(4S)-10-amino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

(4S) -10-amino-4-ethyl-4-hydroxy-1H-pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-3,14 (4H, 12H) -dione is an organic compound with complex structure. Its chemical structure is composed of many specific groups and ring system ingeniously linked.
Looking at its structure, the main body contains a fused polycyclic system. Among them, the pyran ring is fused with the indolicino ring and the quinoline ring, and this fused ring system endows the compound with unique spatial configuration and chemical activity. The presence of ethyl and hydroxyl groups in the 4 positions of the pyran ring can significantly affect the physical and chemical properties of the molecule, such as hydrophilicity and steric hindrance. The amino group at position 10 is a reactive group that can participate in a variety of chemical reactions, such as salting with acids and reacting with acylating reagents. The diketone structures at positions 3 and 14 introduce conjugated systems into the molecule, which affects the electron cloud distribution and spectral properties of the compound.
The unique structure of this compound may make it have specific biological activity, which may have potential application value in the field of medicinal chemistry. It can be used as a lead compound. Structural modification and optimization are used to explore new drugs with better pharmacological activity.

(4S) -10 -Amino-4-ethyl-4-hydroxy-1H-pyrano [3 ', 4': 6,7] indolo [1,2-b] quinoline-3,14 (4H, 12H) -dione, which is an organic compound with a complex structure. Its main physical properties are as follows:
- ** Appearance properties **: or in the state of crystalline powder, which is a common form of many such structural organic compounds. Due to the intermolecular force, it forms a regularly arranged crystal structure, and then presents a powder shape. < Br > - ** Melting point **: Due to the specific molecular structure and intermolecular forces, it has a specific melting point, but the exact value needs to be accurately determined by experiments. Interactions such as hydrogen bonds and van der Waals forces between molecules determine the energy required to convert from solid to liquid, that is, the melting point.
- ** Solubility **: In organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), or exhibit some solubility. Because its molecular structure contains polar groups and non-polar parts, polar groups can interact with organic solvents to help them dissolve; while non-polar parts also interact with non-polar regions of organic solvents. However, the solubility in water may be poor. Due to the relatively strong hydrophobicity of the overall structure, the force between water molecules and compound molecules cannot match the force between compound molecules.
- ** Stability **: Under normal environmental conditions, it has certain stability. In case of extreme conditions such as strong acid, strong base or high temperature, the structure may change. Due to the existence of multiple conjugated systems and sensitive chemical bonds in its structure, strong acids and strong bases can cause protonation or deprotonation reactions and destroy the original chemical bonds; high temperature can provide enough energy to trigger reactions such as intramolecular rearrangement and decomposition.

(4S) -10-amino-4-ethyl-4-hydroxy-1H-pyrano [3 ', 4': 6,7] indolicidino [1,2-b] quinoline-3,14 (4H, 12H) -dione, which is a complex organic compound. It may have potential utility in the field of pharmaceutical research and development. The unique structure of Gain, or it can interact with specific biological targets, has emerged in the treatment of diseases. For example, in the exploration of anti-tumor drugs, the structure of such compounds may interfere with key physiological processes of tumor cells, such as proliferation and metastasis, and then become powerful candidates for conquering tumors. < Br >
In the field of medicinal chemistry research, it may be a key template for the design of new drug molecules. Chemists can skillfully modify and modify according to its structure to optimize pharmacological properties, such as enhancing drug activity, enhancing selectivity, reducing toxic and side effects, etc., paving the way for the creation of better drugs.
In the field of natural product chemistry, if this compound is derived from nature, in-depth research on it may reveal the mystery of biosynthetic pathways, which will help to bionic synthesis, increase yield, and also help to understand the chemical processes in vivo. In short, although its application is still being explored, it has begun to show potential value in many scientific research fields, and is expected to bring breakthroughs and innovations.

The synthesis of (4S) -10-amino-4-ethyl-4-hydroxy-1H-pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-3,14 (4H, 12H) -dione is a delicate and complex process.
When starting, when starting with suitable raw materials. An indolicidine derivative with a specific structure can be selected as the starting material, and this material needs to have an activity check point for subsequent reactions.
Then, the hydroxylation reaction is carried out. In this step, suitable hydroxylating reagents, such as specific metal oxide complexes or hydroxyl-containing organic reagents, should be selected. The reaction conditions are quite critical. The temperature should be controlled in the range of low temperature to medium temperature, between about -20 ° C and 50 ° C, and it needs to be protected by inert gas to ensure the accuracy and efficiency of the reaction, so that the hydroxyl group is introduced at a specific position to achieve (4S) -10-amino-4-ethyl-4-hydroxy-1H-pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-3,14 (4H, 12H) -dione structure of 4-hydroxy group.
Furthermore, the amination reaction is carried out. Ammonization reagents can be used, such as the combination of liquid ammonia and sodium metal, or specific organic amination reagents. When the reaction environment is alkaline, the amino group can be successfully replaced by the corresponding check point group to form a 10-amino structure. This reaction may need to be properly heated, or at a temperature of 50 ° C to 100 ° C, and completed in a closed and dry system to prevent the growth of side reactions.
Finally, the structure of pyrano and diketone is constructed. This step requires the use of a condensation reaction to condensate compounds with active groups such as hydroxyl and amino groups with carbonyl groups. A specific acid catalyst can be selected, such as p-toluenesulfonic acid, under the condition of heating and reflux, to promote the cyclization of molecules to form pyrano [3 ', 4': 6,7] indolicino [1,2 - b] quinoline-3,14 (4H, 12H) -dione complete structure. After each step of the reaction, fine separation and purification are required, such as column chromatography, recrystallization and other means to ensure the purity of the product, and the final target product (4S) -10-amino-4-ethyl-4-hydroxy-1H-pyrano [3 ', 4': 6,7] indolicino [1,2-b] quinoline-3,14 (4H, 12H) -dione.

(4S) -10-amino-4-ethyl-4-hydroxy-1H-pyrano [3 ', 4': 6,7] indolicidino [1,2-b] quinoline-3,14 (4H, 12H) -dione, which is a complex organic compound. Looking at its structure, many special functional groups are integrated, or therefore endow it with unique biological activities.
In previous studies, compounds containing pyran and quinoline structures often have various biological activities, such as antibacterial, anti-inflammatory, and anti-tumor. The structure of pyrano-indolicidine-quinoline of this compound may make it play an important role in specific biological processes. 10-Amino and 4-hydroxyl groups can participate in the formation of hydrogen bonds, affect the interaction between compounds and biological macromolecules, or enhance the specificity and affinity of binding to receptors. The presence of
4-ethyl group, or changing the hydrophobicity and spatial conformation of molecules, has a significant impact on its transmembrane transport and binding mode to targets. The 3,14-dione structure, or a chemical reaction activity check point, participates in redox or nucleophilic addition reactions, and may initiate a series of biochemical processes in vivo.
However, only based on structural speculation, its exact biological activity still needs to be experimentally verified. It may be possible to observe its effects on the growth, proliferation and apoptosis of different cell lines through cell experiments to explore anti-tumor, anti-viral and other activities; animal models can also be used to study its pharmacokinetics in vivo and its effects on specific physiological and pathological processes. In this way, the true biological activity of this compound can be clarified, laying the foundation for subsequent drug development and other applications.