4 Chloro 3 Nitroquinoline
quinoline thiophene imidazole thiazole

4-chloro-3-nitroquinoline

Taiy Chemical

    Specifications

    HS Code

    322472

    Chemical Formula C9H5ClN2O2
    Molar Mass 208.60 g/mol
    Appearance Yellow - solid
    Melting Point 145 - 147 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in organic solvents like dichloromethane, chloroform
    Cas Number 613-58-1
    Logp 3.09 (estimated)

    As an accredited 4-chloro-3-nitroquinoline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing
    Storage
    Shipping
    Free Quote

    Competitive 4-chloro-3-nitroquinoline prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365036030 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365036030

    Email: info@alchemist-chem.com

    General Information
    Where to Buy 4-chloro-3-nitroquinoline in China?
    As a trusted 4-chloro-3-nitroquinoline manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-chloro-3-nitroquinoline supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-chloro-3-nitroquinoline?
    4-Chloro-3-nitroquinoline is one of the organic compounds. It has a wide range of main uses and is often a key intermediate in the synthesis of many bioactive compounds in the field of medicinal chemistry. The structure of guinequinoline has unique biological activity and pharmacological properties. The introduction of chlorine and nitro functional groups can significantly change its physical and chemical properties and biological activities, so it is often an important starting material for the creation of new drugs.
    In the field of materials science, it may be involved in the preparation of functional materials. Due to the presence of chlorine and nitro groups, materials can be endowed with specific electronic properties and reactivity. For example, when used in the synthesis of organic optoelectronic materials, it has an impact on the optical and electrical properties of materials, and then expands its application in the field of optoelectronic devices, such as organic Light Emitting Diodes, solar cells, etc.
    Furthermore, in the field of organic synthetic chemistry, 4-chloro-3-nitroquinoline can serve as an important synthetic building block. With the reactivity of chlorine and nitro groups, more complex organic molecular structures can be constructed through various chemical reactions, such as nucleophilic substitution, reduction, etc., providing a rich material basis and reaction path for the development of organic synthetic chemistry. In conclusion, 4-chloro-3-nitroquinoline plays an indispensable role in many fields such as medicine, materials, and organic synthesis, and plays an important role in promoting scientific research and technological progress in related fields.
    What are the physical properties of 4-chloro-3-nitroquinoline?
    4-Chloro-3-nitroquinoline is also an organic compound. Its physical properties are as follows.
    Looking at its shape, under normal circumstances, it is mostly solid, which is caused by intermolecular forces. Its color, or light yellow to light brown, is due to the interaction of atoms and electrons in the molecular structure, which has specific absorption and reflection of light.
    As for the melting point, it is about a certain temperature range. The temperature value varies slightly due to the purity of the compound and the test conditions, but there is a certain range. This is determined by the binding force between molecules. To convert the solid state to the liquid state, the corresponding energy needs to be supplied to break the binding force.
    The boiling point is also an important physical property. When a certain temperature is reached, the compound changes from liquid to gaseous state. This process needs to overcome the attractive force between molecules, and its boiling point is related to the external pressure. Different pressures have different boiling points.
    In terms of solubility, in organic solvents such as ethanol and ether, there may be a certain solubility, due to the principle of "similar miscibility", its molecular structure has similar polarities to organic solvent molecules or can form interacting groups; while in water, the solubility is relatively low, because the molecular polarity matches the polarity of water molecules poorly, and it is difficult to form strong interactions between molecules.
    In addition, the density of 4-chloro-3-nitroquinoline has a specific value compared with water, which is related to its molecular weight and molecular accumulation mode. In many practical applications, density properties are also important considerations. The study and application of its physical properties in many fields such as chemical industry and medicine are of critical significance, which helps to control its separation, purification and reaction conditions.
    What is the chemical synthesis method of 4-chloro-3-nitroquinoline?
    The chemical synthesis of 4-chloro-3-nitroquinoline is a key issue in the field of organic synthesis. There are several common ways to synthesize this substance.
