As a leading 4-Quinolinecarboxamide,2-butoxy-N-[2-(diethylamino)ethyl]-,monohydrochloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
4-Quinolinecarboxamide, what is the chemical structure of 2-butoxy-N- [2- (diethylamino) ethyl] -, monohydrochloride?
This is a 4-quinoline formamide compound, which is named 2-butoxy-N- [2 - (diethylamino) ethyl] - and exists in the form of a monohydrochloride salt. Its chemical structure is as follows:
The quinoline ring is the core skeleton, which is connected to the formamide group at the 4th position. The nitrogen atom on this formamide is connected to a diethylamino-containing ethyl group, and the 2nd position has butoxy substitution. As for the monohydrochloride salt, the nitrogen atom in the molecule has a lone pair electron, which can be combined with the hydrogen ion in hydrochloric acid to form a salt.
To accurately draw its chemical structure, you can first draw the quinoline ring, which is connected to the ethyl group containing diethylamino at the 4th position, the 2nd position butoxy group, and the formamide nitrogen atom, and then consider it as a salt to clearly present the whole picture of this compound.
4-Quinolinecarboxamide, what are the physical properties of 2-butoxy-N- [2- (diethylamino) ethyl] -, monohydrochloride?
4 - Quinolinecarboxamide, 2 - butoxy - N - [2 - (diethylamino) ethyl] -, monohydrochloride, is an organic compound. Its physical properties involve its appearance, melting point, boiling point, solubility and other characteristics.
Looking at its appearance, it is often white to white crystalline powder, which is due to the orderly arrangement of molecular structures, resulting in stable crystalline morphology. Its melting point is the critical temperature at which the substance changes from solid to liquid. The melting point of this compound is specific, reflecting the strength of intermolecular forces, about [X] ° C. The melting point is related to the interaction of hydrogen bonds and van der Waals forces between molecules. The specific functional groups in this compound interact to make its melting point within a certain range.
The boiling point is the temperature at which the liquid substance converts to the gaseous state. However, because its structure contains a variety of functional groups, it is easy to decompose when heated, so it is difficult to measure its exact boiling point under normal pressure, or it needs to be explored under reduced pressure conditions.
Solubility is also an important physical property. In water, the molecule contains polar groups, such as carboxamide groups and amino hydrochloride parts, which make it water-soluble. However, the molecule also contains non-polar long carbon chains, such as butoxy groups, which cause its solubility in water to be limited. In organic solvents, such as ethanol, acetone, etc., the solubility is better than that in water because of the similar principle of miscibility between organic solvents and organic solvents. In ethanol, it can be well dissolved by virtue of hydrogen bonds and van der Waals forces. This is because the ethanol molecule interacts with the polar part of the compound to promote the dissolution process.
In addition, the density of the compound is also a characteristic. Although the specific value needs to be accurately determined by experiments, it contains carbon, hydrogen, nitrogen, oxygen and other atoms according to its molecular structure, and the structure is compact, and the density should be larger than that of water. Due to the mass of atoms in the molecule and the spatial arrangement, the unit volume mass is larger.
4-Quinolinecarboxamide, what is the use of 2-butoxy-N- [2- (diethylamino) ethyl] -, monohydrochloride?
4 - Quinolinecarboxamide, 2 - butoxy - N - [2 - (diethylamino) ethyl] -, monohydrochloride, the Chinese name is often called buquina hydrochloride. This substance has a wide range of uses and is often used as a key ingredient in anti-tumor drugs in the field of medical research and development.
In the exploration of medicine in the past, many doctors and pharmacists are committed to finding a good way to fight tumors. Because of its unique chemical structure, buquina hydrochloride can affect key links such as proliferation and metabolism of tumor cells. It can precisely act on specific targets within tumor cells, inhibit the activity of related enzymes, or interfere with the cell cycle process, so that the growth and spread of tumor cells can be effectively curbed.
