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What is the main use of 4-Chloro-7- (3-chloropropoxy) -3-cyano-6-methyloxyquinoline?
4-Chloro-7- (3-chloropropoxy) -3-cyano-6-methoxyquinoline is a key ingredient in the field of pharmaceutical and chemical industry.
It is often a key intermediate in the synthesis of drugs. Because of its special chemical structure, it contains functional groups such as chlorine atoms, cyano groups, methoxy groups and propoxy groups, which can be combined with other compounds through various organic reactions, such as nucleophilic substitution, electrophilic substitution, etc., to build more complex drug molecular structures. Taking the creation of drugs for the treatment of specific diseases as an example, through the modification and transformation of their structures, substances with unique pharmacological activities may be obtained, which can accurately act on lesion targets or regulate physiological metabolic pathways, so as to achieve the purpose of treating diseases.
In the process of pesticide research and development, it also plays an important role. Because of its chemical stability and specific biological activity, or it can be appropriately modified and formulated to make high-efficiency and low-toxicity pesticide varieties. Such pesticides may show good killing or inhibitory effects against specific pests and pathogens, and have little impact on the environment, which is in line with the development demands of modern agriculture for green and environmental protection.
In addition, in the field of materials science, it may also have potential uses. Its structural properties may endow materials with specific physical and chemical properties, such as optical and electrical properties, providing new ideas and raw material selection for the research and development of new functional materials, and promoting the innovation and development of new materials.
What are the synthesis methods of 4-Chloro-7- (3-chloropropoxy) -3-cyano-6-methyloxyquinoline
The synthesis method of 4-chloro-7- (3-chloropropoxy) -3-cyano-6-methoxyquinoline is not directly recorded in "Tiangong Kaiwu", but the idea of ancient chemical technology can be used to simulate the preparation path of similar compounds to deduce.
Ancient chemical technology often relies on natural materials such as ores and plants. When synthesizing this compound, the natural cyanyl-containing ore can be used first. After roasting and refining, the cyanyl raw material can be obtained. For example, the ancients smelted copper, and the copper-containing ore was roasted in the furnace at high temperature, so that the impurities in the ore evaporated to obtain purer copper. Similarly, the cyanide-containing ore is roasted to obtain pure cyanide, which is the initial step for the introduction of cyanide groups in the synthesis.
The construction of quinoline rings can refer to the ancient recipe for the preparation of heterocyclic compounds. In ancient times, plant bases were used as raw materials and the heterocyclic structure was constructed by chemical reaction. In this case, suitable plant extracts containing methoxy groups can be selected to react with chlorine-containing compounds with specific solvents and conditions. For example, in ancient winemaking, grains were used as raw materials and fermented under the action of koji to obtain wine. This reaction may require a specific temperature and time to rearrange and combine the chemical bonds of the two to form the initial shape of the quinoline ring.
As for the introduction of chloropropoxy, it can be modelled on the ancient method of modifying organic compounds. In ancient times, soap was obtained by reacting oil and base, which was a modification of the oil structure. Here, the constructed quinoline derivative can be reacted with 3-chloropropanol in the presence of an appropriate basic catalyst for nucleophilic substitution. Control the reaction temperature and material ratio, so that 3-chloropropoxy can be successfully connected to the 7th position of the quinoline ring to obtain 4-chloro-7- (3-chloropropoxy) - 3-cyano-6-methoxyquinoline. However, these are all speculations that simulate ancient methods and are practical for modern synthesis. They need to be optimized and verified in detail according to modern chemical theories and technologies.
What are the physical properties of 4-Chloro-7- (3-chloropropoxy) -3-cyano-6-methyloxyquinoline
4-Chloro-7- (3-chloropropoxy) -3-cyano-6-methoxyquinoline is an organic compound with unique physical properties.
Looking at its properties, at room temperature, it is mostly solid, or nearly white, or like white, which is slightly different due to its purity and crystal form. Its texture is fine, often in the state of powder, and it feels delicate to the touch.
When it comes to the melting point, it has been strictly determined to be around [X] ° C. The melting point is also the critical temperature at which the substance changes from solid to liquid. This property is crucial in the identification and purification of substances. Due to the differences in melting points of different organic compounds, it is like a human fingerprint and is unique.
In addition, its solubility shows a certain solubility in common organic solvents, such as ethanol and acetone. In ethanol, when it is slightly hot, it gradually dissolves and forms a uniform solution. This is due to the interaction between the polarity of ethanol and the partial groups of the compound. In water, its solubility is very small. Due to the relatively weak polarity of the compound molecule, the force between it and the water molecule is insufficient, and it is difficult to blend.
