4 Quinolinepropanoic Acid A 4 Chlorobenzoyl Amino 1 2 Dihydro 2 Oxo R
quinoline thiophene imidazole thiazole

4-Quinolinepropanoic acid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-, (R)-

Taiy Chemical

    Specifications

    HS Code

    786865

    Chemical Formula C20H15ClN2O4
    Molecular Weight 382.799 g/mol
    Iupac Name (R)-α-[(4 - Chlorobenzoyl)amino]-1,2 - dihydro - 2 - oxo - 4 - quinolinepropanoic acid
    Physical State Solid (predicted)
    Melting Point No data found
    Boiling Point No data found
    Solubility Soluble in organic solvents (predicted)
    Density No data found
    Appearance No data found
    Pka No data found
    Logp No data found

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    General Information
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    Frequently Asked Questions

    As a leading 4-Quinolinepropanoic acid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-, (R)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 4-Quinolinepropanoic acid, a- [ (4-chlorobenzoyl) amino] -1,2-dihydro-2-oxo-, (R) -
    (R) -alpha - [ (4-chlorobenzoyl) amino] -1,2-dihydro-2-oxo-4-quinoline propionic acid, its chemical structure is cleverly spliced from several parts. As the core structure, the quinoline ring is like the main castle of the ancient city, standing firmly in the center. At the 4th position of the quinoline ring, the propionic acid side chain is connected, just like the passage extended from the main castle, which is meandering. In particular, the [ (4-chlorobenzoyl) amino] group is introduced at the α position. Among them, the 4-chlorobenzoyl group, the chlorine atom is attached to the benzene ring, which is like a delicate accessory, and the benzene ring is connected to the formyl group, and the formyl group is connected to the amino group, and then connected to the alpha position. The whole structure is rigorous and orderly, and each part echoes each other. Like the ancient delicate mechanism, it affects the whole body and together constitutes this unique chemical structure, showing its unique charm and potential value in the field of organic chemistry.
    What are the physical properties of 4-Quinolinepropanoic acid, a- [ (4-chlorobenzoyl) amino] -1,2-dihydro-2-oxo-, (R) -
    (R) -alpha - [ (4-chlorobenzoyl) amino] -1,2-dihydro-2-oxo-4-quinolinic propionic acid, this is an organic compound. Looking at its physical properties, it is mostly solid at room temperature and pressure. Its melting point is crucial for determining the purity and characteristics, but the specific value varies depending on the preparation method and purity, and is roughly within a certain range.
    In terms of solubility, it exhibits a certain solubility in common organic solvents such as ethanol and dichloromethane. In ethanol, it can be moderately dissolved by virtue of intermolecular interactions. This property is very important in the separation and purification steps of organic synthesis. In water, the hydrophobic groups account for a large proportion of its structure, so the solubility is not good.
    The density of this compound is also an important physical property. Although the exact value needs to be accurately measured, it can be inferred from the structure that its density may be different from that of water, which is related to its phase distribution in the liquid-liquid reaction system.
    In addition, its appearance is often white to off-white powder, which can initially help to distinguish. At the same time, its stability is acceptable under certain conditions. However, under extreme conditions such as high temperature, strong acid, and strong alkali, the structure may change, triggering chemical reactions and causing physical properties to change.
    What is the main use of 4-Quinolinepropanoic acid, a- [ (4-chlorobenzoyl) amino] -1,2-dihydro-2-oxo-, (R) -
    (R) -alpha - [ (4-chlorobenzoyl) amino] -1,2-dihydro-2-oxo-4-quinolinpropionic acid, this compound has a wide range of uses. In medicine, it is often the key raw material for the creation of new antimalarial drugs. Malaria has a long history and is very harmful. With its unique chemical structure, this compound can precisely act on the metabolic pathway of Plasmodium, inhibit its growth and reproduction, and open up a new way for the development of antimalarial drugs.
    It is also of great value in the field of anti-inflammatory drug creation. Inflammation diseases are diverse and plague everyone. It can regulate inflammation-related signaling pathways in the body, reduce inflammation, and provide the possibility for the development of high-efficiency and low-toxicity anti-inflammatory new drugs. < Br >
