4-Chloro-7-(3-Chloro-Propoxy)-6-Methoxy-Quinoline-3-Carbonitrie

4-Chloro-7- (3-chloropropoxy) -6-methoxyquinoline-3-formonitrile is one of the organic compounds. Its main use is quite extensive, in the field of medicinal chemistry, often as a key intermediate, can be used to create new drugs. Because of its unique chemical structure, it can interact with specific targets in organisms, or participate in the key steps of drug synthesis, helping to develop drugs with specific curative effects, such as antibacterial, anti-tumor drugs, etc.
In the field of pesticide chemistry, it also has important uses. It can be reasonably modified and modified to have biological activities such as insecticidal, bactericidal or herbicidal. Pesticides developed on the basis of it may be able to precisely act on the specific physiological processes of pests, making great contributions to the protection of crops, helping to increase agricultural production and reducing the damage of pests and diseases to crops.
Furthermore, in the field of materials science, it may be used as a synthetic raw material for functional materials. Due to its special chemical properties, it may endow materials with unique properties such as optics and electricity, providing opportunities for the development of new functional materials and promoting the progress and development of materials science. In short, this compound has important value in many scientific research and industrial production fields that cannot be ignored.

The synthesis method of 4-chloro-7- (3-chloropropoxy) -6-methoxyquinoline-3-formonitrile can be carried out according to the following method.
First take appropriate starting materials, such as quinoline compounds with specific substituents, and perform a series of chemical conversions based on them. At the beginning of the reaction, a halogenation reaction can be used to introduce chlorine atoms at specific locations in the raw material molecules. This halogenation reaction requires careful selection of halogenation reagents and reaction conditions. For example, with a suitable halogenating agent, the reaction is carried out in a specific temperature and solvent environment, so that the chlorine atoms can be accurately connected to the target check point to achieve 4-chlorine substitution. < Br >
Then, 3-chloropropoxy is introduced. A reagent containing 3-chloropropyl group structure can be selected to carry out nucleophilic substitution reaction with the halogenated quinoline derivative. In this step, the polarity of the solvent, the type and dosage of the base all have a great impact on the reaction process and yield. The reaction parameters should be carefully regulated to ensure that the 3-chloropropoxy group is successfully connected to the 7-position to generate the 7- (3-chloropropoxy) -4-chloroquinoline derivative.
Then, for the introduction of the 6-position methoxy group, a suitable methylating agent can be used to react with the aforementioned product under appropriate alkaline conditions. This methylation process requires strict control of the reaction temperature and time, so that the methoxy group is accurately added to the 6 position to obtain the intermediate of 4-chloro-7- (3-chloropropoxy) -6-methoxyquinoline.
Finally, the methonitrile group is introduced at the quinoline-3-position. It can be achieved by cyanidation reaction, and a suitable cyanidation reagent is selected to cyanide the 3-position in the presence of a catalyst to obtain 4-chloro-7- (3-chloropropoxy) -6-methoxyquinoline-3-methonitrile. After each step of the reaction, it is necessary to properly use separation and purification methods, such as column chromatography, recrystallization, etc., to ensure the purity of the product and provide high-quality raw materials for the next reaction, so that the synthesis of this compound can be completed.

4-Chloro-7- (3-chloropropoxy) -6-methoxyquinoline-3-formonitrile This substance has various physical properties. Its color state, at room temperature, or white to off-white crystalline powder, looks fine, like dust accumulation, with a certain luster, like morning dew reflected in fine sand. Its smell is light and slightly pungent, but it is not strongly intolerable.
The melting point is precisely determined to be between 110 ° C and 115 ° C. When heated, it gradually melts from the solid state, like ice disappearing under the warm sun, from solid to soft, and finally to liquid state. During this process, the state of matter gradually changes and the temperature rises steadily.
In terms of solubility, in organic solvents, such as dichloromethane and chloroform, it is quite soluble, just like salt dissolving in water, quietly and seamlessly. In methanol and ethanol, it also has a certain solubility, but it is slightly inferior to the former two. In water, the solubility is very small, like oil floating in water, it is difficult to blend. Due to its molecular structure characteristics, it has poor affinity with water molecules.
Density is also one of the important physical properties. Its density is about 1.35-1.45 g/cm ³, which is heavier than water. If placed in water, it sinks to the bottom of the water, like a stone falling into a deep pool.
In addition, its stability is acceptable, and it can maintain its own structure and properties under general environmental conditions. In case of strong acid, strong alkali, or extreme conditions such as high temperature and light, or chemical reactions, the structure changes and the properties are also different. In case of strong acid, or some chemical bonds in the molecule are broken, hydrolysis and other reactions occur, changing its original characteristics.

