4ar 4bs 6as 7s 9as 9bs 11ar N 2 5 Bis Trifluoromethyl Phenyl 4a 6a Dimethyl 2 Oxo 2 4a 4b 5 6 6a 7 8 9 9a 9b 10 11 11a Tetradecahydro 1h Indeno 5 4 F Quinoline 7 Carboxamide
Quinoline Thiophene Imidazole Thiazole
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-bis(trifluoromethyl)phenyl]-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
Chemical Formula C32H30F6N2O2
Molecular Weight 604.58
Iupac Name (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-bis(trifluoromethyl)phenyl]-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
FAQ

(4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11, 11a-tetradecahydro-1H-indeno [5,4-f] What is the chemical structure of quinoline-7-carboxamide

This is the chemical name of (4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydro-1H-indano [5,4-f] quinoline-7-formamide. To understand its chemical structure, it should be described in the ancient style of "Tiangong Kaiwu".

Looking at this name, it can be seen that this compound has a complex structure. Its core is composed of a fused polycyclic system, which is like a pavilion carefully built by ancient craftsmen. The framework of indeno [5,4-f] quinoline is like the main body of a pavilion, solid and stable. On the skeleton, dimethyl is added at positions 4a and 6a, which is like the decoration of the two corners of the pavilion, giving it a unique spatial configuration.

Looking at its side chain, the N atom is connected to [2,5-bis (trifluoromethyl) phenyl], which is like the eaves protruding from the pavilion, adding complexity and uniqueness to the overall structure. The formamide group at position 7, like the exquisite wind chimes hanging under the pavilion, has a great impact on the properties and activities of the compound.

The part of the 2-oxygen generation, if one of the pavilions is exquisitely carved, changes the distribution of the electron cloud, which in turn affects the chemical properties of the whole. The modification of tetrahydrogens greatly increased the saturation of the entire skeleton, such as adding layers of bricks to a pavilion, changing its stability and reactivity. The chemical structure of this compound is like a masterpiece carefully crafted by ancient skilled craftsmen. The parts are closely connected and interact with each other to form a unique and complex chemical entity.

(4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11, 11a-tetradecahydro-1H-indeno [5,4-f] What are the physical properties of quinoline-7-carboxamide

This compound is named (4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydro-1H-indo [5,4-f] quinoline-7-formamide. The following describes its physical properties in the style of ancient Chinese:

This compound has unique physical properties. Under normal conditions, it may be in a crystalline state, and its crystal structure is regular and orderly, similar to the exquisite structure of nature. Looking at its color, it may be colorless to slightly yellow, with a pure and delicate texture and a warm luster, like the quality of ancient jade.

Melting point is the key to measure its physical properties. When heated, it reaches a specific temperature and begins to melt into a liquid state. This melting point temperature is an inherent characteristic of the substance, which can be accurately measured and is an important basis for identification and identification.

In terms of solubility, it may have good solubility in specific organic solvents. Organic solvents such as alcohols and ethers are mixed with them and can be miscible to form a uniform solution, just like water emulsion. In water, it may have poor solubility, just like oil and water, and it is difficult to blend. This property is also closely related to the molecular structure.

Its density is also one of the characteristics, and it has its unique value compared with common substances. Although it is difficult to distinguish the density difference with the naked eye, it can be measured with precise instruments, and its value reflects the compactness of the particles inside the material, just like a measure of the internal density of the material.

In addition, the volatility of the compound is very small, and it is difficult to evaporate in the air at room temperature and pressure. It is like a stable thing and does not easily disperse. This property makes it highly stable and easy to store and use.

(4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11, 11a-tetradecahydro-1H-indeno [5,4-f] What is the main use of quinoline-7-carboxamide

This is a chemical substance named (4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydro-1H-indo [5,4-f] quinoline-7-formamide. Its use often involves research and development in the field of medicine.

In the way of modern medicine exploration, these compounds are like secret treasures. Their unique chemical structure may be precisely matched with specific biological targets, just like a delicate key matched with a special lock. Or it can adjust the biochemical reactions in the organism and play a therapeutic effect on specific diseases, such as some stubborn tumor diseases, or intractable neurological diseases.

It may also be used in scientific research experiments, as a powerful tool for exploring the mysteries of life. It helps researchers to understand the fine working mechanism of the living body, just like lighting a light for exploring the labyrinth of life, helping them to clarify the mysteries of various biomolecular interactions, so as to gain more precious knowledge about the essence of life.

(4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11, 11a-tetradecahydro-1H-indeno [5,4-f] What are the synthesis methods of quinoline-7-carboxamide

(4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetradecyl-1H-indeno [5,4-f] quinoline-7-formamide The ancient saying is as follows:

To make this substance, the path of organic synthesis is often followed. The choice of starting materials is about success or failure. Or take aromatic hydrocarbons with specific substituents, such as benzene derivatives containing trifluoromethyl groups, as the basis for constructing the phenyl moiety. Its combination with heterocyclic compounds containing appropriate activity check points, such as quinoline derivatives with alkenyl or halogenated groups, can be a key step.

Reaction conditions are also essential. The choice of catalytic system, or the use of transition metal catalysts, such as palladium, rhodium, etc. complexes, to promote arylation, cyclization and other reactions. The control of temperature and solvent should not be underestimated. Under moderate temperature, or in organic solvents, such as toluene, dichloromethane, etc., the reaction proceeds in an orderly manner.

The cyclization step can be used for intra-molecular ring reactions. Under suitable reagents and conditions, the intramolecular groups interact to construct the fused ring structure of indenoquinoline. Among them, the transformation, protection and deprotection strategies of functional groups need to be carefully designed. For example, hydroxyl, amino and other groups, add protective groups before the reaction to prevent their improper reaction, and then deprotect at an appropriate time to obtain the target structure.

After several steps of reaction, the product is separated and purified in each step, and column chromatography and recrystallization are commonly used. After many setbacks, we finally obtained (4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydrogen- 1H-indeno [5,4-f] quinoline-7-formamide. This synthesis path requires fine operation and clever planning to achieve the expected effect.

(4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11, 11a-tetradecahydro-1H-indeno [5,4-f] quinoline-7-carboxamide

Today there are (4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydro-1H-indeno [5,4-f] quinoline-7-formamide, and its market prospects are related to many aspects.

Looking at this compound, from the perspective of the pharmaceutical field, it may have unique pharmacological activities. Nowadays, the pharmaceutical market has a strong demand for new specific drugs. If this compound is studied in depth and proved to have significant efficacy in the treatment of specific diseases such as tumors and nervous system diseases, it will surely attract the attention of pharmaceutical companies, and the market prospects are limitless. However, the road to pharmaceutical research and development is bumpy, requiring rigorous clinical trials, and many links test the possibility of its drug.

In the chemical industry, if its synthesis process can be optimized, large-scale production can be achieved and the cost is controllable, it may become a new type of chemical material intermediate. Today's chemical industry pursues innovation and green sustainability. If this compound can meet the relevant requirements, it may be able to emerge in the research and development of new materials and expand into new market areas.

However, its market prospects are also facing challenges. Similar competitors may have occupied part of the market share, and to stand out, they need to demonstrate unique advantages. And environmental regulations are increasingly stringent, and the production process must meet green standards, otherwise it will be restricted.

In summary, (4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 5,6,6a, 7,8,9,9a, 9b, 10,11,11a-tetrahydro-1H-indo [5,4-f] quinoline-7-formamide market prospects, although there are opportunities, but also need to overcome many difficulties in order to gain a place in the market.