4 Hydroxy 2 Methylquinoline
quinoline thiophene imidazole thiazole

4-Hydroxy-2-methylquinoline

Taiy Chemical

    Specifications

    HS Code

    912752

    Chemical Formula C10H9NO
    Molecular Weight 159.184 g/mol
    Appearance Solid
    Melting Point 109 - 111 °C
    Boiling Point 307.2 °C at 760 mmHg
    Density 1.167 g/cm³
    Solubility In Water Insoluble
    Flash Point 139.6 °C
    Pka 8.49
    Refractive Index 1.647

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    General Information
    Where to Buy 4-Hydroxy-2-methylquinoline in China?
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    Frequently Asked Questions

    As a leading 4-Hydroxy-2-methylquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 4-Hydroxy-2-methylquinoline?
    4-Hydroxy-2-methylquinoline, which is also an organic compound. Its chemical properties are unique and valuable to explore.
    First, because it contains hydroxyl groups, it is acidic to a certain extent. Hydrogen atoms of hydroxyl groups can be dissociated under suitable conditions and can react with bases to form corresponding salts. For example, when encountering strong bases such as sodium hydroxide, sodium salts can be formed, and this reaction exhibits its acidic characteristics.
    Furthermore, the quinoline ring structure in the molecule gives it a certain aromaticity. Aromatic rings are stable and can undergo many aromatic electrophilic substitution reactions. For example, in halogenation reactions, under the action of appropriate catalysts, halogen atoms can replace hydrogen atoms on the ring; in nitration reactions, nitro groups can also be introduced into the quinoline ring, which is due to the electron cloud distribution characteristics of the aromatic ring.
    In addition, the methyl group at the 2-position also affects its chemical properties. Methyl as the power supply group can increase the electron cloud density of the quinoline ring, which in turn affects the check point and activity of the electrophilic substitution reaction, making the reaction more susceptible to the specific position affected by the electron effect of methyl.
    At the same time, 4-hydroxy-2-methylquinoline may also participate in the redox reaction. Hydroxyl groups can be oxidized to oxygen-containing functional groups with higher valence states such as carbonyl groups, and quinoline rings may also undergo hydrogenation and reduction reactions under the action of specific strong reducing agents.
    In short, 4-hydroxy-2-methylquinoline has various chemical properties due to its functional groups and unique ring structure, and may have important uses in organic synthesis and medicinal chemistry.
    What are the common synthetic methods of 4-Hydroxy-2-methylquinoline?
    4-Hydroxy-2-methylquinoline is also an organic compound. There are several common synthesis methods.
    First, o-aminophenone and ethyl acetoacetate are used as raw materials, and can be obtained through the steps of condensation and cyclization. First, in the presence of an appropriate catalyst, the condensation reaction of o-aminophenone and ethyl acetoacetate is carried out. This reaction requires controlling the temperature and reaction time, and selecting a suitable solvent, such as ethanol, to promote the effective binding of the two. Then, the condensation product is cyclized to form the structure of 4-hydroxy-2-methylquinoline.
    Second, aniline and acetylacetone can also be used as starting materials. Aniline and acetylacetone are condensed first, and then cyclized under specific conditions. In this process, the choice of catalyst is crucial, and different catalysts have an impact on the reaction rate and yield. And the reaction conditions need to be precisely regulated, such as temperature and pressure.
    There are other similar compounds as starting materials that are converted into 4-hydroxy-2-methylquinoline through a series of reactions. However, no matter what method, it is necessary to pay attention to the purity of the raw materials and the optimization of the reaction conditions, so that the product with higher yield and purity can be obtained. When synthesizing, it is also necessary to pay attention to the safety of the reaction to avoid dangerous situations. All synthesis methods have advantages and disadvantages. According to actual needs and conditions, choose the appropriate method.
    In what areas is 4-Hydroxy-2-methylquinoline applied?
    4-Hydroxy-2-methylquinoline is useful in various fields.
    In the field of medicine, this compound has attracted much attention. Because of its specific chemical structure, it can be combined with specific targets in organisms, so it can be a lead compound in drug development. Many studies have investigated its pharmacological activity, hoping to use its structure to create novel drugs for the treatment of diseases. For example, it may be possible to use its effect on specific biological enzymes to develop drugs for certain inflammatory diseases and tumor diseases to achieve the purpose of precision treatment.
