4 Methyl 8 Hydroxyquinoline
quinoline thiophene imidazole thiazole

4-Methyl-8-hydroxyquinoline

Taiy Chemical

    Specifications

    HS Code

    420514

    Chemical Formula C10H9NO
    Molar Mass 159.184 g/mol
    Appearance Solid
    Melting Point 148 - 150 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in ethanol, chloroform, etc.
    Odor Typical quinoline - like odor
    Stability Stable under normal conditions

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    General Information
    Where to Buy 4-Methyl-8-hydroxyquinoline in China?
    As a trusted 4-Methyl-8-hydroxyquinoline manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Methyl-8-hydroxyquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Methyl-8-hydroxyquinoline?
    4-Methyl-8-hydroxyquinoline is one of the organic compounds. It has a wide range of uses and is described in detail here.
    In the field of chemical analysis, this compound is often used as a chelating agent for metal ions. Due to its structure, hydroxyl groups and nitrogen atoms can form stable chelates with many metal ions. Taking copper ions as an example, the chelates formed by 4-methyl-8-hydroxyquinoline and copper ions have specific colors and properties, which can be used for qualitative and quantitative analysis of copper ions. This analytical method has high sensitivity and is widely used in the determination of copper content in ores, alloys and other samples.
    In the field of medicine, 4-methyl-8-hydroxyquinoline also has extraordinary performance. It has certain antibacterial and antiviral activities. In the past, doctors often used drugs containing this compound to treat some skin infections. Because it can inhibit the growth and reproduction of bacteria and viruses, it can achieve the purpose of curing diseases.
    Furthermore, in the field of materials science, 4-methyl-8-hydroxyquinoline can be used to prepare luminescent materials. Due to its special molecular structure, it can emit light of a specific wavelength when excited by a specific light. Therefore, it also plays an important role in the preparation of optoelectronic devices such as organic Light Emitting Diodes (OLEDs), and contributes a lot to improving the performance of optoelectronic devices.
    In summary, 4-methyl-8-hydroxyquinoline has important uses in many fields such as chemical analysis, medicine and materials science, and plays an indispensable role in the development of related industries.
    What are the physical properties of 4-Methyl-8-hydroxyquinoline?
    4 - Methyl - 8 - hydroxyquinoline is an organic compound with unique physical properties. It is usually in a solid state at room temperature and has a specific melting point, between 137 and 140 ° C. The melting point is the temperature at which the substance changes from the solid state to the liquid state. This property is crucial for the identification and purification of the compound.
    Its solubility is also worthy of attention. In organic solvents, such as ethanol and acetone, 4 - Methyl - 8 - hydroxyquinoline exhibits good solubility. Due to the principle of similar compatibility between organic substances, the molecular structure of the compound and the molecules of the organic solvent can form a suitable force to promote its dissolution. However, in water, its solubility is poor. Water is a polar molecule, and the molecular structure of 4-Methyl-8-hydroxyquinoline is quite different, and the interaction is weak, so it is difficult to dissolve.
    Furthermore, the appearance of 4-Methyl-8-hydroxyquinoline is mostly white to light yellow crystalline powder. This appearance feature is convenient for preliminary identification during experiments or production processes. Its color and morphology can be used as the basis for preliminary judgment of the purity and quality of the substance. If the color is abnormal or the morphology does not match, or it implies that it contains impurities or poor quality.
    In addition, the compound also has a certain volatility. Although the volatility is not strong, under specific temperature and environmental conditions, some molecules will change from solid or liquid to gaseous and escape. This property should be paid attention to during storage and use, and suitable storage conditions should be selected to prevent its volatilization loss.
    In short, the melting point, solubility, appearance and volatility of 4-Methyl-8-hydroxyquinoline are of great significance for its application in chemical research, industrial production and related fields. Researchers and users need to be familiar with and make good use of it.
    Is 4-Methyl-8-hydroxyquinoline chemically stable?
    4-Methyl-8-hydroxyquinoline is one of the organic compounds. Its chemical properties are relatively stable. This compound has a specific structure, containing a quinoline ring, with a methyl group at the 4th position and a hydroxyl group at the 8th position.
