4 Trifluoromethyl Quinoline 3 Carboxylic Acid
quinoline thiophene imidazole thiazole

4-(Trifluoromethyl)Quinoline-3-Carboxylic Acid

Taiy Chemical

    Specifications

    HS Code

    503090

    Chemical Formula C11H6F3NO2
    Molecular Weight 241.17
    Appearance Solid (usually white to off - white powder)
    Melting Point Data - specific to determination method, typically in a certain range
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Pka Value Characteristic acidic dissociation constant, specific value for carboxyl group
    Density Data - needs experimental determination
    Stability Stable under normal storage conditions away from strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 4-(Trifluoromethyl)Quinoline-3-Carboxylic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 4- (trifluoromethyl) quinoline-3-carboxylic acid?
    What is the main user of (triethylphenyl) square acid-3-carboxylate? This is a chemical field with a wide range of applications.
    In the field of organic synthesis, it is a key intermediate. With its unique structure, it can react with various chemical reactions and various reagents to construct various complex organic molecules. For example, it can be used by esterification reaction to combine with alcohols to obtain esters with special properties. This ester may be used in flavors, pharmaceutical synthesis, etc. It can also be amidated and combined with amines to form amide products, which are used in the preparation of polymer materials or as important monomers to improve the properties of materials. < Br >
    In the field of materials science, (triethylphenyl) square acid-3-carboxylate also has extraordinary performance. Due to the characteristics of its molecular structure, it can be used to prepare photoelectric materials. It may exhibit excellent photoelectric conversion performance under specific conditions, so it is expected to be used in solar cells and other devices to improve the conversion efficiency of light energy to electricity. And because of its structural stability, it may enhance the durability and stability of materials and prolong the service life of devices.
    In the field of biomedicine, it also has its potential use. After reasonable structural modification and modification, it may have certain biological activity. For example, it can be used as a drug carrier to wrap drug molecules with its special structure, achieve targeted delivery of drugs, improve the efficacy of drugs, and reduce the side effects on normal tissues. Or it has certain pharmacological activity and can be directly used in the treatment of diseases, but it still needs in-depth research and verification.
    From this point of view, (triethylphenyl) square acid-3-carboxylate has important uses and broad application prospects in many fields such as organic synthesis, materials science, and biomedicine.
    What are the physical properties of 4- (trifluoromethyl) quinoline-3-carboxylic acid?
    Trivinylboronic acid-3-carboxylate is a unique compound with numerous physical properties and important applications in many fields.
    Looking at its appearance, it is often in the form of white to off-white crystalline powder, which is easy to store and use. In laboratory operations and industrial production processes, this form is easy to accurately weigh and mix, providing convenience for subsequent reactions.
    When it comes to solubility, the compound can exhibit a certain solubility in some organic solvents such as ethanol and acetone. This property makes it possible to conveniently select suitable solvents according to reaction requirements in the field of organic synthesis, so as to better participate in various chemical reactions. In the dispersion system of a specific organic solvent, trivinylboronic acid-3-carboxylate can be fully contacted with other reactants to promote the smooth progress of the reaction.
    At the stability level, under normal temperature and pressure and dry environment, trivinylboronic acid-3-carboxylate has good stability and can be stored for a long time without significant deterioration. However, it should be noted that this compound is quite sensitive to humidity and is prone to hydrolysis in contact with water, resulting in structural changes that affect its chemical properties and application effects. Therefore, be sure to keep the environment dry when storing to avoid contact with water vapor.
    In terms of melting point, trivinylboronic acid-3-carboxylate has a specific melting point value, which is of great significance for its purity identification and behavior research under high temperature reaction conditions. By accurately measuring the melting point, the purity of the compound can be judged, providing a key basis for quality control. In high temperature reaction environments, melting point parameters help to evaluate its physical state transition at different temperature stages, thereby optimizing reaction conditions, improving reaction efficiency and product quality.
    Is the chemical property of 4- (trifluoromethyl) quinoline-3-carboxylic acid stable?
    The chemical properties of (triethylphenyl) boric acid and phthalic acid are quite stable.
