What is the chemical structure of (4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-tert-butyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5, 6, 6a, 7, 8, 9, 9a, 9b, 10, 11, 11a-tetrahydro-1H-indo [5, 4-f] quinoline-7-formamide?

The chemical structure of (4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-benzyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydro-1H-naphthaleno [5,4-f] pyran-7-acetic acid is an interesting topic in the field of organic chemistry.

Looking at the naming of this compound, it follows the naming rules of organic chemistry and contains rich structural information. " (4aR, 4bS, 6aS, 7S, 9aS, 9bS) " represents the configuration of the chiral center, which is the key element that determines the stereochemical properties of the compound. Chirality is similar to human right and left hands, although similar but cannot overlap, and has a significant impact on the physical, chemical and biological activities of compounds.

"N-benzyl" indicates that the nitrogen atom is connected to the benzyl group, and the benzyl group is benzyl, which endows the molecule with specific chemical and spatial characteristics. "4a, 6a-dimethyl" indicates that there are methyl substituents at the positions 4a and 6a, and the introduction of methyl groups alters the electron cloud distribution and spatial hindrance of the molecule.

"2-oxo" reveals the existence of carbonyl groups at the No. 2 position in the molecule. Carbonyl groups have strong polarity, which has a profound impact on the reactivity and chemical properties of the molecule. It is often the activity check point of chemical reactions.

"2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetradecahydro" shows that the compound is formed from the naphthaleno [5,4-f] pyran parent nucleus through fourteen hydrogenations, and the hydrogenation process changes the degree of unsaturation and stability of the molecule.

"1H-naphthaleno [5,4-f] pyran" defines the parent nuclear structure. The naphthaleno-pyran structure fuses the naphthalene ring with the pyran ring, giving the molecule a unique conjugation system and optical properties.

"-7-acetic acid" indicates that the acetate group is connected at position 7, and this acidic group gives the compound specific acid-base properties and reactivity.

To sum up, the chemical structure of (4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-benzyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetradecyl-1H-naphthalene and [5,4-f] pyran-7-acetic acid is an exquisite combination of various groups and specific configurations, and the interaction of each part jointly determines the unique properties and reactivity of the compound.

(4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-tert-butyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5, 6, 6a, 7, 8, 9, 9a, 9b, 10, 11, 11a-tetradecyl-1H-indo [5, 4-f] quinoline-7-formamide What are the physical properties?

(4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-benzyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a + -tetradecyl-1H-naphthaleno [5,4-f] pyran-7-acetic acid is a complex organic compound. As for its physical properties, this compound may be crystalline in appearance and optically active because it contains multiple chiral centers. Due to its complex structure, its melting point and boiling point are difficult to accurately infer by general laws. In terms of polarity, due to the presence of polar groups such as carbonyl groups, it has a certain polarity and may have good solubility in organic solvents, such as common organic solvents ethanol, acetone, etc. However, its solubility in water may not be good because of its non-strong hydrophilic structure. In addition, the compound contains multiple cyclic structures, resulting in strong molecular rigidity, which also affects its physical properties. For example, in the crystalline state, intermolecular forces or the arrangement of cyclic structures exhibit specific rules.

This compound contains a variety of functional groups, and carbonyl groups have certain reactivity, which can participate in reactions such as nucleophilic addition. Its cyclic structure stability may affect the reactivity and selectivity. These structural characteristics determine that the compound may have potential applications in organic synthesis, medicinal chemistry, and other fields. Studying its physical properties is crucial to understanding its behavior and applications.

What are the chemical properties of (4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-tert-butyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5, 6, 6a, 7, 8, 9, 9a, 9b, 10, 11, 11a-tetrahydro-1H-indono [5, 4-f] quinoline-7-formamide?

(4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-benzyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a + tetrahydro-1H-naphthaleno [5,4-f] furan-7-acetic acid What are the chemical properties of this compound? This is a question about the characteristics of organic compounds. I should use the ancient saying to solve your doubts.

This compound has a complex structure and contains many chiral centers. Its three-dimensional configuration has a great influence on its chemical properties. With its N-benzyl group, the benzyl group part has certain stability, and the benzene ring can participate in electron conjugation. The substitution of dimethyl groups has its role in the molecular spatial arrangement, or affects the intermolecular forces and reaction check points.