    Due to its structural characteristics, the presence of hydroxyl groups makes it hydrophilic to a certain extent, and hydroxyl groups can participate in a variety of chemical reactions, such as esterification, etherification, etc. The presence of methyl groups affects the electron cloud distribution and steric resistance of molecules, which in turn affects their chemical activity.
    Under common chemical reaction conditions, 4-Methyl-8-hydroxyquinoline is not easy to spontaneously decompose or produce violent reactions. In case of strong oxidizing agents, such as permanganate, dichromate, etc., or due to oxidation and structural changes. In case of strong acid and alkali, or due to acid-base reaction changes.
    But in general, in general storage and operating environments, as long as you avoid contact with strong oxidizing and strong acid-base substances, the chemical properties of 4-Methyl-8-hydroxyquinoline are stable, and can be stored for a long time without significant deterioration.
    What are 4-Methyl-8-hydroxyquinoline synthesis methods?
    The synthesis method of 4-methyl-8-hydroxyquinoline has been explored by many talents throughout the ages, and its methods are ingenious.
    First, using o-aminophenol and acetylacetone as starting materials, under suitable reaction conditions, the condensation reaction of the two occurs. This process requires precise control of temperature, pH and reaction time. If the temperature is too low, the reaction will be slow and difficult to proceed fully; if the temperature is too high, it will fear the growth of side reactions and affect the purity of the product. The pH is also crucial and needs to be adjusted to an appropriate range to promote the positive progress of the reaction. After the reaction is completed, the pure 4-methyl-8-hydroxyquinoline can be obtained through a series of separation and purification techniques, such as extraction and crystallization.
    Second, 8-hydroxyquinoline can also be used as the starting material and obtained by methylation. Select an appropriate methylating reagent, such as iodomethane, dimethyl sulfate, etc., and react with 8-hydroxyquinoline in the presence of suitable solvents and catalysts. In this reaction, the choice of solvent depends on the reaction rate and product yield, and the catalyst can also significantly affect the reaction process. After the reaction is completed, the target product can also be obtained through fine separation and purification operations.
    Furthermore, there are other related compounds as starting materials and synthesized by multi-step reaction. Although such methods are complicated, if each step can be precisely controlled, high-purity 4-methyl-8-hydroxyquinoline can also be obtained. And the design of multi-step reactions requires a deep mastery of the principles and skills of organic synthesis in order to skillfully construct the structure of the target molecule.
    All kinds of synthesis methods have advantages and disadvantages. In practical applications, it is necessary to carefully choose the appropriate method according to specific needs, availability of raw materials, cost considerations, etc., in order to achieve efficient, economical and environmentally friendly synthesis purposes.
    What is the price range of 4-Methyl-8-hydroxyquinoline in the market?
    4-Methyl-8-hydroxyquinoline, the price in the market varies depending on the quality and quantity and market conditions. Looking at the past market, its price often fluctuates in a certain area.
    If it is about high purity and high quality, the price per gram may be in the tens of yuan. Such a high price comes from the difficulty and wide use of its refining. In the field of scientific research, experiments require high-purity products, and the control of impurities is extremely strict, so the price is high.
    However, if it is for industrial use, the purity is slightly reduced, and the price is also reduced. Its gram price may be between a few yuan and a dozen yuan. Because industrial use has a wider tolerance for impurities, if mass production is produced, the cost will also decrease.
    And the amount purchased is also related to the price. When buying in large quantities, the supplier often gives it at a preferential price, with small profits but quick turnover, in order to promote transactions. For small buyers, the price may be slightly higher.
    The supply and demand of the market are also the key to the price. When demand exceeds supply, the price will rise; if supply exceeds demand, the price will fall. In the past, due to some reasons, the supply was low, and the price increased significantly; after the production capacity rose, the demand did not change greatly, so the price fell steadily. < Br >
    In summary, the price of 4-methyl-8-hydroxyquinoline varies from a few yuan to tens of yuan per gram, and the actual price should be obtained according to the specific situation.