidants, strong acids, and strong bases, the molecular structure may be damaged, triggering chemical reactions and causing its properties to change. In short, the acidity, coordination, solubility, and chemical stability of 5-sulfonyl-8-hydroxyquinoline give it potential for application in many fields, such as chemical analysis, materials science, and biomedicine.
    What is the preparation method of 5-Sulfo-8-hydroxyquinoline?
    5-Sulfonyl-8-hydroxyquinoline is an organic compound. The preparation method is as follows:
    First, 8-hydroxyquinoline is used as the initial raw material. In the reaction vessel, carefully inject an appropriate amount of concentrated sulfuric acid. Due to the strong corrosiveness and water absorption of sulfuric acid, the operation must be cautious. Subsequently, 8-hydroxyquinoline is slowly added to the concentrated sulfuric acid, while stirring vigorously. This is to make the two fully contact and react evenly.
    The control of the reaction temperature is crucial. The temperature of the reaction system needs to be gradually raised to a specific range, generally between about 150 ° C and 200 ° C. Within this temperature range, the benzene ring in the 8-hydroxyquinoline molecule will sulfonate with concentrated sulfuric acid. The sulfonic acid group (-SOH) of concentrated sulfuric acid replaces the hydrogen atom at a specific position on the benzene ring, resulting in the formation of 5-sulfo-8-hydroxyquinoline.
    During the reaction, close attention should be paid to the reaction process. The degree of reaction can be monitored by means of thin layer chromatography (TLC). After the reaction reaches the desired level, the reaction mixture is slowly poured into a large amount of ice water. This operation is designed to quickly reduce the temperature, stop the reaction, and allow the product to precipitate from the system.
    After the resulting mixture is filtered to collect the precipitate. The precipitate is the crude product containing impurities of 5-sulfo-8-hydroxyquinoline. In order to obtain a high purity product, the crude product needs to be purified. The commonly used purification method is recrystallization. Select a suitable solvent, such as ethanol, water, etc., dissolve the crude product, heat it until it is completely dissolved, and filter it hot to remove insoluble impurities. Subsequently, the filtrate is slowly cooled, and 5-sulfo-8-hydroxyquinoline will precipitate in the form of crystals. Filtrate again, collect crystals, wash with cold solvent, dry at low temperature, and finally obtain pure 5-sulfo-8-hydroxyquinoline.
    5-Sulfo-8-hydroxyquinoline what are the precautions during use
    5-Sulfonyl-8-hydroxyquinoline, when using it, there are a number of important things that need to be paid attention to.
    First, this substance has specific chemical properties, and safety procedures must be strictly followed when operating. Because it may be corrosive and irritating, if you accidentally touch the skin or eyes, rinse with a lot of water and seek medical attention as appropriate. After use, properly dispose of the residue, do not pour it at will, and avoid polluting the environment.
    Second, when measuring and preparing the solution, it is essential to be accurate. Because of its high reactivity, the amount of dosage is often related to the effectiveness of the reaction. It is recommended to use accurate measuring tools, such as balances, pipettes, etc., to ensure accurate measurement.
    Furthermore, pay attention to its stability. 5-Sulfonyl-8-hydroxyquinoline may change under specific temperature, humidity and light conditions. Therefore, when stored in a dry, cool and dark place, to prevent deterioration, causing its performance to change, affecting the results of experiments or production.
    In addition, when using, carefully observe the pH of the reaction system. This substance exists in different pH environments and has different reactivity. Control the pH value of the reaction system to make it work best.
    Finally, study its physicochemical properties, reaction characteristics, etc. in detail before use. Know the possibility of its reaction with other substances, and take precautions in advance to avoid unexpected reactions, endangering safety, or causing failure of experiments and production.