Its density is also one of the important physical properties. After accurate measurement, it is about [X] g/cm ³. Density is related to the mass per unit volume of a substance. This value is of important reference value for the measurement, transportation and related process design of materials.
As for its stability, it is quite stable under conventional environmental conditions. However, in case of hot topic, open flame or strong oxidant, you need to pay more attention. Hot topic or cause the breaking of chemical bonds in the molecule, triggering a decomposition reaction; open flame may cause it to burn; contact with strong oxidants can easily induce oxidation reactions, resulting in changes in the structure and properties of the compound.
To sum up, the physical properties of 4-chloro-7- (3-chloropropoxy) -3-cyano-6-methoxyquinoline play an indispensable role in many fields such as chemical research and industrial production. In-depth understanding and grasp of it is actually the key to the proper use of this compound.
What are the chemical properties of 4-Chloro-7- (3-chloropropoxy) -3-cyano-6-methyloxyquinoline
4-Chloro-7- (3-chloropropoxy) -3-cyano-6-methoxyquinoline is an organic compound. Its chemical properties are unique and valuable for investigation.
First of all, its stability is relatively stable under normal temperature and pressure. However, in case of high temperature, open flame or strong oxidant, it may cause chemical reactions, and even there is a risk of combustion and explosion. Because its structure contains cyano groups, this is a relatively active functional group. Under specific conditions, hydrolysis and addition reactions can occur. When hydrolyzed, the cyanyl group can be converted into carboxyl or amide groups, and this process often needs to be carried out in acidic or alkaline environments.
Furthermore, the characteristics of the halogen atom also have a great influence on the compound. The presence of chlorine atoms in the molecule makes it have a certain nucleophilic substitution reaction activity. In the presence of appropriate nucleophiles, chlorine atoms can be replaced by other groups, such as hydroxyl groups, amino groups, etc., resulting in the generation of many new compounds. This property is widely used in the field of organic synthesis.
In addition, methoxy groups, as a donator group, can affect the electron cloud density distribution on the quinoline ring and affect its chemical properties. The quinoline ring itself has a certain aromaticity, which enables the compound to undergo typical reactions of aromatic compounds such as electrophilic substitution reactions. Under appropriate conditions, other functional groups can be introduced into the quinoline ring to expand its chemical uses.
In summary, the chemical properties of 4-chloro-7- (3-chloropropoxy) -3-cyano-6-methoxyquinoline are rich and diverse, and it has potential application prospects in organic synthesis and related fields. However, its reactivity also needs to be treated with caution during use to ensure the safety and effectiveness of the operation.
What is the price range of 4-Chloro-7- (3-chloropropoxy) -3-cyano-6-methyloxyquinoline in the market?
I think this 4-chloro-7- (3-chloropropoxy) -3-cyano-6-methoxyquinoline is a fine chemical product. In the category of market price, it is difficult to set it abruptly. The price often varies due to multiple factors, such as the cost of raw materials, production process, market supply and demand, and quality.
If it is a raw material, the price of the various chemicals required for its preparation may vary depending on the origin, season, and market fluctuations. If the required chlorine, cyanide, methoxy and other related raw materials are in short supply at the origin of the raw materials, or the output is sharply reduced due to natural and man-made disasters, the price will rise, and the cost of this 4-chloro-7- (3-chloropropoxy) -3-cyano-6-methoxyquinoline will also rise, and the market price will also rise.
In addition, if the production process adopts advanced and efficient methods, although the equipment investment is quite large at the beginning, in the long run, energy consumption and yield can be reduced, the cost may be reduced, and the price can also be reduced; on the contrary, if the process is outdated, energy consumption is high, output is low, the cost will be high, and the price will also be high.
The relationship between market supply and demand is also the main reason for the price. If the demand for this compound in the fields of medicine, pesticides, etc. increases sharply, but the supply is limited, the price will rise; if the market oversupply, merchants will sell their goods or compete to reduce the price.
The quality also affects the price. Those with high purity and high quality are more popular in high-end application scenarios and have a higher price; those with inferior quality can only be used in places with lower requirements, and the price is low.
Overall, the market price of this 4-chloro-7- (3-chloropropoxy) -3-cyano-6-methoxyquinoline is intertwined due to the above factors, or fluctuates between tens of yuan and hundreds of yuan per kilogram. It is difficult to determine a fixed category.