4as 7as 8 Cyano 1 Cyclopropyl 6 Fluoro 4 Oxo 7 Perhydropyrrolo 3 4 B 1 4 Oxazin 6 Yl 1 4 Dihydroquinoline 3 Carboxylic Acid Hydrochloride
Quinoline Thiophene Imidazole Thiazole
(-)-(4aS,7aS)-8-Cyano-1-cyclopropyl-6-fluoro-4-oxo-7-(perhydropyrrolo[3,4-b]-1,4-oxazin-6-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
Chemical Name (−)-(4aS,7aS)-8-Cyano-1-cyclopropyl-6-fluoro-4-oxo-7-(perhydropyrrolo[3,4-b]-1,4-oxazin-6-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
FAQ

What is the chemical structure of (-) - (4aS, 7aS) -8-cyano-1-cyclopropyl-6-fluoro-4-oxo-7- (perhydropyrrolido [3,4-b] -1,4-oxazine-6-yl) -1,4-dihydroquinoline-3-carboxylic acid hydrochloride?

It is not easy to understand the chemical structure of "3,4-dicarboxyl-1,4-dioxa-6-heptyl-1-cyclopropyl-8-amino-7-oxo-5-thio-1-azabicyclo [4.2.0] octyl-2-ene-2-carboxylic acid"! This is the category of organic chemistry, and its structure is complex, which requires professional knowledge and rigorous attitude.

Looking at this naming, according to the naming rules of organic chemistry, "biscyclic [4.2.0] octene-2-ene" shows that this compound has a bicyclic structure, the main ring is octene, and the double bond is located in the second position. "1,4-dioxane" means that the carbon atoms at positions 1 and 4 in the main ring are replaced by oxygen atoms. "5-thio" "1-azo" means that the 5th and 1st positions are occupied by sulfur atoms and nitrogen atoms, respectively. "8-amino" "7-oxo" "6-heptyl" "1-cyclopropyl" are all substituents, each in its corresponding position. " 3,4-Dicarboxyl "Table 3 and 4 are connected with carboxyl groups.

It is graphically depicted that the main ring is like a complex structure, and various heteroatoms and substituents are scattered on it like branches and leaves. Oxygen atoms change the electron cloud distribution and chemical activity of the main ring at positions 1 and 4; sulfur and nitrogen atoms also have their own characteristics, which affect the properties of compounds. Carboxyl groups are acidic, amino groups are basic, and both can participate in many chemical reactions. The tension of the cyclopropyl gene ring makes the molecular stability and reactivity different. The chain structure of heptyl groups adds flexibility and hydrophobicity to the molecule. < Br >
Although it is difficult to describe the details and delicacies, it is clear that this compound has a unique structure, and its properties and uses must be closely related to its complex structure. In the fields of organic synthesis, drug development, etc., it may have important value. It can be designed and synthesized with specific functions due to structural characteristics, which contributes to the development of science.

What are the main uses of (-) - (4aS, 7aS) -8-cyano-1-cyclopropyl-6-fluoro-4-oxo-7- (perhydropyrrolido [3,4-b] -1,4-oxazine-6-yl) -1,4-dihydroquinoline-3-carboxylic acid hydrochloride?

"Tiangong Kaiwu" has a saying: "Ash is sulfur and saltpeter are studied together, and it will be sent out in case of fire. Its smoke can smoke the eyes and is poisonous. However, it is widely used." Ash is now called the genus of chloric acid. The use of chloric anhydride is first in fireworks. The prosperity of fireworks is the most important for festivals. If it is burned, it will have a gorgeous light, shining people's eyes and extraordinary scenery, so it will increase the joy of festivals.

It is also used in military industry. The system of firearms, chloric anhydride is combined with various medicines, which can increase the power of medicine, and projectiles are sent to ward off the enemy, which is important for soldiers. In ancient wars, the benefits of firearms are related to victory and defeat, and the power of chloric anhydride must not be absent.

Furthermore, it is also useful in the chemical industry. It can be used as a medium for various reactions, assisting in the decomposition of chemical combinations, and turning into various useful things. Although its nature is strong, it can be used well, and it can benefit all kinds of industries.

And in the business of bleaching, chloric anhydride also has strengths. The color of the fabric, whether dark or miscellaneous, after it is bleached, it is as white as new, and the color is bright. It is indispensable in the textile industry.

The use of chloric anhydride adds the color of festivals to fireworks, the military industry guarantees the safety of the country, and the chemical industry promotes the prosperity of all industries. Bleaching enhances the beauty of fabrics. It is a useful thing in the world. Although it contains dangerous poisons, it is of great merit for people to use it well.

What is the preparation method of (-) - (4aS, 7aS) -8-cyano-1-cyclopropyl-6-fluoro-4-oxo-7- (perhydropyrrolido [3,4-b] -1,4-oxazine-6-yl) -1,4-dihydroquinoline-3-carboxylic acid hydrochloride?

To prepare benzyloxybenzoic anhydride, the method is as follows:

First take (-) - (4aS, 7aS) - 8-amino-1-cyclopropyl-6-fluoro-4-oxo-7 - ((permethoxyimino) [3,4-b]) - 1,4-diaza- 6 - group in a specific reaction vessel. This compound has a unique structure and each group is related to each other, which is the basis for subsequent reactions.

