5 Amino 8 Hydroquinoline Dihydrochloride
quinoline thiophene imidazole thiazole

5-Amino-8-Hydroquinoline Dihydrochloride

Taiy Chemical

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    HS Code

    785199

    Chemical Name 5 - Amino - 8 - Hydroquinoline Dihydrochloride

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    General Information
    Where to Buy 5-Amino-8-Hydroquinoline Dihydrochloride in China?
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    Frequently Asked Questions

    As a leading 5-Amino-8-Hydroquinoline Dihydrochloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 5-amino-8-hydroxyquinoline dihydrochloride?
    5-Hydroxy-8-methoxypsoralen dicarboxylic anhydride is one of the organic compounds. It has unique chemical properties.
    This compound has certain lipophilic properties. It has moderate solubility in organic solvents, such as ethanol and chloroform, but low solubility in water. In its chemical structure, the presence of hydroxyl groups and methoxy groups makes it have specific reactivity. Hydroxyl groups can participate in many chemical reactions, such as esterification reactions, and can interact with acid compounds to form corresponding ester products. In this process, the hydrogen atom of the hydroxyl group is replaced by acid groups to form new compounds with different properties.
    Furthermore, the structure of psoralen makes it photochemically active. When exposed to specific wavelengths of light, photochemical reactions occur, which have potential applications in the fields of medicine and materials science. For example, in the study of photodynamic therapy, its photochemical activity can be used to target specific cells or tissues.
    The dicarboxylic anhydride is partially chemically active and easily reacts with nucleophiles. When exposed to water, hydrolysis can occur, and the structure of the dicarboxylic anhydride is opened to form the corresponding dicarboxylic acid. When reacted with alcohols, ester anhydrides or diacid ester compounds can be formed. This reaction provides an important way for the construction of complex organic molecular structures in organic synthesis.
    In addition, the chemical properties of the compound are also affected by the surrounding chemical environment. Different substituents and molecular spatial configuration changes may have significant effects on their reactivity, solubility and other properties. Therefore, in research and application, various factors need to be carefully considered to accurately grasp their chemical behavior.
    What are the main uses of 5-amino-8-hydroxyquinoline dihydrochloride?
    5-Amino-8-hydroxyquinoline-2,4-diketoanhydride has many main uses.
    In the field of medicine, this compound shows unique effects. Due to its special structure, it can be used as a potential drug intermediate. After specific chemical reactions, it can construct a molecular framework with biological activity for the development of new antibacterial drugs. Due to the special physiological structure and metabolic pathway of bacteria, this compound can specifically interfere with key physiological processes of bacteria, such as cell wall synthesis, protein transcription, etc., for the purpose of antibacterial. And in the exploration of anti-cancer drugs, it also has certain potential. Or it can induce tumor cell apoptosis and inhibit tumor cell proliferation by regulating the signaling pathway of tumor cells.
    In the field of materials science, 5-amino-8-hydroxyquinoline-2,4-diketoanhydride is also useful. It can be used as an organic ligand to coordinate with metal ions to form metal-organic complexes. Such complexes often have unique optical and electrical properties. For example, it can be used to prepare luminescent materials and applied to organic Light Emitting Diode (OLED) technology. It can emit light efficiently under the action of electric fields and has high color purity, providing new material options for the development of display technology. At the same time, in terms of sensor materials, it has the ability to selectively identify specific analytes. Sensitive detection of harmful substances in the environment and specific biomarkers in organisms can be achieved by virtue of the optical or electrical changes caused by the binding of analytes.
    In the field of chemical synthesis, this compound is often used as an important starting material. Its rich reaction check points can be derived from various reactions such as nucleophilic substitution and electrophilic substitution. Chemists can construct complex and novel organic molecules by precisely modifying their structures, contributing to the development of organic synthetic chemistry and helping to synthesize more organic compounds with special functions and properties.
    What is the synthesis method of 5-amino-8-hydroxyquinoline dihydrochloride?
    The synthesis of 5-amino-8-hydroxyquinoline-2,4-dicarboxylic anhydride is an important technique in organic synthesis. The method is as follows:
    First, appropriate quinoline derivatives are used as starting materials. 8-hydroxyquinoline is often taken as the initial reactant, because its structure already has quinoline ring and hydroxyl group, which lays the foundation for subsequent reactions.
    Next, the amination reaction is carried out for the 5-position of 8-hydroxyquinoline. This step often requires the help of specific amination reagents, such as ammonia derivatives, and needs to be carried out under suitable reaction conditions. The pH, temperature and reaction time of the reaction environment all have a great impact on the effectiveness of the amination reaction. Generally speaking, the alkaline environment is conducive to the introduction of amino groups, and moderate increase in temperature can speed up the reaction rate. However, too high temperature may also cause side reactions to breed.
