What is the chemical structure of (4S) -10- [ (dimethylamino) methyl] -4-ethyl-4,9-dihydroxy-1H-pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-3,14 (4H, 12H) -dione hydrochloride (1:1)

(This is a description of the chemical structure, and the following attempt is to interpret it in the classical Chinese style of "Tiangong Kaiwu")

Looking at this, its chemical structure is quite complex. (4S) -10- [ (dimethylhydroxymethyl) methyl] -4-ethyl-4,9-difluoro-1H-diazolo [3 ', 4': 6,7] Indolicino [1,2-b] Pyran-3,14 (4H, 12H) -diketoglutaric acid (1:1) structure.

Where the groups are linked to each other, (4S) seems to be a configuration identification, 10 or a serial number of a certain position. [ (dimethyl hydroxymethyl) methyl], dimethyl is connected to hydroxymethyl and is connected to methyl, which has a delicate structure. 4-Ethyl indicates that ethyl is connected to the fourth position. 4,9-Difluoro, that is, there are fluorine atoms at the fourth and ninth positions. 1H-to-azolo, etc. are a combination of specific cyclic structures, and the rings are joined in a specific way, like tenon and mortise. 3,14 (4H, 12H) -diketoglutaric acid (1:1), showing the presence of diketone structures at positions 3 and 14, and associated with glutaric acid in a ratio of 1:1, seems to play a key stabilizing or reactive role in the entire structure. The combination of such various groups and structures constitutes this unique chemical structure. In the field of chemistry, it is just like the quirk of creation, where the parts complement each other and form a wonderful chemical entity.

What are the physical properties of (4S) - 10 - [ (dimethylamino) methyl] - 4 - ethyl - 4,9 - dihydroxy - 1H - pyrano [3 ', 4': 6,7] indolicino [1,2 - b] quinoline - 3,14 (4H, 12H) -dione hydrochloride (1:1)

This is a rather complex prescription, which contains many ingredients, each of which has unique physical properties.

In the formula " (4S) -10- [ (dimethylhydroxymethyl) methyl] -4-ethyl-4,9-difluoro-1H-tetronaphthalene [3 ', 4': 6,7] phendirixine [1,2-b] square acid-3,14 (4H, 12H) -diketonaphthalene naphthalate (1:1) ". In this compound, due to the presence of multiple different groups, it exhibits specific physical properties. In terms of morphology, its structure is complex, or it is a crystalline solid. In terms of solubility, due to the presence of both polar hydroxyl and carboxyl groups in the molecule, as well as non-polar hydrocarbon structures, the solubility may be different in polar and non-polar solvents. Some organic solvents such as ethanol and acetone may have a certain solubility, while the solubility in water may be relatively limited.

From the perspective of melting point, the complex molecular structure makes the intermolecular forces diverse, and its melting point may be high, requiring a specific temperature to melt. In addition, there is a conjugate system in the compound, which has optical properties or certain absorption spectral characteristics. Under specific wavelengths of light, or has a unique absorption peak, which can be used for spectral analysis and identification. At the same time, due to special atoms such as fluorine, they will also present unique signals in spectroscopic analysis such as nuclear magnetic resonance, which helps to determine their structure.

What is the use of (4S) - 10 - [ (dimethylamino) methyl] - 4 - ethyl - 4,9 - dihydroxy - 1H - pyrano [3 ', 4': 6,7] indolicino [1,2 - b] quinoline - 3,14 (4H, 12H) -dione hydrochloride (1:1)

(4S) -10- [ (dimethylhydroxyl) methyl] -4-ethyl-4,9-difluoro-1H-tropic [3 ', 4': 6,7] phenidinrisine [1,2-b] pyran-3,14 (4H, 12H) -diketoglutaric acid (1:1) This drug can be used for a variety of diseases.

Looking at its structure, it is a complex organic compound. Such compounds are often used in the field of medicine to demonstrate their effectiveness. Or they can interact with specific targets in organisms by virtue of their unique chemical structure, thereby regulating physiological processes and healing diseases.

According to the past medical research on various organic drugs, such fluorine-containing and polycyclic structures may have affinity for specific enzymes and receptors. Such as (4S) -10- [ (dimethylhydroxyl) methyl] -4-ethyl-4,9-difluoro-1H-directional [3 ', 4': 6,7] phenidinrisine [1,2-b] pyran-3,14 (4H, 12H) -diketoglutaric acid (1:1), or can precisely act on certain cell signaling pathways and intervene in disease process.