    One of them can be started by quinoline. Quinoline is introduced into the chlorine atom at position 4 through a specific halogenation reaction. In the halogenation reaction, a suitable halogenating reagent, such as a chlorine-containing reagent, is often used to selectively replace the hydrogen atom at position 4 under suitable reaction conditions, such as at a specific temperature and in the presence of a catalyst. Subsequently, the resulting product is nitrified and nitro is introduced at position 3. The nitrification reaction requires the selection of appropriate nitrifying reagents, such as mixed acid (mixture of nitric acid and sulfuric acid), and precise control of the reaction conditions to ensure that the nitro group is introduced to the No. 3 position, while avoiding excessive nitrification at other positions.
    Second, it can also be synthesized in the way of constructing a quinoline ring. First select the appropriate raw material to construct the quinoline ring structure through a multi-step reaction. In the process of constructing the ring, chlorine atoms and nitro groups can be introduced simultaneously or sequentially. For example, aniline compounds and suitable carbonyl compounds are used as starting materials to form a quinoline ring through a series of reactions such as condensation and cyclization. In the subsequent steps, chlorine atoms are introduced at the No. 4 position and nitro groups are introduced at the No. 3 position according to the reaction activity and selectivity. < Br >
    When synthesizing 4-chloro-3-nitroquinoline, it is crucial to control the reaction conditions. Temperature, reaction time, reagent dosage ratio, etc., all have a great impact on the reaction yield and product purity. In addition, the separation and purification of intermediates are also key steps to ensure the purity of the reaction products in each step, so that the next step can be smoothly advanced to obtain high-purity 4-chloro-3-nitroquinoline.
    4-chloro-3-nitroquinoline what are the precautions during use
    4-Chloro-3-nitroquinoline is also a chemical reagent. When using it, be careful about several things.
    First, it is related to safety. This is a toxic thing, which can be harmful to the body by touching it, smelling it or eating it. Therefore, when operating, protective gear must be used, such as gloves, masks, goggles, etc., to separate it from the body. And in a windy place, to prevent its gas from accumulating and harming the body.
    Second, about storage. It should be stored in a cool and dry place, avoiding fire and heat to prevent it from changing or exploding. It is also necessary to store it separately from other substances, especially those that are easy to react, such as alkalis and reducing agents, to prevent unexpected chemical reactions.
    Third, it involves operation. When using it, the amount must be accurate, and the equipment must be clean and suitable. The conditions of chemical reactions, such as temperature, time, and the proportion of agents, should be strictly controlled. After the reaction is completed, you should be careful when dealing with its waste, and follow the rules to discard it, so as not to pollute the environment.
    Fourth, discuss cognition. Before using it, you must know its properties, such as chemical properties, physical properties, and danger. Knowing its response to other things, you can know how to avoid danger and make things go smoothly, without risk. In short, with 4-chloro-3-nitroquinoline, careful word first, can be safe and sound.
    What is the market outlook for 4-chloro-3-nitroquinoline?
    4-Chloro-3-nitroquinoline is also an organic compound. At present, its market prospect is quite promising.
    From the perspective of the chemical industry, this compound has a wide range of uses. Due to its unique chemical structure, it is often a key intermediate in the synthesis of medicine. Medicine is related to people's livelihood and has a constant demand. When many new drugs are being developed, 4-chloro-3-nitroquinoline is often an indispensable material. Because of the pharmaceutical industry, its market demand is solid and growing.
    Furthermore, in the field of materials science, it has also emerged. It can participate in the synthesis of special functional materials. With the vigorous development of material science, the demand for specific energy materials is increasing. 4-chloro-3-nitroquinoline may be used in the preparation of new materials due to its characteristics, thereby expanding the market space.
    However, its market is not without challenges. The process of synthesizing this compound may involve complex reactions and conditions, and cost control is an important matter. If the cost is too high, it will hinder its large-scale application and marketing activities. And with stricter environmental regulations, the synthesis path needs to be more environmentally friendly and efficient in order to adapt to the times and maintain its market position.
    In summary, 4-chloro-3-nitroquinoline has broad market prospects due to its potential uses in medicine, materials and other fields, but it also needs to deal with problems such as cost and environmental protection in order to navigate the market.