What is the chemical structure of (4aR, 6aS, 7S) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11, 11a-tetradecahydro-1H-indeno [5,4-f] quinoline-7-carboxamide?

This is the name of an organic compound. In order to know its chemical structure, the name needs to be disassembled and analyzed according to the organic chemical nomenclature. " (4aR, 6aS, 7S) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetradecahydro-1H-indo [5,4-f] quinoline-7-formamide".

Wherein, " (4aR, 6aS, 7S) " is a chiral central configuration identification, which determines the stereochemical structure of molecular space. " N - [2,5-Bis (trifluoromethyl) phenyl] ", showing that the nitrogen atom is connected with a 2,5-bis (trifluoromethyl) phenyl group, and the 2,5 positions on this phenyl group are replaced by trifluoromethyl." 4a, 6a-dimethyl ", Table 4a, 6a have methyl groups." 2-oxo ", refers to the existence of 2 oxygen atoms in the molecule in the form of carbonyl groups." 2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetradecyl-1H-indeno [5,4-f] quinoline ", the core structure is indeno [5,4-f] quinoline, and multiple positions on this structure are hydrogenated and saturated." -7-formamide ", indicating the 7-position even formamide group.

In summary, the chemical structure of this compound contains a chiral center, the core is a specific hydrogenated indenoquinoline structure, the nitrogen atom is connected to a specific substituted phenyl group, the 7-position formamide group, the 4a, 6a-position methyl group, and the 2-position carbonyl group.

What are the main uses of (4aR, 6aS, 7S) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11, 11a-tetradecahydro-1H-indeno [5,4-f] quinoline-7-carboxamide?

(4aR, 6aS, 7S) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetradecyl-1H-indo [5,4-f] quinoline-7-formamide, which is widely used.

In the field of medicine, it is often used as an active ingredient to assist in the treatment of diseases. It may affect the pathological process of specific diseases, and regulate physiological functions by precisely combining with biological targets in the body, thereby exerting therapeutic effects. For example, in the development of anti-tumor drugs, such compounds may interfere with the growth, proliferation or metastasis mechanism of tumor cells, providing new strategies for combating cancer.

In the field of materials science, it also has potential applications. Due to the unique molecular structure, it may endow materials with novel physical and chemical properties. Or it can be used to prepare materials with special optical, electrical or thermal properties, such as in the field of organic optoelectronic materials, to help improve the photoelectric conversion efficiency of materials and promote the development of related technologies.

In the field of scientific research and exploration, as a research tool, it helps scientists to gain in-depth insight into biochemical and physiological processes. By studying its interaction with biomacromolecules, it can reveal the mystery of life activities, contribute to basic scientific research, and guide new research directions and breakthrough paths.

What are the synthesis methods of (4aR, 6aS, 7S) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11, 11a-tetradecahydro-1H-indeno [5,4-f] quinoline-7-carboxamide?

The synthesis method of (4aR, 6aS, 7S) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydro-1H-indo [5,4-f] quinoline-7-formamide is due to the organic synthesis method, which is complex and diverse, and each has its own subtlety.

First, fluorophenyl can be introduced by the method of nuclear substitution from the corresponding nitrogen-containing heterocyclic compound. In a suitable solvent, such as dichloromethane, N, N-dimethylformamide, with alkalis such as potassium carbonate and triethylamine to help the reactants interact. This step requires temperature control and reaction time to prevent side reactions from breeding.

Furthermore, when constructing a fused ring structure, a cyclization reaction may be used. Use a suitable catalyst, such as Lewis acid, to catalyze the formation of intramolecular rings. Under the protection of an inert gas, such as a nitrogen environment, the reaction temperature and catalyst dosage can be precisely adjusted to obtain the target fused ring structure.

The reaction conditions can be optimized by modifying the substituents to improve the purity and yield of the product. For example, finely adjusting the proportion of reactants and selecting more suitable solvents and additives can be the key to synthesis. However, the synthesis method requires repeated experiments and fine-tuning strategies according to actual results to achieve the ideal synthesis effect and obtain this complex organic compound.

(4aR, 6aS, 7S) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11, 11a-tetradecahydro-1H-indeno [5,4-f] What are the physicochemical properties of quinoline-7-carboxamide?

(4aR, 6aS, 7S) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydro-1H-indo [5,4-f] quinoline-7-formamide This substance has the following physicochemical properties.

Its appearance is often white to off-white solid, stable at room temperature and pressure. From the melting point point, about [X] ℃, this property is essential for identification and purity determination. In terms of solubility, it is slightly soluble in water, but soluble in common organic solvents, such as dichloromethane, N, N-dimethylformamide, etc. It has good solubility in dichloromethane, due to the lipophilic groups in the molecular structure, such as 2,5-bis (trifluoromethyl) phenyl group and long carbon chain part, which makes the van der Waals force between the molecule and the organic solvent stronger.

In terms of chemical stability, due to the amide bond, hydrolysis will occur in the case of strong acid or strong base, and the amide bond will be broken to generate corresponding amine and carboxylic acid derivatives. And the aromatic ring structure in the molecule can undergo electrophilic substitution reactions under specific conditions, such as halogenation, nitrification, etc. Because the electron cloud density distribution on the aromatic ring is affected by the substituent group, its reactivity is different. The multiple chiral centers in the molecule endow it with optical rotation, and the enantiomers may have significant differences in biological activity and pharmacological properties.

The physicochemical properties of this compound are closely related to its structure, laying an important foundation for its application in the fields of synthesis, separation and biological activity research.

What is the market outlook for (4aR, 6aS, 7S) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11, 11a-tetradecahydro-1H-indeno [5,4-f] quinoline-7-carboxamide?

There is now a product named (4aR, 6aS, 7S) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydro-1H-indo [5,4-f] quinoline-7-formamide. The market prospect of this product is related to many aspects, and listen to me in detail.

Looking at the current field of medicine, we are very eager to explore new compounds. This compound has a unique structure or special biological activity. If it emerges in pharmacological research, it may become the cornerstone of new drugs. In today's pharmaceutical market, there are many unmet needs for various diseases. If this compound can be effective for difficult diseases, it will definitely attract the attention of pharmaceutical companies, and then invest in research and development, and its market prospects will be promising.

Furthermore, the chemical industry is also promising. Because it contains special groups, such as trifluoromethyl, such groups endow compounds with unique physical and chemical properties, and may have potential uses in materials science and other fields. If it can be prepared on a large scale after the chemical production process is optimized, and the cost is controllable, it will be able to open up new markets and occupy a place in the chemical industry.

However, there are challenges ahead in the market. The research and development of new drugs takes a long time and requires huge investment. From basic research to clinical trials, to approval for marketing, there are many obstacles. In terms of chemical applications, the exploration of large-scale preparation processes needs to overcome many technical problems, and environmental protection requirements are becoming increasingly stringent, and the production process must comply with the concept of green chemistry.

Overall, (4aR, 6aS, 7S) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydro-1H-indeno [5,4-f] quinoline-7-formamide If it can break through the technical and research and development difficulties, it is expected to shine in the pharmaceutical and chemical markets, and the prospects are promising; if it is difficult to break through, the market development may be blocked.