    After the synthesis of 5-amino-8-hydroxyquinoline, the structure of dicarboxylic acid anhydride is constructed. This step is often achieved by reacting with reagents with carboxylic groups. Usually, diacid derivatives are used as raw materials, and under the action of dehydrating agents, the dehydration and condensation of carboxylic acids occurs, thereby forming acid anhydride structures. Commonly used dehydrating agents include acetic anhydride, phosphorus oxychloride, etc. This reaction also requires fine regulation of reaction conditions, and precise control of temperature and reagent dosage is indispensable. If the temperature is too low, the reaction is difficult to advance; if the temperature is too high, the formed structure may be destroyed.
    During the synthesis process, each step of the reaction requires separation and purification of the product to ensure the purity of the raw materials for the next reaction. Commonly used separation and purification methods include recrystallization and column chromatography. Recrystallization purifies the product by means of differences in the solubility of the product in the solvent at different temperatures; column chromatography achieves the separation of each component according to the different distribution coefficients between the stationary phase and the mobile phase.
    After such a series of carefully designed and operated reaction steps, 5-amino-8-hydroxyquinoline-2,4-dicarboxylic anhydride can be obtained. However, the success or failure of the synthesis depends entirely on the precise control of the reaction conditions and the strict purification of the products in each step. With a little carelessness, it is difficult to obtain the ideal product.
    What are the precautions for 5-amino-8-hydroxyquinoline dihydrochloride in storage and transportation?
    5-Amino-8-hydroxyquinolinedione anhydride is a chemical substance. When storing and transporting, many matters need to be paid attention to.
    First word storage. Its nature may be more active, so it should be placed in a cool, dry and well-ventilated place. It must not be placed in a high temperature or humid environment, because high temperature can easily cause chemical reactions and cause it to deteriorate; humid gas may cause it to absorb moisture, affecting its purity and quality. Furthermore, it should be stored separately from oxidants, reducing agents, acids, bases and other substances. Contact with these substances may cause violent reactions, or even risk explosion. In the place of storage, there should also be corresponding fire and leakage emergency treatment equipment for emergencies.
    As for transportation, appropriate packaging materials should be selected. The packaging used must be sturdy and can effectively prevent its leakage and scattering. The outside of the package should be clearly marked with its name, nature, danger warning and other information so that the transportation personnel and regulators can know. During transportation, the speed of the vehicle should not be too fast to avoid bumps and vibrations to prevent damage to the packaging. The transportation tool should also be kept clean and dry, and no substances that can react with it should be left. And the transportation personnel must be professionally trained to be familiar with its characteristics and emergency treatment methods. If a leak occurs during transportation, corresponding measures should be taken immediately to evacuate the surrounding people to prevent the spread of pollution, and timely report to the relevant departments for handling according to professional guidance. In this way, the safety of 5-amino-8-hydroxyquinolinedione anhydride during storage and transportation can be guaranteed, and accidents can be avoided.
    What is the market price of 5-Amino-8-hydroxyquinoline dihydrochloride?
    In today's world, in the market, the price of 5-amino-8-hydroxyquinoline diketonate cannot be determined immediately. The change in its price is related to all things, and it cannot be determined.
    First, it is related to the supply and demand of this product. If there are many people in the market who want it, but there are few people who produce it, the price will rise; if the supply exceeds the demand, the stock is difficult to sell, and the price will fall. At present, those who use this 5-amino-8-hydroxyquinoline diketonate may need it in various industries, such as medical medicine and pharmaceuticals, or in the manufacture of industrial equipment. The amount of demand changes from time to time, and the price also changes.
    Second, the cost of making this product is also the main reason. The choice of materials and the cost of labor are all related to the price. If the source of materials is scarce, the cost of manufacturing will be high, and the price will be difficult to drop. Or the new technology can make it easier and cheaper to make, and the price may drop.
    Third, the change of the world situation can also move the price. The trade of the four sides and the regulation of taxes can be affected. There is no stagnation in trade, and the tax is fair, so the price may be stable; if there is a hindrance to trade and the tax increases, the price will be impacted.
    From this perspective, the market price of 5-amino-8-hydroxyquinoline diketonate is often uncertain due to changes in supply and demand, changes in costs, and changes in the world situation. To know its exact price can only be obtained when considering the situation and observing changes in everything.