5 Chloro 7 Iodo 8 Hydroxyquinoline
quinoline thiophene imidazole thiazole

5-Chloro-7-iodo-8-hydroxyquinoline

Taiy Chemical

    Specifications

    HS Code

    965633

    Chemical Formula C9H5ClINO
    Molecular Weight 326.497
    Appearance Solid
    Solubility In Water Low solubility, as it is an organic heterocyclic compound
    Solubility In Organic Solvents Soluble in some common organic solvents like ethanol, acetone
    Melting Point Data would need to be experimentally determined or sourced from a specific reference
    Boiling Point Requires experimental determination or literature - based reference
    Density Needs to be measured or sourced from reliable chemical databases
    Pka Value Depends on the acidic nature of the hydroxy group, would need to be determined experimentally

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    General Information
    Where to Buy 5-Chloro-7-iodo-8-hydroxyquinoline in China?
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    Frequently Asked Questions

    As a leading 5-Chloro-7-iodo-8-hydroxyquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-Chloro-7-iodo-8-hydroxyquinoline?
    5-Chloro-7-iodine-8-hydroxyquinoline is one of the organic compounds. Its main uses are quite extensive.
    In the field of chemical analysis, it is often used as an analytical reagent. Because it can react specifically with many metal ions to form complexes with specific properties. For example, after complexing with some metal ions, it will show a unique color change, which makes it useful for qualitative and quantitative analysis of metal ions. With this reaction, the content of specific metal ions in solution can be accurately identified and determined, which is of great significance in ore analysis, water quality monitoring, etc.
    In the field of medicine, it also has its uses. Studies have found that the compound exhibits certain biological activities, or has antibacterial and antiviral effects. It may interfere with the physiological process of pathogens, inhibit their growth and reproduction, and provide a potential lead compound for the research and development of new drugs.
    In the field of materials science, 5-chloro-7-iodine-8-hydroxyquinoline can participate in the synthesis of materials. Due to its special structure, it can endow materials with specific properties. For example, in some optical materials, it can improve the optical properties of materials, making it show unique application potential in optoelectronic devices, such as Light Organic Emitting Diode, which may improve the luminous efficiency and stability of devices.
    In conclusion, 5-chloro-7-iodine-8-hydroxyquinoline plays an important role in many fields such as chemical analysis, medicine and materials science. With the deepening of research, its application prospects may become broader.
    What are the physical properties of 5-Chloro-7-iodo-8-hydroxyquinoline?
    5-Chloro-7-iodine-8-hydroxyquinoline is one of the organic compounds. Its physical properties are worth exploring.
    First of all, its appearance, under normal conditions, is mostly solid state, color or white, or nearly yellowish, fine powder shape, the quality is uniform.
    As for the melting point, it is about a specific temperature range. This temperature value is one of its inherent characteristics. It is determined by the intermolecular force and structure. It is of great significance for its identification and purification. Its solubility is also characterized in specific solvents. In some organic solvents, such as alcohols and ethers, it can have certain solubility, but in water, it has limited solubility. This difference in solubility is due to the interaction between the polarity of the compound and the polarity of the solvent.
    Furthermore, its density is also the key to physical properties. The value of density reflects the relationship between its mass and volume. Compared with similar compounds, it can help to distinguish the degree of molecular accumulation and structural compactness.
    In addition, the vapor pressure of 5-chloro-7-iodine-8-hydroxyquinoline is very small, and it has a small tendency to evaporate under normal temperature and pressure. This property is due to the strong interaction between molecules, which makes it difficult to convert from the liquid phase to the gas phase. < Br >
    Its refractive index also has characteristics. When light passes through the substance, the degree of refraction varies according to its structure and composition. This parameter may be useful in optical related research and applications.
    In summary, the physical properties of 5-chloro-7-iodine-8-hydroxyquinoline have their own reasons, and are of great significance in chemical research, materials science and other fields. It can help researchers to clarify its characteristics and lay the foundation for related applications.
    What is the chemistry of 5-Chloro-7-iodo-8-hydroxyquinoline?
    5-Chloro-7-iodine-8-hydroxyquinoline, this is an organic compound. Its chemical properties are unique and have general characteristics.
    When it comes to acidity and alkalinity, 8-hydroxyquinoline is weakly acidic, and its hydroxyl group can release protons. In 5-chloro-7-iodine-8-hydroxyquinoline, the substitution of chlorine and iodine has a slight impact on acidity. Halogen atoms have electron-absorbing effect, which can make hydroxyhydrogen more easily dissociated and slightly increase acidity.
