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What is the chemical structure of 4-Quinolinepropanoic acid, α-amino-1,2-dihydro-2-oxo-, hydrochloride (1:1)
This is called 4-quinoline propionic acid, α-amino-1,2-dihydro-2-oxo-hydrochloride (1:1). To clarify its chemical structure, it is necessary to analyze it from the nomenclature.
"4-quinoline propionic acid" shows that its parent nucleus is quinoline, with a propionic acid group attached to the fourth position of the quinoline ring. Quinoline, with the structure of azanaphthalene, is formed by fusing a benzene ring with a pyridine ring. The propionic acid group is a carboxyl side chain composed of three carbon atoms, which is connected to a specific position of the quinoline ring.
"α-amino-1,2-dihydro-2-oxo-" indicates that an amino group is introduced at the α position of the propionic acid group (the carbon atom connected to the carboxyl group), and the 1,2 positions of the quinoline ring undergo a dihydrogen process, while the 2-position aerobic atom forms a carbonyl group. These modifications make the chemical properties and activities of the molecule unique.
"Hydrochloride (1:1) " means that the compound forms a salt with hydrochloric acid, and the ratio of the compound to hydrochloric acid is 1:1. This salt formation process may change the solubility, stability and other physical and chemical properties of the compound.
In summary, the chemical structure of 4-quinoline propionic acid, α-amino-1,2-dihydro-2-oxo-hydrochloride (1:1) is the quinoline ring with 4-position propionic acid group, α-position has amino group, 1,2-position has specific modification, and the unique structure of salt with hydrochloric acid.
What are the physical properties of 4-Quinolinepropanoic acid, α-amino-1,2-dihydro-2-oxo-, hydrochloride (1:1)
4-Quinoline propionic acid, α-amino-1,2-dihydro-2-oxo-hydrochloride (1:1), this is an organic compound. Its physical properties are crucial and are related to many practical applications.
Looking at its morphology, it is often in the state of white to off-white crystalline powder. This morphology makes it relatively convenient for storage and transportation. Because of its good stability, it is not easy to affect its properties due to morphological changes.
In terms of solubility, the compound exhibits a certain solubility in water and can be moderately dissolved. This property is of great significance in the field of drug preparation, because many drugs need to play a role in the solution environment. And it also has a certain solubility in some organic solvents, such as ethanol, which provides more possibilities for its application in different chemical processes.
Melting point is also one of its important physical properties. After measurement, the melting point is within a specific range. This melting point determines the physical state transition temperature during the heating process. In the purification and identification of compounds, the melting point is often the key judgment basis.
Furthermore, its density also has a corresponding value. This value is crucial for calculating the relationship between mass and volume in processes involving accurate measurement such as chemical production, ensuring the accuracy and stability of the production process.
In addition, the compound has weak hygroscopicity, and under conventional ambient humidity, it is not easy to absorb a large amount of water and cause deliquescence, which further enhances its storage stability. All these physical properties together constitute the unique physical properties of this compound, which lays the foundation for its application in medicine, chemical industry and other fields.
What is the use of 4-Quinolinepropanoic acid, α-amino-1,2-dihydro-2-oxo-, hydrochloride (1:1)
4-Quinoline propionic acid, α-amino-1,2-dihydro-2-oxy-, hydrochloride (1:1), this substance is used in various pharmaceutical and chemical fields.
In the field of medicine, it may be a key pharmaceutical intermediate. In the field of pharmaceutical chemistry, such compounds are often used as cornerstones to build complex drug molecular structures through delicate reactions. Because of its unique structure, it may endow the final product with specific pharmacological activities, helping it target specific targets in the body, such as targets involved in neurotransmitter regulation, or targets related to cell proliferation and apoptosis. This may be used to develop anti-depressant, anti-epileptic and other neurological drugs, or anti-tumor drugs. Due to the complex mechanism of abnormal proliferation of tumor cells, this compound may be able to interfere with the key metabolic pathways of tumor cells and inhibit their growth and diffusion by virtue of its structural properties.
