4 Fluoro 5 Isoquinolinesulfonylchloridehydrochloride
quinoline thiophene imidazole thiazole

4-Fluoro-5-isoquinolinesulfonylchloridehydrochloride

Taiy Chemical

    Specifications

    HS Code

    231953

    Chemical Formula C9H5Cl2FNO2S
    Molecular Weight 282.11
    Appearance Solid (Typical)
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents
    Melting Point Data needed
    Boiling Point Data needed
    Purity Varies by source
    Density Data needed
    Stability Reacts with water and bases, should be stored properly

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    General Information
    Where to Buy 4-Fluoro-5-isoquinolinesulfonylchloridehydrochloride in China?
    As a trusted 4-Fluoro-5-isoquinolinesulfonylchloridehydrochloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Fluoro-5-isoquinolinesulfonylchloridehydrochloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    4-Fluoro-5-isoquinolinesulfonyl What are the chemical properties of hydrochloride?
    4-Fluoro-5-isoquinoline sulfonyl chloride, this is a very important organic compound. Its physical properties are unique, it is often solid at room temperature, white or white, mostly in powder form, because it contains hydrochloride components, it has a certain degree of hygroscopicity, and it is easy to agglomerate in case of moisture.
    In terms of chemical properties, its chemical activity is quite high. Sulfonyl chloride groups are extremely active and easily react with many nucleophiles. In case of alcohols, a substitution reaction can occur to generate corresponding sulfonates; when it meets amines, sulfonamides will be formed. This reactivity makes it widely used in the field of organic synthesis and is often regarded as a key intermediate for the preparation of a variety of complex organic compounds.
    The presence of fluorine atoms also significantly affects its chemical properties. Fluorine atoms are highly electronegative, which can change the distribution of molecular electron clouds, enhance molecular stability and fat solubility. In the field of medicinal chemistry, this property can help improve the biological activity and pharmacokinetic properties of drugs.
    However, this compound is corrosive to a certain extent, and careful protection is required when contacting. The operation should be carried out in a well-ventilated environment to prevent harm to the human body and the environment.
    4-Fluoro-5-isoquinolinesulfonyl the main uses of hydrochloride
    4-Fluoro-5-isoquinoline sulfonyl chloride has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate in organic synthesis. Gein isoquinoline structure is common in many drug molecules, and the physical, chemical and biological activities of compounds can be significantly changed by introducing fluorine atoms and sulfonyl chloride groups. For example, when developing new anti-tumor drugs, its structural properties can be combined with specific biological targets to hinder the proliferation and metastasis of tumor cells, providing an effective way to overcome cancer problems.
    In the field of materials science, it also has extraordinary performance. Because it contains active chlorine atoms and sulfonyl groups, it can chemically react with many polymer materials, thereby modifying the surface of materials. For example, when preparing high-performance polymer films, adding an appropriate amount of the compound can enhance the hydrophilicity and antistatic properties of the film, and broaden the application of polymer materials in electronics, packaging and other fields.
    In the field of organic synthetic chemistry, it plays an indispensable role. As a sulfonylation reagent, it can react with various nucleophiles to realize the synthesis of sulfonamides, sulfonates and other important organic compounds. With its unique reactivity and selectivity, it can provide organic synthesis chemists with efficient methods for constructing complex organic molecular structures, and help create new functional materials and bioactive molecules.
    What is the synthesis method of 4-Fluoro-5-isoquinolinesulfonyl chloride hydrochloride?
    The synthesis of 4-fluoro-5-isoquinoline sulfonyl chloride is a key research topic in the field of organic synthesis. The synthesis of this compound often requires multiple and delicate reactions.
    The first step may require careful selection of suitable starting materials, such as isoquinoline derivatives with specific substituents. This starting material needs to be precisely designed to ensure that subsequent reactions can proceed smoothly and obtain the basic skeleton required for the target product.