    (triethylphenyl) boric acid, the boron atom in its molecular structure is connected to three ethylphenyl groups, which endows it with certain stability. Under common chemical reaction conditions, it can maintain its own structure without the action of specific extreme reagents such as strong oxidants, strong acids or strong bases. For example, it will not spontaneously decompose at room temperature and pressure without special catalysts. At the same time, the electronic effect and steric resistance effect of ethylphenyl also contribute to its stability. The electron-giving effect of ethylphenyl increases the electron cloud density around boron atoms, which enhances the bonding stability between boron atoms and other atoms to a certain extent. < Br >
    Phthalic acid, with the structure of a benzene ring and two carboxyl groups. The benzene ring itself has high stability, and its large π bond system makes the electron cloud distribution more uniform, which is not easy to be destroyed by general reagents. Although the carboxyl group has a certain activity, it can remain relatively stable under normal circumstances as long as there are no substances that can strongly react with the carboxyl group, such as strong reducing agents, specific dehydrating agents, etc. Like in general storage environments, when there are no extreme changes in temperature and humidity, phthalic acid will not easily deteriorate. Even in some common organic solutions, if these solutions do not have active groups that chemically react with phthalic acid, it can maintain its own chemical stability.
    What are the synthesis methods of 4- (trifluoromethyl) quinoline-3-carboxylic acid?
    To prepare 4 - (triethylamino) benzoic acid - 3 - aldehyde, the method is as follows:
    First, start with 3 - aldehyde benzoic acid, first react with halogenated acetonitrile under alkali catalysis to form the corresponding cyano derivative, then treated with triethylamine, nucleophilic substitution, cyano to triethylamino, and finally with a suitable reducing agent, such as lithium aluminum hydride, cyano is reduced to aldehyde group to obtain the product. This step is slightly complicated, but the reaction conditions of each step are easier to control, and the yield is considerable.
    Second, starting from 3-nitrobenzoic acid, first reduce the nitro group to an amino group, then react with halogenated acetonitrile to introduce a cyano group, and then replace it with triethylamine to obtain a compound containing triethylamino group and nitro group, and then selectively reduce the nitro group to an aldehyde group, which can become the target. The reduction of the nitro group to an amino group and the subsequent reduction of the nitro group to an aldehyde group requires the selection of suitable reagents and conditions to achieve high selectivity.
    Third, use isophenyldiformaldehyde as the raw material, its first aldehyde group is protected, and the rest reacts with amino-containing reagents to introduce triethylamino group, and then deprotect the aldehyde group to obtain the product. The key to this path lies in the step of aldehyde protection and deprotection, and the proper protection group and conditions are selected to ensure the smooth reaction and good yield.
    All synthetic methods have their own advantages and disadvantages. In actual operation, it is necessary to comprehensively weigh and weigh various factors such as raw material availability, reaction conditions, cost and yield, and choose the optimal path to efficiently obtain 4- (triethylamino) benzoic acid-3-aldehyde.
    What is the price range of 4- (trifluoromethyl) quinoline-3-carboxylic acid in the market?
    Today there are four things, called (trienyl methyl) square light, (3-carboxyl), what is the price in the market? This question is related to business affairs, but it is not easy to know its price.
    Looking at the market, prices are changeable, and they change with changes in supply and demand and changing times. The price of (trienyl methyl) square light and (3-carboxyl) things also follows this law. Or there is a price difference due to differences in origin and quality.
    I have heard of Zhujia people, such things have a wide range of prices. (trienyl methyl) square light, or due to the difficulty of making or using it, the price is often high. If the quality is good and pure, each can be worth a lot of gold; if the quality is poor, the price will also drop. The price may range from tens of gold to hundreds of gold, depending on the market conditions.
    As for (3-carboxyl), its price also varies according to the use and output. If the supply exceeds the demand, the price will be low; if there are many people who need it, and those who produce it are rare, the price will be high. Roughly speaking, its price may be between a few gold and a few tens of gold.
    However, the market is unstable, and the price is not fixed. If you want to know the real-time price, you must visit the market in person, consult the merchants, and observe the status of supply and demand. Only when the situation changes can you get a definite number. Pricing must not be based on assumptions, but must be based on actual observations.