    Its redox property is also worth exploring. The 8-hydroxyquinoline structure can be oxidized. In 5-chloro-7-iodine-8-hydroxyquinoline, the electron cloud density of the hydroxyl o-para-position is changed due to halogen substitution. In the oxidation reaction, its activity and check point selectivity are different from those of the unsubstituted. Under specific conditions, it can be oxidized to quinones and other products.
    In terms of solubility, the compound is insoluble in water because its molecules are non-polar or weakly polar. However, it can be soluble in some organic solvents, such as ethanol, acetone, chloroform, etc. This property is related to the hydrophobic quinoline ring and halogen atoms in the molecular structure. Organic solvents can interact with molecules by van der Waals force to dissolve them.
    In coordination chemistry, 5-chloro-7-iodine-8-hydroxyquinoline is a potential ligand. 8-hydroxyquinoline can be coordinated with metal ions by hydroxyl oxygen and nitrogen atoms to form stable complexes. The introduction of chlorine and iodine changes the spatial structure and electron cloud distribution of ligands, affecting their coordination ability and mode with metal ions. Or it can form complexes with diverse structures, which have potential applications in catalysis, materials science and other fields.
    In addition, its stability also needs to be considered. Under normal conditions, the compound is relatively stable. However, in case of high temperature, strong light or specific chemical reagents, decomposition and substitution reactions may occur. When the temperature is high, the carbon-halogen bond may be broken; when the strong light is irradiated, the electron transition in the molecule may be induced, which triggers a photochemical reaction.
    What are 5-Chloro-7-iodo-8-hydroxyquinoline synthesis methods?
    For the synthesis of 5-chloro-7-iodine-8-hydroxyquinoline, there are many methods in the past. One method is to take 8-hydroxyquinoline as a group and make it react with an appropriate halogenated reagent. If you want to introduce a chlorine atom, you can choose a chlorine-containing reagent and make it substitution with a specific position in 8-hydroxyquinoline under suitable reaction conditions. This reaction must pay attention to the reaction temperature, reaction duration and the proportion of reagents. If the temperature is too high or too low, it may affect the process of the reaction and the yield of the product. If the duration is too short, the reaction may not be fully functional; if it is too long, it may produce side reactions.
    As for the introduction of iodine atoms, a similar method is followed. Appropriate iodine-containing reagents are used to react with chlorinated products under appropriate conditions. The choice of solvent is also crucial, and different solvents affect the reaction rate and selectivity. For example, some polar solvents may promote the reaction, making halogen atoms more susceptible to substitution.
    There are other methods, or the specific functional group of 8-hydroxyquinoline can be modified first to change its electron cloud density, and then the halogenation reaction can be carried out. In this way, chlorine and iodine atoms can be more accurately replaced in the target position, improving the purity and yield of the product. However, these methods require fine control of the reaction conditions, and also require the purity of the reactants and the cleanliness of the reaction device. A little carelessness may cause the reaction to deviate from expectations, produce impurities, and affect the quality of the product. The synthesis process needs to be handled carefully and paid attention to step by step to obtain pure 5-chloro-7-iodine-8-hydroxyquinoline.
    5-Chloro-7-iodo-8-hydroxyquinoline what are the precautions during use
    5-Chloro-7-iodine-8-hydroxyquinoline is also a chemical substance. When using it, there are several ends to pay attention to.
    First, it has certain chemical activity, and you must pay attention to protection when contacting it. This substance may cause irritation to the skin, eyes and respiratory tract. Therefore, when using it, wear appropriate protective equipment, such as gloves, goggles and gas masks, to prevent direct contact with it and cause damage to the body.
    Second, 5-chloro-7-iodine-8-hydroxyquinoline is also particular about storage. It should be placed in a dry, cool and well-ventilated place, away from fire, heat and strong oxidants. Due to its chemical properties, improper storage environment may cause chemical reactions, damage quality, and even cause safety accidents.
    Furthermore, during use, the dosage should be precisely controlled. Excessive use not only increases costs, but also causes unexpected situations in subsequent reactions or applications. It needs to be used according to specific experimental purposes or production requirements, and according to accurate measurement methods.
    In addition, when 5-chloro-7-iodine-8-hydroxyquinoline participates in chemical reactions, reaction conditions such as temperature and pH have a great impact on the reaction process and products. Therefore, during operation, the reaction conditions must be strictly controlled to ensure that the reaction proceeds in the expected direction and achieves the desired result.
    At the end of the use, the disposal of its waste cannot be ignored. It must follow relevant environmental regulations and dispose of it in a proper manner. It must not be discarded at will to avoid pollution to the environment.