4 Chloro 7 Methoxyquinoline
quinoline thiophene imidazole thiazole

4-Chloro-7-methoxyquinoline

Taiy Chemical

    Specifications

    HS Code

    661356

    Chemical Formula C10H8ClNO
    Molecular Weight 193.63
    Appearance Solid (usually a powder or crystalline solid)
    Color Typically white to off - white
    Odor Odorless or faint odor
    Melting Point Data may vary, but generally in a certain range (check literature for exact value)
    Boiling Point Requires further experimental determination or literature search for exact value
    Solubility In Water Poorly soluble in water
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
    Density Literature - specific value needed for accurate determination
    Pka Value depends on the acidic or basic nature of relevant functional groups in the molecule (literature - based)

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    General Information
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    Frequently Asked Questions

    As a leading 4-Chloro-7-methoxyquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 4-chloro-7-methoxyquinoline?
    4-Deuterium-7-methoxybenzaldehyde is an organic compound. Its physical properties are as follows:
    Looking at its properties, at room temperature, 4-deuterium-7-methoxybenzaldehyde is mostly in a solid state, or a crystalline state. When the quality is pure, the color is close to colorless, but it may be slightly yellowish due to impurities.
    When it comes to the melting point, the melting point is about a specific numerical range. This value varies slightly due to differences in accurate measurement conditions. It is roughly within a certain range. Its boiling point is also at the corresponding temperature, which is determined by factors such as intermolecular forces. There is a van der Waals force between molecules, and the melting boiling point is also affected by polar groups and hydrogen bonds.
    As for solubility, in organic solvents, such as ethanol, ether, etc., 4-deuterium-7-methoxybenzaldehyde exhibits good solubility. Due to its molecular structure, there are both lipophilic benzene ring parts and methoxy groups with certain polarity, so it can interact with organic solvents and be dissolved. However, in water, its hydrophobic benzene ring accounts for a large proportion, and its solubility is not good.
    Its density is also a specific value, which reflects its mass per unit volume. Compared with other related compounds, it has a unique density performance due to its molecular composition and packing method.
    In addition, 4-deuterium-7-methoxybenzaldehyde has optical properties. Due to the existence of the conjugate system of the benzene ring, under the irradiation of light of a specific wavelength, it can exhibit the characteristics of absorption spectrum. This property is of great practical value when analyzing and identifying this compound. Its vapor pressure also changes accordingly at different temperatures. When the temperature increases, the vapor pressure increases, reflecting the difficulty of volatilization.
    What are the chemical properties of 4-chloro-7-methoxyquinoline?
    4-Cyanogen-7-methoxybenzaldehyde is an organic compound with the following chemical properties:
    1. ** Reaction of aldehyde groups **:
    - ** Oxidation reaction **: The aldehyde group can be oxidized. When encountering weak oxidants such as Torun reagent (silver ammonia solution), a silver mirror reaction can occur. The aldehyde group is oxidized to a carboxyl group, and the silver element is reduced by itself, that is, a bright silver mirror is formed. The reaction formula is: 4-cyanogen-7-methoxylbenzaldehyde + 2 [Ag (NH (NH) ³] OH → 4-cyanogen-7-ammonium methoxylbenzoate + 2Ag? + 3NH? + H? O; when encountering strong oxidants such as acidic potassium permanganate solution, the aldehyde group can also be oxidized to a carboxyl group, causing the potassium permanganate solution to fade. < Br > - ** Reduction reaction **: The aldehyde group can be reduced to hydrogen as a reducing agent. Under the action of catalysts such as nickel and palladium, the aldehyde group can be reduced to an alcohol hydroxyl group to generate 4-cyanogen-7-methoxybenzyl alcohol.
    - ** Addition reaction **: The carbon and oxygen double bonds in the aldehyde group can be added. Under the catalysis of acids, acetals can react with alcohols to generate acetals. Taking ethanol as an example, the reaction is formed into hemi-acetals, which in turn generate acetals. This reaction is often used to protect aldehyde groups in organic synthesis.
    2. ** Reaction of cyanyl group **:
    - ** Hydrolysis reaction **: Cyanyl group can be hydrolyzed under acidic or alkaline conditions. Under acidic conditions, cyanyl group is gradually hydrolyzed to amide, and then further hydrolyzed to carboxylic acid, that is, 4-carboxyl-7-methoxybenzaldehyde can be obtained by cyanohydrolysis of 4-carboxylic-7-methoxybenzaldehyde; under alkaline conditions, hydrolysis produces carboxylic salts, and the corresponding carboxylic acid is obtained after acidification.
    - ** Nucleophilic addition reaction **: The carbon atoms in the cyanyl group are electrophilic and can be added with nucleophilic reagents. If it reacts with Grignard reagents, it is first added to form an intermediate product. After hydrolysis, alcohols containing different substituents can be obtained, which can be used for carbon chain growth and structural modification in organic synthesis.
    3. ** Reaction of benzene ring **:
    - ** Substitution reaction **: The benzene ring is aromatic and can undergo electrophilic substitution reaction. Because it contains methoxy and cyano, methoxy is an ortho-para-site group and cyano is an meta-site group. Under the combined influence of the two, the substitution reaction mainly occurs in the ortho and para-sites of methoxy groups. If a halogenation reaction occurs, under the catalysis of iron or iron halide, it can react with halogen elements to form halogenated products; when a nitration reaction occurs, a nitro group can be introduced under the action of a mixed acid of concentrated sulfuric acid and concentrated nitric acid.
    What are the main uses of 4-chloro-7-methoxyquinoline?
    4-Alkane-7-methoxybenzaldehyde is a valuable class of organic compounds. Its main uses are various, and this is described in detail by you.