4-Chloro-7- (3-chloropropoxy) -6-methoxyquinoline-3-formonitrile, this is an organic compound with rich and diverse chemical properties.
From the perspective of physical properties, such organic compounds are often in solid form due to their relatively strong intermolecular forces. Its melting point and boiling point vary depending on the characteristics of the molecular structure. Generally speaking, the relative molecular weight of the molecule is large, and the polar groups in the structure, such as cyano (-CN), methoxy (-OCH), etc., will enhance the intermolecular forces, resulting in an increase in the melting point and boiling point.
In terms of chemical properties, the chlorine atom in its structure is significantly active. The chlorine atom on the aromatic ring has a certain nucleophilic substitution activity due to the influence of the electron cloud of the aromatic ring. In the presence of appropriate nucleophilic reagents, such as alkoxides and amines, and at suitable temperatures and alkali catalysis, the chlorine atom can be replaced by nucleophilic reagents to form a series of derivatives.
The chlorine atom in the 3-chloropropoxy group on the side chain has relatively higher activity, due to the different electronic effects on the carbon atom connected to the chlorine atom. Under alkaline conditions, substitution reactions are prone to occur, or under elimination reaction conditions, hydrogen chloride is removed to form double bonds. The electron cloud density distribution of the aromatic ring is affected by the methoxy group as the power supply group, which increases the electron cloud density of the adjacent and para-sites of the aromatic ring, so that these locations are more prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc., and the reactivity is different from that of quinoline derivatives without methoxy substitution.
Cyano (-CN) is another important functional group of this compound, and it can undergo a variety of reactions. Under acidic or basic conditions, cyano can be hydrolyzed to form carboxyl (-COOH) or amide (-CONH _ 2). In addition, cyanyl groups can also participate in nucleophilic addition reactions, react with compounds containing active hydrogen, such as water, alcohols, amines, etc., to form new nitrogen or oxygen-containing compounds.
In short, 4-chloro-7- (3-chloropropoxy) -6-methoxyquinoline-3-formonitrile has rich chemical reactivity due to its various functional groups, and has broad application potential in the field of organic synthesis.

I look at what you call "4 - Chloro - 7 - (3 - Chloro - Propoxy) - 6 - Methoxy - Quinoline - 3 - Carbonitrile", which is a chemical substance. However, it is not easy to know its market price range. Because the market price is easy, it often varies with many factors.
First, the purity of this substance is crucial. If the purity is very high, it is almost flawless, and its price is high; if it contains impurities, the price may drop. Second, the supply and demand conditions also affect its price. If there are many people in the world who want it, and there are few people who supply it, the price will surge; on the contrary, if the supply exceeds the demand, the price will slide.
Moreover, the price varies from region to region. The prosperous capital is Dayi, the merchants are convergent, the logistics is convenient, or the price may be different due to competition; and in remote places, the transportation is inconvenient, and the transportation fee is imposed on it, and the price is also different. Furthermore, the amount of purchase is also related to the price. If you buy in bulk, merchants may give discounts to promote sales; if you buy sporadically, the price may be difficult to drop.
As far as I know, the price of this material has not been determined in the current market. In order to obtain an accurate price, it is necessary to consult a wide range of chemical raw material merchants, trading houses, or visit chemical product trading platforms for detailed comparison before we can know the approximate price range. However, it is difficult to summarize this in a word and understand the exact price range.