    In the field of materials science, 4-hydroxy-2-methylquinoline can also be used. Due to its structure, it gives it unique physical and chemical properties, or it can be used to prepare functional materials. For example, in optical materials, it may have specific fluorescence properties, which can be applied to the preparation of fluorescent probes. In the field of biological imaging, it can help researchers gain insight into the microstructure and biochemical processes in organisms, and add to life science research.
    Furthermore, in the world of organic synthesis, 4-hydroxy-2-methylquinoline is an important intermediate. Using it as a starting material, chemists can build more complex organic molecular structures through various organic reactions. Through ingenious reaction design, a series of organic compounds with special functions or structures are synthesized, which are widely used in the preparation of fine chemical products, such as fragrances, dyes, etc., adding to the enrichment and development of the chemical industry.
    From this point of view, 4-hydroxy-2-methylquinoline has shown its unique value and broad application prospects in many fields such as medicine, materials science, organic synthesis, etc., and is indispensable for scientific research and industrial development.
    What are the physical properties of 4-Hydroxy-2-methylquinoline?
    4-Hydroxy-2-methylquinoline is one of the organic compounds. Its physical properties are quite special, so let me tell you in detail.
    This compound is usually in the form of a solid state. Looking at its color, it often appears light yellow to light brown, like the first color of autumn wood leaves, delicate and soft. Its melting point is about a specific numerical range, specifically, about [X] ° C. This temperature limit is just like the cardinal of the transformation of the state of matter, causing it to gradually melt from solid to liquid when heated.
    As for the boiling point, it also has its inherent value, which is about [X] ° C, which is just like the critical point for the boiling and dissipation of matter. At this temperature, 4-hydroxy-2-methylquinoline will turn into gaseous ascension. And its density is about [X] g/cm ³, so the density occupied by space is considerable.
    In terms of solubility, 4-hydroxy-2-methylquinoline shows different affinity in common organic solvents. In organic solvents such as ethanol and acetone, it can be moderately dissolved, just like a fish in water, and it blends seamlessly; however, in water, its solubility is relatively limited, only slightly soluble, such as panning for gold in sand, and obtaining a small amount of it.
    Its volatility is very small. Under normal temperature and pressure, it rarely evaporates and is lost in the air. It seems to be calm and not easy to disperse. The smell is also very weak. If it is not deliberately sniffed, it is almost invisible, like a faint fragrance, hidden in the invisible.
    In addition, 4-hydroxy-2-methylquinoline has a certain stability. Under normal environmental conditions, it is not prone to violent chemical changes. It is like a quiet stone, and it is stable and alone. In case of extreme chemical environments such as strong acids and alkalis, its structure may change, which requires caution.
    What is the market price of 4-Hydroxy-2-methylquinoline?
    4-Hydroxy-2-methylquinoline, this is an organic compound. As for its market price, it is difficult to tell. Due to the unpredictable market conditions, it is affected by many factors.
    First, the state of supply and demand is the key. If the demand for this substance is strong and the supply is limited, such as in the field of pharmaceutical research and development or in specific chemical production, the demand for it will increase sharply, and the output will not be expanded accordingly, the price will rise. On the contrary, if there is little demand and excess supply, the price may decline.
    Second, the cost of production also affects the price. The price of raw materials, the simplicity of production processes, and the amount of energy consumption are all cost factors. If raw materials are scarce and expensive, or the production process requires high-precision technology and expensive equipment, resulting in soaring costs, prices will also rise.
    Third, the market competition situation should not be underestimated. If there are many producers and the competition is fierce, in order to compete for market share, prices may be reduced; however, if the market is almost monopolized, or there are only a few suppliers, prices will be easily controlled by them.
    Fourth, the macroeconomic environment, policies and regulations also have an impact. The economy is prosperous, the market is active, and prices may rise; policies are strict on environmental protection, production qualifications, etc., resulting in increased production costs, which will also drive up prices. Therefore, if you want to know the exact market price of 4-hydroxy-2-methylquinoline, you should pay close attention to the market trends of chemical raw materials, consult relevant suppliers, distributors, or refer to professional chemical product price information platforms to obtain more accurate price information.