5 7 Dichloro 1 2 3 4 Tetrahydroisoquinoline 6 Carboxylic Acid
quinoline thiophene imidazole thiazole

5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

Taiy Chemical

    Specifications

    HS Code

    768324

    Chemical Formula C10H9Cl2NO2
    Molecular Weight 246.09
    Appearance Solid (predicted)
    Boiling Point 437.2°C at 760 mmHg (predicted)
    Melting Point 180 - 185°C
    Density 1.458 g/cm³ (predicted)
    Logp 2.76 (predicted)
    Pka 3.78 (predicted)
    Solubility Soluble in organic solvents like DMSO
    Stability Stable under normal conditions

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    General Information
    Where to Buy 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid in China?
    As a trusted 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid?
    5% 2C7-dioxy-1% 2C2% 2C3% 2C4-tetrahydroisoquinoline-6-carboxylic acid, its chemical properties are quite unique. This compound has a certain acidity, because it contains carboxyl groups, which can be dissociated from hydrogen ions under suitable conditions.
    In the field of organic synthesis, it is often used as a key intermediate. The presence of heterocyclic and carboxyl groups in its molecular structure gives it a variety of reactivity. For example, carboxyl groups can be esterified with alcohols to form ester derivatives. This reaction requires acid catalysis and is easier to carry out under heating conditions.
    At the same time, its heterocyclic structure is also reactive. The hydrogen atom on the ring can be replaced by a variety of functional groups. Through electrophilic substitution, groups such as halogen atoms and alkyl groups are introduced to expand its chemical diversity and construct more complex organic molecular structures.
    Furthermore, 5% 2C7-dioxy-1% 2C2% 2C3% 2C4-tetrahydroisoquinoline-6-carboxylic acid Under alkaline conditions, the carboxyl group can neutralize with the base to form the corresponding carboxylate. This salt may have unique application value in some organic synthesis or drug development. In short, the compound shows important chemical properties and application potential in many fields of organic chemistry due to its own structural characteristics.
    What are the synthesis methods of 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid?
    To prepare 5% 2C7-dioxy-1% 2C2% 2C3% 2C4-tetrahydroisoquinoline-6-carboxylic acid, there are many methods, which are now several common methods.
    First, with suitable starting materials, it is formed by multi-step reaction. First, the starting material undergoes a specific substitution reaction and key functional groups are introduced. This substitution reaction requires appropriate reaction conditions, such as suitable temperature and catalyst, to make the reaction proceed smoothly. Then, after cyclization, the core structure of isoquinoline is constructed. This step also requires careful regulation of reaction parameters to ensure the selectivity and yield of cyclization. Then, the oxidation reaction is carried out at a specific location to achieve the target structure of dioxygen. This oxidation step requires precise control of the amount of oxidant and reaction time to prevent excessive oxidation.
    Second, the strategy of biomimetic synthesis can be used. Simulate the chemical reaction mechanism in the organism, and use enzymes or biocatalysts to promote the reaction. This approach often has the advantages of mild reaction conditions and high selectivity. First find a biocatalyst that is compatible with the target reaction, and then in a suitable reaction system, the substrate is gradually converted into the target product under the action of the biocatalyst. This process requires strict control of the activity, stability of the biocatalyst, and the pH value and temperature of the reaction system.
    Third, the method of transition metal catalysis is used. Transition metal catalysts are widely used in organic synthesis and can effectively catalyze many complex reactions. Select suitable transition metal catalysts, such as palladium, copper, etc., with specific ligands, so that the starting materials can undergo coupling reactions and cyclization reactions under their catalysis. The key to this method is to optimize the combination of catalysts and ligands, and to precisely adjust the reaction conditions to improve the efficiency and selectivity of the reaction.
    All these methods have advantages and disadvantages. In actual synthesis, the appropriate synthesis method needs to be carefully selected according to the availability of starting materials, the difficulty of the reaction, cost considerations, and the purity requirements of the target product.
    In which fields is 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid used?
    5,7-Dioxy-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid, which has a wide range of uses. In the field of medicine, it is often used as a key intermediate to help synthesize many bioactive compounds. Some of the drugs synthesized from this raw material have outstanding performance in the treatment of nervous system diseases, or can regulate neurotransmitters, or can affect nerve cell metabolism, bringing hope for the conquest of Parkinson's, Alzheimer's and other diseases.
    In the field of organic synthesis, 5,7-dioxy-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid has become the cornerstone of building complex organic molecules due to its unique structure. Chemists can modify their structures through a variety of chemical reactions to synthesize many organic materials with novel structures and specific properties. These materials may exhibit excellent optical and electrical properties in the field of optoelectronics, such as for the manufacture of new Light Emitting Diodes, solar cells, etc.