Then, appropriate reagents and conditions need to be introduced. From the concept of "Tiangong Kaiwu", just like the need to adjust the heat and ingredients for smelting, this reaction also needs to be precisely controlled. The appropriate acylating reagent can be selected, and the temperature, time and other factors of the reaction can be controlled. The choice of acylating reagent is related to the direction and yield of the reaction, just like the need to select good ore for metallurgy.

During the reaction, various atoms and groups in the molecule interact, such as the ancient art of war. Amino, cyclopropyl, fluoro and other groups either participate in the reaction, or affect the activity and selectivity of the reaction. At a suitable temperature, the reaction is gradually advanced, and the chemical bond breaking and formation are carried out in an orderly manner.

To complete the reaction, it still needs to be separated and purified. Just like gold panning needs to remove sediment, this process also needs to remove impurities such as unreacted raw materials and by-products. Benzyloxy benzoic anhydride can be purified by recrystallization, column chromatography and other methods to obtain high-quality products. In this way, the method for preparing benzyloxy benzoic anhydride is the method.

What are the pharmacological effects of (-) - (4aS, 7aS) -8-cyano-1-cyclopropyl-6-fluoro-4-oxo-7- (perhydropyrrolio [3,4-b] -1,4-oxazine-6-yl) -1,4-dihydroquinoline-3-carboxylic acid hydrochloride?

"Lei Gong Cannon Pharmaceutical Solution" contains: Borax, sweet and slightly salty in taste, cool in nature, non-toxic, mainly eliminates phlegm and stops coughing, breaks knots and laryngeal paralysis, removes the obstruction in the eyes, removes choking and diaphragm nausea, and is an important medicine for laryngeology. Its pharmacological effect is because it has the ability to clear away heat and reduce phlegm, detoxify and prevent corrosion. In the swollen throat, phlegm-hot cough and other diseases, borax can clear away heat and reduce fire, reduce phlegm and improve pharynx; in the blindness and obstruction of the eyes, it can clear away heat and clear the eyes, and subside the fungus membrane; in the disease of choking and diaphragm nausea, it can be used to reduce phlegm and eliminate accumulation, and reduce the stomach.

Borax has The lungs control the qi for breathing, and the phlegm heat accumulates in the lungs, and the cough is full of phlegm. Borax can clear the lung heat, reduce phlegm and relieve cough. The throat is the gateway to the lungs and stomach. Phlegm and fire attack, easy to cause sore throat, laryngeal paralysis, borax can detoxify and reduce swelling, dilute the pharynx and relieve pain. The eye is the eye of the liver, and the liver heat upwards disturbs the eye, causing blindness and blindness. Borax can clear the liver and relieve heat, and the eye fades. The stomach mainly accepts decomposed water and valleys. If the phlegm and qi are blocked, the stomach qi will go up, causing choking and nausea. Borax can reduce phlegm and qi, and reduce stomach inversion.

However, although borax has many effects, it needs to be used with caution. Because of its bor Medication should follow the doctor's advice and be treated according to the disease, constitution and other syndromes to achieve the best curative effect and ensure the safety of medication.

(-) - (4aS, 7aS) -8-cyano-1-cyclopropyl-6-fluoro-4-oxo-7- (perhydropyrrolido [3,4-b] -1,4-oxazine-6-yl) -1,4-dihydroquinoline-3-carboxylic acid What are the adverse reactions of hydrochloride

"Tiangong Kaiwu" says: "All things that are not contained in fire must be contained in water." Today, when it comes to carboxylic anhydride, there are some cases of intolerance to reactions. Let me tell you in detail.

Carboxylic anhydride is a kind of very important substance in organic compounds. On the stage of many chemical reactions, its performance varies. When it comes to intolerant reactions, the first one to bear the brunt is the situation of encountering water. Carboxylic anhydride meets water, just like fire meets rain, and is prone to hydrolysis. The change of hydrolysis is like a changing situation, and the structure of carboxylic anhydride quickly disintegrates under the action of water and converts into the corresponding carboxylic acid.

Furthermore, in an alkaline environment, carboxylic anhydride is also difficult to rest in its place. The alkali is like a powerful force that forcibly breaks the original tranquility of carboxylic anhydride, causing it to undergo reactions such as hydrolysis or alcoholysis. Once these reactions are started, they are like a runaway horse and cannot be easily contained.

In addition, some special carboxylic anhydrides, due to their unique structure, are also resistant to reactions under certain specific catalytic conditions. For example, when the activity of the catalyst is too high or the reaction temperature is not properly controlled, the carboxylic anhydride may undergo unexpected side reactions, deviating from the originally expected reaction path, just like a ship deviating from the established course.

All these indicate that carboxylic anhydride has the characteristics of intolerance to reaction under many reaction conditions. Just like everything in the world, it has its weaknesses and limitations. When using it, it is necessary to be careful and consider the reaction conditions and environment carefully in order to make carboxylic anhydride in the chemical reaction and exert its effective use to avoid the failure of the reaction due to intolerance or many unexpected situations.