In modern medicine, such drugs may be used to fight tumors, and their structure binds to specific targets of cancer cells to inhibit the proliferation of cancer cells and induce their apoptosis; or they can be used as drugs for neurological diseases to regulate neurotransmitter transmission and repair damaged nerve cells. Although its use has not been detailed in conclusive medical records, according to its chemical properties, it can be deduced to the broad prospects of medicine, and it is expected to open up new avenues for the treatment of many diseases.

What is the synthesis method of (4S) - 10 - [ (dimethylamino) methyl] - 4 - ethyl - 4,9 - dihydroxy - 1H - pyrano [3 ', 4': 6,7] indolicino [1,2 - b] quinoline - 3,14 (4H, 12H) -dione hydrochloride (1:1)

To prepare (4S) -10- [ (dimethyl hydroxyl) methyl] -4-ethyl-4,9-difluoro-1H-to-azolo [3 ', 4': 6,7] indolicine [1,2-b] pyran-3,14 (4H, 12H) -diketone (1:1), the method is as follows:

First take an appropriate amount of starting material, which must have a specific structure, containing (4S) related configurations and many specific groups, such as [ (dimethyl hydroxyl) methyl] at position 10, ethyl at position 4, difluoro at position 4, and so on. < Br >
In a suitable reaction vessel, add this raw material, and then add various reagents and catalysts according to the appropriate reaction sequence and ratio. The reaction conditions are very critical, and the temperature, pressure and reaction time need to be precisely regulated. The temperature may need to be maintained in a specific range, and the pressure must also be adapted to ensure the smooth and efficient progress of the reaction.

During the reaction process, specific chemical reactions occur between each group, and the complex structure of the target product is gradually constructed through steps such as bonding and bond breaking. Or some groups interact first to form an intermediate product, which is then further reacted to finally form (4S) -10- [ (dimethyl hydroxyl) methyl] -4-ethyl-4,9-difluoro-1H-to-zolo [3 ', 4': 6,7] indolicine [1,2-b] pyran-3,14 (4H, 12H) -diketoic acid ketone (1:1).

After the reaction is completed, it still needs to be separated and purified. Or use chromatography, crystallization, etc., to remove impurities and obtain high-purity target products. Therefore, the method of synthesis of this compound is obtained.

(4S) - 10 - [ (dimethylamino) methyl] - 4 - ethyl - 4,9 - dihydroxy - 1H - pyrano [3 ', 4': 6,7] indolicino [1,2 - b] quinoline - 3,14 (4H, 12H) -dione hydrochloride (1:1) What are the relevant safety precautions?

(4S) - 10 - [ (dimethylhydroxymethyl) methyl] - 4 - ethyl - 4,9 - difluoro - 1H - naphthaleno [3 ', 4': 6,7] naphthaleno [1,2 - b] furan - 3,14 (4H, 12H) - diketonate ketone (1:1) There are many safety precautions related to this product and it is necessary to treat it with caution.

First, the operation must be in a well-ventilated environment, because it may evaporate harmful gases. If it is in a closed space, the gas accumulation is easy to cause poisoning. For example, "Tiangong Kaiwu" says: "Where the mirror is cast, the mold is made of gray sand, and the copper is made of tin, and it is cast in an open place to prevent air stuffiness." The same is true. Ventilation is to ensure the health of the operator.

Second, strictly follow the operating procedures to precisely control the dose and reaction conditions. The reaction of this compound is complex and sensitive. If there is a slight difference, such as temperature and pH inconsistency, it is easy to cause the reaction to go out of control and cause danger. As the ancient books say: "The method of pharmacy, if it is balanced, is not bad at all."

Third, take protective measures and wear protective clothing, gloves, goggles, etc. This compound may be corrosive and irritating, and contact with the skin and eyes can cause burns. In the past, there were craftsmen who were not well protected and were injured by poisons. It was too late to regret.

Fourth, properly store it in a cool, dry and ventilated place, away from fire sources and oxidants. Due to its nature or activity, improper storage is prone to fire and explosion. "Tiangong Kaiwu" also emphasizes the method of storage. It is said that "the warehouse of hidden objects should be dry and avoid water and fire".

Fifth, waste disposal should be in compliance and should not be discarded at will. Because it may contain harmful substances, pollute the environment and endanger the ecology. It must be handled by a professional organization according to the prescribed process to ensure the safety of the environment.