    In the field of materials science, the materials derived from it can exhibit unique physical and chemical properties under specific conditions, and can be used to prepare adsorption materials with high selective identification ability for specific substances. It plays an important role in environmental monitoring, material separation, etc.
    In addition, in biochemical research, it can also be used as a tool molecule to assist in the exploration of complex biochemical processes in organisms, helping scientists to better understand the mysteries of life. In conclusion, 5,7-dioxy-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid has important applications in many fields, and its potential value is expected to be further explored with the deepening of research.
    What is the market outlook for 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid?
    5,7-Dibromo-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid, the market prospects are as follows.
    Looking at the field of pharmaceutical chemical industry today, this compound has potential opportunities. At the end of drug development, its structure is unique, and it may be a key building block for the creation of novel drug molecules. Because of its special chemical structure, it may be able to fit with specific targets in organisms, and then exhibit unique biological activities, such as anti-tumor, neuroprotective and other pharmacological effects. In this regard, medical researchers are actively exploring its activity and mechanism. If there is a breakthrough, it will surely lead to the generation of new specific drugs, and its market demand will also surge.
    In the field of chemical materials, 5,7-dibromo-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid may be used as a raw material for the synthesis of special functional materials. With it as a starting material, after specific chemical reactions, materials with unique optical and electrical properties may be constructed, and are used in emerging fields such as organic Light Emitting Diodes and sensors. With the rapid development of science and technology, the demand for characteristic materials in these fields is increasing, so this compound also has considerable development space.
    However, its market expansion also faces challenges. The complexity and cost control of the synthesis process are key challenges. If the synthesis process is complicated and expensive, its large-scale production and application will be limited. In addition, the competition of similar alternative compounds cannot be ignored. Only by continuously optimizing the synthesis process, improving product quality, and reducing production costs can we stand out in the market competition and enjoy broad prospects.
    Precautions in the preparation of 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid
    To prepare 5,7-dioxy-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid, the following things should be paid attention to:
    First, the selection and pretreatment of raw materials are the key. The raw materials used must have high purity, and impurities will seriously interfere with the reaction process and product purity. If some raw materials need to be finely purified to remove possible isomers or other impurities, they can be used in the reaction, otherwise side reactions will occur, and the yield and purity of the product will decrease.
    Second, precise control of the reaction conditions is indispensable. Temperature, pressure, reaction time and catalyst dosage all have a profound impact on the reaction. This reaction is sensitive to temperature. If the temperature is too high, the side reactions will intensify, and the product will decompose or form other by-products. If the temperature is too low, the reaction rate will be slow, time-consuming, and the yield will also be affected. The pressure also needs to be strictly controlled. The appropriate pressure ensures that the reaction proceeds in the expected direction. If the pressure is inappropriate or the reaction cannot occur, or adverse side reactions will occur. The amount of catalyst is also particular. If the dosage is too small, the catalytic effect will be poor, and the reaction will be difficult to start or the rate will be slow. If the dosage is too large, it may cause unnecessary side reactions, and may also increase the difficulty of product separation.
    Third, the monitoring of the reaction process is of great significance. Real-time monitoring of the reaction process by means of thin-layer chromatography (TLC) and high-performance liquid chromatography (H According to the monitoring results, the reaction conditions can be flexibly adjusted. If the reaction is found to be too slow, or the temperature is appropriately increased and the catalyst is added; if too many side reactions are detected, or the temperature is reduced and the proportion of the reactants is adjusted.
    Fourth, the separation and purification of the product is quite complicated. After the reaction is completed, the reaction system may contain unreacted raw materials, by-products and target products. High-purity products can be obtained by using a variety of separation techniques such as extraction, distillation, column chromatography, etc. During extraction, a suitable extractant is selected to ensure the effective transfer of the target product to the organic phase; during distillation, the temperature and pressure are precisely controlled to achieve the separation of substances with different boiling points; during column chromatography, the fixed phase and mobile phase are reasonably selected to effectively separate the target product and impurities.
    Fifth, safety protection must not be sparse. The reagents used in the reaction may be toxic, corrosive and flammable. When operating, be sure to wear protective clothing, gloves and goggles and other protective equipment. Operate in a well-ventilated environment to avoid the accumulation of toxic and harmful gases. Properly dispose of waste and dispose of it in accordance with relevant regulations. Do not discharge it at will to avoid polluting the environment.