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What is the chemical structure of 4-Oxo-1,4-dihydro-3-quinolinecarboxylic acid?
4 - Oxo - 1,4 - dihydro - 3 - quinolinecarboxylic acid is 4 - oxo - 1,4 - dihydro - 3 - quinoline carboxylic acid, which is an organic compound and belongs to quinoline derivatives. Today, in ancient Chinese, describe its chemical structure:
Among this compound, it contains the mother nucleus of quinoline. Quinoline is a fused heterocyclic compound composed of a benzene ring and a pyridine ring. In 4 - oxo - 1,4 - dihydro - 3 - quinoline carboxylic acid, at the 1,4 position of the quinoline ring, there is a unique modification. The hydrogen atom at the 1,4 position makes this part in the state of dihydrogen; and at the 4 position, it is replaced by an oxygen atom to form a carbonyl structure. The oxygen of this carbonyl group gives this compound specific chemical activity and physical properties.
Furthermore, at the 3 position, there is a carboxyl group. The carboxyl group, the group of -COOH, is also acidic. The existence of this carboxyl group greatly affects the acid-base properties and reactivity of the compound. Because it can participate in many chemical reactions, such as salt formation reactions, esterification reactions, etc.
Overall, the chemical structure of this 4-oxo-1,4-dihydro-3-quinoline carboxylic acid is composed of the quinoline parent nucleus as the group, supplemented by the special substitution of the 1,4 position and the carboxyl group of the 3 position. The interaction of each part jointly determines the unique chemical properties and reactivity of this compound. It may have important uses and research value in the fields of organic synthesis, pharmaceutical chemistry, etc.
What are the main uses of 4-Oxo-1, 4-dihydro-3-quinolinecarboxylic acid
4 - Oxo - 1,4 - dihydro - 3 - quinolinecarboxylic acid, that is, 4 - oxo - 1,4 - dihydro - 3 - quinolinecarboxylic acid, is widely used and has important applications in many fields.
In the field of pharmaceutical chemistry, it is a key intermediate in organic synthesis. With its unique chemical structure, complex and biologically active compounds can be constructed through many chemical reactions. Based on it, it can be carefully modified and modified to create various new types of drugs. For example, in the research and development of antibacterial drugs, this compound can be used as a starting material to optimize its antibacterial activity and pharmacokinetic properties by introducing specific substituents, providing a new strategy for dealing with drug-resistant bacterial infections.
In the field of materials science, it also has unique functions. Because its structure contains a conjugated system and specific functional groups, it can endow materials with special optical and electrical properties. It can be used to prepare optoelectronic materials, such as organic Light Emitting Diodes (OLEDs), solar cells, etc. In the manufacture of OLEDs, this compound participates in the construction of luminous layers, affects the luminous efficiency and color purity of materials, and contributes to the improvement of display technology performance.
In the field of chemical research, as a research object, it is helpful to further explore the mechanism of organic reactions. Due to its structural properties, it can exhibit a variety of chemical behaviors, providing an opportunity for organic chemists to understand reaction pathways, transition states and intermediates. By studying the reactions it participates in, reaction conditions can be optimized, reaction selectivity can be improved, and the development of organic synthesis chemistry can be promoted.
In the field of dye industry, due to its chromophore structure, it can be used to develop new dyes. By changing the types and positions of its substituents, the color and dyeing properties of dyes can be adjusted to meet the needs of different fiber materials and dyeing processes, and diverse dyeing effects can be achieved.
What are the synthesis methods of 4-Oxo-1,4-dihydro-3-quinolinecarboxylic acid
The synthesis method of 4-oxo-1,4-dihydro-3-quinoline carboxylic acid has been explored by many parties throughout the ages, and various methods have been applied.
First, aniline derivatives are used as starting materials. First, aniline and suitable unsaturated carbonyl compounds are subjected to condensation reactions under specific reaction conditions to construct the basic structure of the quinoline ring. In this process, the reaction temperature, pH and the ratio of reactants need to be carefully adjusted. If the temperature is too high, the product is easy to carbonize or have side reactions; if the temperature is too low, the reaction rate will be slow and take a long time. The acid-base environment is also critical, and the appropriate pH can promote the positive progress of the reaction and improve the yield of the product. After the initial formation of the quinoline ring, the specific position of the quinoline ring is oxidized and modified, and a carbonyl group is introduced to obtain 4-oxo-1,4-dihydro-3-quinoline carboxylic acid.