Furthermore, the 2-oxo structure, that is, the carbonyl group, is an active functional group and can undergo many reactions. Carbonyl groups are electrophilic and vulnerable to attack by nucleophiles. For example, they can condensate with alcohols to form esters or amines to form imines. At the same time, the α-hydrogen of carbonyl groups has a certain acidity, which can be taken away under the action of appropriate bases, and then initiate subsequent reactions.

The structure of tetrahydronaphthalenofuran also has its own characteristics. The naphthalenofuran skeleton provides a certain rigidity and conjugation system, which affects the electron cloud distribution of molecules. The chemical environment of the surrounding hydrogen atoms is different, and it can present unique signals in analysis such as nuclear magnetic resonance.

As for the side chain of acetic acid, the -COOH functional group is acidic and can react with bases to form salts or esterification reactions with alcohols. In summary, this compound exhibits various chemical properties due to the interaction of various parts, and may have unique uses in organic synthesis and other fields.

(4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-tert-butyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5, 6, 6a, 7, 8, 9, 9a, 9b, 10, 11, 11a-tetradecyl-1H-indono [5, 4-f] quinoline-7-formamide In what areas are applications?

(4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-benzyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a + -tetradecyl-1H-naphthaleno [5,4-f] furan-7-acetic acid has applications in many fields.

In the field of pharmaceutical research and development, the unique chemical structure of this compound gives it potential biological activity. For example, due to the specific atomic arrangement and connection mode in its structure, it can interact with specific biological targets in the human body. Some functional groups it contains, such as dimethyl and oxo groups, can participate in the binding process of biological macromolecules, such as binding to proteins, enzymes and other targets, regulating related physiological processes in organisms, and then may be developed for the treatment of specific diseases, such as inflammation-related diseases or neurological diseases, because it may affect the release of inflammatory mediators or neurotransmitter regulation.

In the field of organic synthesis, it can be used as a key intermediate. Due to its structural complexity and diversity, it can be modified by specific chemical reactions. For example, by using the activity check points it contains, substitution reactions, addition reactions, etc., to construct more complex organic molecular structures. Based on it, derivatives with different functions can be further synthesized for use in materials science, total synthesis of natural products and other fields.

In the field of materials science, based on the structural properties of this compound, if it is introduced into polymer materials, it may endow the material with unique properties. For example, its rigid naphthalene-furan structure part can increase the mechanical strength of the material, while the flexible acetic acid side chain part can adjust the solubility and processability of the material, making it show application potential in the research and development of new polymer materials.

What is the synthesis method of (4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-tert-butyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5, 6, 6a, 7, 8, 9, 9a, 9b, 10, 11, 11a-tetrahydro-1H-indono [5, 4-f] quinoline-7-formamide?

To prepare (4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-benzyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydronaphthalene and [5,4-f] furan-7-formic acid, the method is as follows:

Take an appropriate amount of starting materials first, and combine them through clever reaction steps. Benzyl can be introduced in a specific reaction first. This process requires attention to the precise control of reaction conditions, such as temperature and catalyst dosage. Too high or too low temperature may affect the efficiency and positional selectivity of benzyl introduction.

Then, proceed to the introduction step of dimethyl. This step also requires fine operation, selecting suitable reagents and reaction environment to ensure that dimethyl can be precisely connected to the positions of 4a and 6a.

Then carry out the oxygen substitution reaction, which is the key to building the 2-oxygen substitution structure. Appropriate oxidants need to be selected to control the reaction process and avoid excessive oxidation or insufficient oxidation.

In the subsequent multi-step reaction, after a series of complex cyclization, hydrogenation and other reactions, the structure of tetrahydronaphthalene [5,4-f] furan is gradually constructed. The intermediate needs to be properly handled between each step to ensure its purity and stability, so as not to affect the progress of subsequent reactions.

Each step of the reaction requires timely adjustment of reaction parameters, such as reaction time, solvent type, etc. After many fine operations and clever regulation, (4aR, 4bS, 6aS, 7S, 9aS, 9bS) -N-benzyl-4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydronaphthalene [5,4-f] furan-7-carboxylic acid can be successfully prepared.