In the chemical field, it can be used to create materials with special functions. The method of organic synthetic chemistry can integrate it into the skeleton of polymer materials. Because of its own chemical activity, it may improve the stability, hydrophilicity or biocompatibility of the material. For example, in biodegradable materials used in biomedical engineering, adding this substance may regulate the degradation rate of the material, making it compatible with the tissue repair process, and can also enhance the interaction between the material and the cell, promote cell adhesion and proliferation, and facilitate tissue regeneration. Furthermore, in fine chemical products, such as high-end coatings and inks, it can be used as a functional additive to improve product rheology, weather resistance, and other properties, and enhance product quality.
What is the synthesis method of 4-Quinolinepropanoic acid, α-amino-1,2-dihydro-2-oxo-, hydrochloride (1:1)
Now there are 4 - Quinolinepropanoic acid, α - amino - 1, 2 - dihydro - 2 - oxo -, hydrochloride (1:1), to be prepared, the method is as follows.
First take an appropriate amount of 4 - quinolinepropanoic acid derivative, this derivative needs to have a modifiable α position. In a suitable reaction vessel, prepare a suitable organic solvent, such as dichloromethane, N, N - dimethylformamide, etc., depending on the reaction requirements and substrate characteristics. < Br >
The reaction system is cooled to an appropriate low temperature, such as between 0 ° C and -20 ° C, and amination reagents, such as suitable solutions of ammonia gas, amine compounds, etc., are slowly added to make the amination reaction occur at the α position. During the reaction process, the reaction process needs to be closely monitored, and thin layer chromatography (TLC) or other suitable analytical methods can be used. When the amination reaction reaches the desired level, it should be heated to room temperature or moderately heated to make the reaction more complete.
Then, the resulting product is separated and purified. Column chromatography can be used. Silica gel is used as the fixed phase, and a suitable eluent, such as a mixed solvent of petroleum ether and ethyl acetate, can be used to separate the target product according to the polarity difference of the product. < Br >
Then place the purified product in another reaction vessel, add an appropriate amount of hydrogen chloride gas or a suitable solution, such as ethanol hydrochloride solution, under normal temperature or moderate heating conditions, to form a salt, to obtain 4 - Quinolinepropanoic acid, α - amino - 1,2 - dihydro - 2 - oxo -, hydrochloride (1:1). Finally, after crystallization, filtration, drying and other steps, the pure target product can be obtained.
What is the safety of 4-Quinolinepropanoic acid, α-amino-1,2-dihydro-2-oxo-, hydrochloride (1:1)
4 - Quinolinepropanoic acid, α - amino - 1, 2 - dihydro - 2 - oxo -, hydrochloride (1:1), is a chemical substance. The safety of this substance is related to many aspects.
In terms of toxicity, although there is no detailed ancient Chinese classic book to compare. However, according to today's chemical analysis, it may have certain toxicity. When exposed to the human body, if ingested orally, it may cause gastrointestinal discomfort, such as nausea, vomiting, abdominal pain, etc., due to irritation and damage to the gastrointestinal mucosa. If it is exposed to the skin, or triggers an allergic reaction, erythema or itching may appear, due to its chemical structure or binding to skin proteins, causing the immune system to misjudge.
In terms of environmental impact, its degradation in the natural environment is complex. If it flows into the water body, it may affect the survival of aquatic organisms. Microbial communities in the water may be disturbed, causing ecological imbalance. And this substance remains in the soil, or affects plant growth, root development or hindrance, and plants may be stunted.
In terms of operation safety, although the ancients did not mention it, today's operating practices are very important. When operating, it needs to be in a well-ventilated place, due to volatile aerosols or harmful. Operators wear protective clothing, goggles and gloves to prevent contact injuries. Storage should also be cautious, should be placed in a cool, dry place, away from fire and oxidants, due to its chemical properties or make it unstable under improper conditions, resulting in danger. In general, the safety of this substance needs to be treated with caution, in accordance with today's scientific understanding and standard operation to reduce harm.