    Next, fluorine atoms can be introduced at specific positions in the isoquinoline ring by means of electrophilic substitution reactions. This step requires careful regulation of reaction conditions, such as temperature, reaction duration, and catalyst used. Due to the unique electronic and spatial effects of fluorine atoms, its introduction location and efficiency have a significant impact on subsequent reactions and the properties of the final product.
    Then, the introduction of sulfonyl chloride groups is also crucial. Generally, it can be achieved by interacting with sulfur-containing reagents, such as sulfuryl chloride, under suitable reaction conditions. This reaction requires attention to the selectivity of the reaction to avoid side reactions and damage to the purity of the product.
    Finally, hydrochloride is formed. Usually, the resulting product can be reacted with hydrogen chloride gas or hydrochloric acid solution in a suitable solvent. This process should control the degree of reaction to ensure that the generated hydrochloride salt is well crystallized and easy to separate and purify. During the
    synthesis process, each step of the reaction needs to be strictly monitored. Thin-layer chromatography (TLC), nuclear magnetic resonance (NMR) and mass spectrometry (MS) are commonly used to confirm the reaction progress and product structure. At the same time, the optimization of reaction conditions is also indispensable to improve the yield and product purity.
    4-Fluoro-5-isoquinolinesulfonyl chloride hydrochloride what to pay attention to when storing and transporting
    4-Fluoro-5-isoquinoline sulfonyl chloride hydrochloride, this is a chemical substance. When storing and transporting, many aspects need to be carefully paid attention to.
    When storing, the temperature and humidity of the first environment. It should be placed in a cool and dry place. Due to excessive temperature or humidity, its chemical properties can change. For example, if high temperature may cause decomposition, humid environment or deliquescence, which will damage its purity and quality.
    Furthermore, it must be avoided to mix with other chemicals. This substance has certain chemical activity and is in contact with certain oxidants, reducing agents or alkalis. It is prone to chemical reactions or dangerous accidents, such as explosion, fire, etc.
    Packaging is also crucial. Well-sealed packaging materials should be selected to prevent air and water vapor from invading. Glass containers or plastic containers with special coatings are often suitable to effectively maintain their stability.
    When transporting, safety protection is the key. Transportation personnel must be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. Transportation vehicles should also be equipped with corresponding fire and leakage emergency equipment.
    And during transportation, ensure that the container is stable and prevent collision and dumping from causing leakage. If a leak unfortunately occurs, it should be dealt with promptly according to the established emergency plan, evacuate the surrounding personnel, isolate the contaminated area, and collect or adsorb with suitable materials to avoid polluting the environment and endangering human health. In this way, the safety of 4-fluoro-5-isoquinoline sulfonyl chloride storage and transportation is guaranteed.
    What is the market price of 4-Fluoro-5-isoquinolinesulfonyl chloride hydrochloride?
    4-Fluoro-5-isoquinoline sulfonyl chloride hydrochloride, this substance is in the market, its price is variable, due to many reasons. In the past, when "Tiangong Kaiwu" talked about all kinds of things, it was said that its price varies according to quality, quantity, time and place, and the same is true for this chemical substance.
    If its quality is pure, free of impurities and flaws, the price must be high. On the contrary, if it contains impurities and damages its performance, the price should be low. Quantity is also important. If you buy in bulk, the business is for profit, or you can give a discount, and the unit price will drop; if you only ask for a small amount, for research and testing, the price may be expensive.
    The impact is also great. The supply and demand in the city are balanced, and the price is stable; if there are many people who need it, but the supply is insufficient, the price will rise; if the supply exceeds the demand, the price will fall. The distance of the place also affects the price. The origin is close, the freight is provincial, and the price may be appropriate; if the freight increases far away, the price will also be higher.
    As for the exact price, it is difficult to have a fixed number. In the chemical industry city, or consult various merchants, to know the current price. Or dozens of yuan per gram, or more than 100 yuan, are unknown, and must be investigated in real time.