    In the field of organic synthesis, as a key intermediate, it can react ingeniously with a variety of reagents to derive compounds with diverse structures. This property greatly expands the boundaries of organic synthesis, helps chemists create many novel organic molecules with special properties and uses, and pushes organic synthetic chemistry forward, laying a solid foundation for the development of materials science, medicinal chemistry and many other fields.
    What is the synthesis method of 4-Quinolinepropanoic acid, a- [ (4-chlorobenzoyl) amino] -1,2-dihydro-2-oxo-, (R) -
    To prepare (R) -alpha - [ (4-chlorobenzoyl) amino] -1,2-dihydro-2-oxo-4-quinolinopropionic acid, the method is as follows:
    First, take the appropriate starting material, carefully selected to ensure that its purity and quality are high. Based on a compound with a specific configuration, this configuration has a key impact on the reaction process and the stereochemical structure of the product.
    times, acylation reaction is performed. Mix the compound containing amino group with 4-chlorobenzoyl chloride in a suitable reaction environment. Choose a mild and selective solvent, such as dichloromethane or N, N-dimethylformamide, to make the reaction proceed smoothly. Here, the reaction temperature should be paid attention to, and it should be controlled at a low temperature, such as 0 ° C to 5 ° C, to prevent side reactions from occurring, so that the acylation reaction can occur accurately, and 4-chlorobenzoyl is introduced into the amino group.
    Furthermore, the quinoline ring system is constructed. With clever strategies, with suitable organic reactions, such as through multi-step cyclization reactions. This step requires the use of suitable catalysts or acid-base regulators to form a 1,2-dihydro-2-oxo-4-quinoline structure according to the established path. The control of the reaction conditions is of paramount importance, and the temperature and reaction time need to be accurately considered, such as the reaction temperature or rising to a moderate high temperature, in order to facilitate the efficient progress of cyclization, but also not too high to cause product decomposition or formation of impurities.
    In addition, the side chain of propionic acid is modified. At the appropriate stage, the structure of propionic acid is introduced, and the (R) configuration is ensured by stereoselective reaction. The reaction can be guided to the desired configuration with the help of chiral aids or chiral catalysts. This process requires fine monitoring, and modern analytical methods such as nuclear magnetic resonance and high performance liquid chromatography are used to observe the reaction process and product purity and configuration.
    At the end, the purification and purification of the product. After a series of reactions, the crude product is purified by recrystallization and column chromatography. A suitable solvent system is selected for recrystallization, or according to the characteristics of the product and impurities, suitable stationary and mobile phases are selected for column chromatography to obtain high purity (R) -alpha - [ (4-chlorobenzoyl) amino] -1,2-dihydro-2-oxo-4-quinolinic propionic acid.
    4-Quinolinepropanoic acid, a- [ (4-chlorobenzoyl) amino] -1,2-dihydro-2-oxo-, (R) - What is the common purity on the market
    Today there are 4 - Quinolinepropanoic acid, a - [ (4 - chlorobenzoyl) amino] - 1,2 - dihydro - 2 - oxo -, (R) - in the market, its common purity. This substance may be used in chemical and pharmaceutical related industries, but its common purity is difficult to determine. Due to different uses, production methods, and manufacturers, the purity can vary.
    If used in pharmaceuticals, high purity, or more than 98%, is often required to meet the strict quality regulations of the drug, to ensure efficacy and safety. Because the drug is related to human life, too many impurities, or adverse reactions, bad drug effect.
    In chemical synthesis experiments as raw materials, depending on the reaction demand, the purity or requirements are slightly lower, about 90% - 95%. Due to the experimental process or impurity removal steps, a certain purity is also required to avoid excessive impurities causing complex reactions and affecting product quality and yield.
    And the market supply, the purity of products from different manufacturers is uneven. Well-known large factories, with excellent craftsmanship and strict quality control, product purity may be easier to meet high standards; small factories have poor technology, poor equipment, and fluctuating product purity.
    Therefore, to know the exact common purity, you need to check the product descriptions of each supplier in detail, or consult industry insiders and professional information, in order to get a more accurate number.