Furthermore, in scientific research experiments, buquina hydrochloride is also an important tool. By studying its effect on different tumor cell lines, researchers can further understand the biological characteristics and pathogenesis of tumor cells, paving the way for the subsequent development of more efficient and specific anti-tumor drugs. And in the study of the mechanism of drug action, it can also provide many valuable references for the academic community, helping the medical field to move forward and solve the suffering of many patients.
4-Quinolinecarboxamide, what is the synthesis method of 2-butoxy-N- [2- (diethylamino) ethyl] -, monohydrochloride?
The synthesis of 4-quinoline formamide, 2-butoxy-N - [2 - (diethylamino) ethyl] -, monohydrochloride, is a key issue in the field of organic synthesis. To synthesize this substance, it is often through the channel of chemical synthesis.
The selection of starting materials is extremely important. Generally speaking, compounds containing quinoline structures are often used as groups, or quinoline derivatives with appropriate substitutions can be selected. At the same time, reagents with butoxy and ethylamine groups are also indispensable, such as halogenated hydrocarbons containing butoxy and diethylaminoethylamine, which can be linked by nucleophilic substitution reactions.
During the reaction process, it is necessary to pay attention to the control of conditions. The temperature has a great influence on the reaction rate and product selectivity. Usually, under moderate heating, the reaction can be accelerated, but too high temperature or side reactions may occur. The use of alkali is also key. Alkali can promote the occurrence of nucleophilic substitution reactions. Inorganic bases such as potassium carbonate and sodium carbonate are often selected, or organic bases such as triethylamine.
After the nucleophilic substitution reaction is completed, to obtain a single hydrochloride salt, a salt-forming reaction is required. In this process, an appropriate amount of hydrochloric acid can be used to generate the target single hydrochloride product. However, the amount of hydrochloric acid needs to be precisely regulated, and too much or too little hydrochloric acid can affect the purity and yield of the product.
At the end of the reaction, the separation and purification of the product cannot be ignored. The product can be separated from the reaction mixture by recrystallization, column chromatography, etc., and impurities can be removed to obtain high-purity 4-quinolinoformamide, 2-butoxy-N - [2 - (diethylamino) ethyl] -, monohydrochloride. In this way, following the above steps, careful handling, or successful synthesis of this substance.
4-Quinolinecarboxamide, 2-butoxy-N- [2- (diethylamino) ethyl] -, monohydrochloride What are the safety precautions?
4-Quinoline formamide, 2-butoxy-N - [2 - (diethylamino) ethyl] -, monohydrochloride, this is a specific chemical substance. Regarding the safety precautions of this substance, when used in ancient Chinese, the details are as follows:
First, this substance is potentially toxic. Its role in the body is complex, or damage the function of the viscera. If it is accidentally touched, the skin may develop rash or itching in the light, and the severe may cause ulceration. Therefore, when touching, be sure to wear protective clothing and protective gloves on your hands. If it involves the risk of eye contact, you need goggles to cover it.
Second, its chemical properties are lively. In case of hot topics, open flames, or with strong oxidizing agents, reducing agents and other specific substances, fear of violent reactions, even the risk of explosion. When storing, should choose a cool, dry and well-ventilated place, away from fire, heat sources, and can not be mixed with contraindicated substances.
Third, in the operation room, air circulation is essential. If it evaporates in a closed space, the concentration gradually accumulates, or is inhaled into the human body, damaging the respiratory and nervous systems. Ventilation equipment should be set up to ensure fresh air to prevent the accumulation of harmful gases.
Fourth, if it is accidentally contaminated during operation, emergency measures should be explained. If the skin is contaminated, rinse it with a large amount of water immediately, then wash it with soap; if it enters the eyes, rinse it with flowing water or normal saline immediately, and seek medical attention immediately; if you accidentally eat it, do not induce vomiting, and send it to the doctor as soon as possible.
Fifth, the disposal of this material should also be carried out in accordance with regulations. Do not dump it at will to prevent pollution of water and soil. It should be handed over to a professional organization in accordance with relevant laws and regulations to ensure the safety of the environment. Those who operate this object should be well aware of all safety matters, handle it carefully, and take precautions to ensure the safety of themselves and the surrounding environment.