Second, the cyclization strategy is adopted. Select an aromatic compound with appropriate substituents and pass the ring reaction in the molecule. This path requires the help of a specific catalyst, which can effectively reduce the activation energy of the reaction and promote the rearrangement and cyclization of atoms in the molecule. In the reaction system, the choice of solvent should not be underestimated, and different solvents have an impact on the solubility and reactivity of the reactants. Reasonable selection of solvent can make the reaction smoother. After the cyclization, the functional group conversion is carried out in sequence, and the required oxygen and carboxyl groups are precisely introduced to achieve the synthesis of the target product.
Third, part of the synthesis method starts from natural products. Some natural product structures are similar to target compounds, and they are chemically modified and modified. The advantage of this approach is that the natural product structure is unique, and the reaction steps may be simplified. However, the acquisition of natural product raw materials may be limited by resources, and the structural modification needs to precisely control the reaction check points and conditions to avoid unnecessary damage to other functional groups.
All synthetic methods have their own advantages and disadvantages. In practical applications, it is necessary to weigh and choose the appropriate method according to factors such as the availability of raw materials, cost considerations, and product purity requirements, in order to achieve the high efficiency and accuracy of synthesis.
What are the physical properties of 4-Oxo-1,4-dihydro-3-quinolinecarboxylic acid?
4 - Oxo - 1,4 - dihydro - 3 - quinolinecarboxylic acid, that is, 4 - oxo - 1,4 - dihydroquinoline - 3 - carboxylic acid, the physical properties of this substance are quite unique. Its shape is mostly crystalline, white or nearly colorless, and it is pure in appearance. This substance is quite stable at room temperature and is not prone to significant chemical changes on its own.
When it comes to melting point, it is about a specific temperature range. The value of this melting point is one of its important physical characteristics and is the key basis for identifying this substance. The accurate determination of its melting point helps to determine the purity and characteristics of the substance. The solubility of
is different in common organic solvents. In some polar organic solvents, such as alcohols, there can be a certain solubility, but in non-polar organic solvents, such as alkane solvents, the solubility is very small. In water, its solubility is also limited, and this solubility is closely related to the molecular structure. The ratio and distribution of polar groups and non-polar parts in the molecule determine its solubility in different solvents.
Density is also one of its physical properties. Although it is not easy to perceive on a daily basis, it is of great significance in fine chemical operations and related theoretical studies. The determination of density can provide key data for the prediction of the behavior of the substance in the mixed system.
In addition, the crystal structure of this substance also has a significant impact on its physical properties. The molecular arrangement inside the crystal determines its optical, electrical and other potential physical properties. Through X-ray diffraction and other technical means, the crystal structure can be deeply investigated, and then the essential root of its physical properties can be understood more comprehensively. In summary, the physical properties of 4-oxo-1,4-dihydroquinoline-3-carboxylic acids are of great value in chemical research and related industrial application fields.
What is the price range of 4-Oxo-1,4-dihydro-3-quinolinecarboxylic acid in the market?
4 - Oxo - 1,4 - dihydro - 3 - quinolinecarboxylic acid, that is, 4 - oxo - 1,4 - dihydroquinoline - 3 - carboxylic acid, this product is on the market, its price is uncertain, due to multiple factors.
First, it is difficult to prepare, if the preparation method is cumbersome, requires multiple processes, rare raw materials or special conditions, its price must be high; if the preparation is easy, the process is simple, and the raw materials are easy to obtain, the price may be low.
Second, the quality of the advantages and disadvantages, high purity, high quality, can be used in high-end scientific research, pharmaceutical and other fields, the price is not cheap; impurities, the quality of the second, only for general industrial use, the price will also drop.
Third, the situation of demand and supply, if the market demand is large, but the supply is small, if the new drug research and development is urgently needed, the price will rise; if the demand is low and the supply is sufficient, the price will decline.
Fourth, the place of origin, different places of origin, due to the cost of raw materials, labor costs, transportation costs, the price is also different.
Roughly speaking, the price per gram, the low can be several yuan, the high can reach hundreds of yuan. For high-purity products used in laboratories, the price is often high; for ordinary products used in industrial batches, the price is relatively low. The specific price, when consulting the supplier in detail, varies from time to time and depends on the facts.