    In the field of pharmaceutical chemistry, this compound is often a key intermediate for the synthesis of many drugs. With its unique chemical structure, it can be used to supplement or modify specific functional groups by chemical synthesis, and then obtain drug molecules with specific pharmacological activities. For example, some drugs with antibacterial and anti-inflammatory effects often use 4-alkane-7-methoxybenzaldehyde as the starting material in their synthesis path. After multi-step chemical reactions, the core structure of the drug is carefully constructed, providing an important material basis for pharmaceutical research and development. < Br >
    In the field of materials science, it also shows its unique function. It can be used to prepare materials with special optical and electrical properties. Due to its molecular structure, it can produce specific responses to light and electricity, and can be prepared through appropriate chemical modification and material processing techniques, such as organic photoconductors, fluorescent materials, etc. These materials play an important role in optoelectronic devices, such as Light Emitting Diode, solar cells, etc., helping to improve the performance and efficiency of devices.
    In the fragrance industry, 4-alkane-7-methoxybenzaldehyde can be added to various flavors as a fragrance component due to its special odor. The aroma it emits is unique and elegant, which can give a unique fragrance to the essence. It is widely used in perfumes, cosmetics, air fresheners and other products to add the aroma charm of the product and enhance the sensory experience of consumers.
    In summary, 4-alkane-7-methoxybenzaldehyde plays an indispensable role in many fields such as medicine, materials, and fragrances, and has made great contributions to the development of various industries.
    What is the synthesis method of 4-chloro-7-methoxyquinoline?
    To prepare 4-cyanogen-7-methoxybenzaldehyde, you can follow the following ancient method.
    First take an appropriate amount of starting material, based on benzene compounds, and subtly introduce methoxy groups into it. In this step, a suitable halogenated methane can be selected, and under the catalysis of a base, it interacts with a benzene substrate. When choosing a base, considering its alkalinity and the mildness of the reaction, such as potassium carbonate, in an organic solvent, stir at controlled temperature to make the methyl group of the halogenated methane and the hydroxyl group on the benzene ring smoothly form an ether to obtain a benzene derivative containing methoxy.
    Then, a cyanyl group is introduced into the methoxylation product. The halogenate is often reacted with cyanide. The methoxylated benzene derivative is first halogenated, and a halogenating agent such as phosphorus trihalide or halogenated sulfoxide can be used to replace the hydrogen at a specific position in the benzene ring with halogen to obtain the halogenated methoxylbenzene derivative. Then, cyanides such as sodium cyanide or potassium cyanide are taken and reacted with the halogenated product in an appropriate solvent with the help of a phase transfer catalyst. The phase transfer catalyst can promote the ionic cyanide to cross the two-phase interface and undergo nucleophilic substitution with the halogen. The cyanyl group successfully replaces the halogen to obtain the 4-cyanide-7-methoxylbenzene intermediate.
    Finally, this intermediate is oxidized to form an aldehyde group. A mild oxidizing agent, such as manganese dioxide or active manganese dioxide, can be used in an organic solvent system to control the temperature. During the reaction process, the methyl group of the cyano ortho position is oxidized into an aldehyde group, and the final product is 4-cyano-7-methoxybenzaldehyde. After the reaction is completed, the pure product can be obtained by extraction, distillation, recrystallization and other purification methods. Each step needs to be precisely controlled by temperature and time, and pay attention to the ratio of raw materials to achieve the purpose of efficient reaction and pure product.
    What should be paid attention to when storing and transporting 4-chloro-7-methoxyquinoline?
    The light of 4-alkane-7-methoxybenzoic acid, when storing and transporting, many matters must be paid attention to.
    First environmental conditions. This light-sensitive material should be stored in a cool, dry and dark place. Light can easily cause chemical reactions to occur and damage its quality. The temperature of the warehouse should be stable in a suitable range, not too high or too low, to prevent changes in its properties due to drastic changes in temperature. Humidity cannot be ignored. Too wet is easy to breed mold, etc., which affects its purity.
    Furthermore, the packaging must be tight. It should be properly wrapped in suitable packaging materials, such as containers with good light protection and good sealing. In this way, it can not only block the intrusion of external light, but also prevent the entry of external moisture and impurities. During transportation, the packaging must be stable to avoid package damage due to bumps and collisions, and expose light to unfavorable environments.
    During transportation, it is crucial to choose the appropriate transportation method. The transportation environment of high temperature, high humidity and strong vibration should be avoided. If land transportation is used, when the high temperature in summer, the transportation vehicle should have temperature control equipment to prevent the temperature inside the vehicle from being too high. When water transportation, it is also necessary to prevent the goods from being damp. And during transportation, when regularly checking the condition of the goods to ensure that the packaging is not damaged and the quality has not changed.
    When handling, the operator must handle it with care. This light may be dangerous, and improper operation may cause safety accidents. Operators should receive professional training, be familiar with their characteristics and precautions, and operate in strict accordance with standardized procedures to ensure the safety of personnel and the integrity of goods.