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4-chloro-1-isobutyl-1h-imidazoben chemical structure of [4,5-c] quinoline
4-Chloro-1-isobutyl-1H-imidazo [4,5-c] quinoline (4-chloro-1-isobutyl-1H-imidazolo [4,5-c] quinoline) is one of the organic compounds. The chemical structure of this compound is quite complex, composed of several specific atomic groups connected in a specific way.
Looking at its structure, the core is imidazolo [4,5-c] quinoline parent nucleus. Quinoline is a nitrogen-containing heterocyclic aromatic hydrocarbon, which is fused by a benzene ring and a pyridine ring. In this compound, the quinoline structure is fused with the imidazole ring to form a unique fused ring system of imidazolo [4,5-c] quinoline.
is connected with isobutyl at the 1 position. Isobutyl is a branched alkyl group with the structure of -CH ² CH (CH 🥰) ³. The introduction of this alkyl group will affect the physical and chemical properties of the compound, such as changing its solubility, steric resistance, etc. At the
4 position, there are chlorine atoms connected. As an electron-absorbing group, chlorine atoms will affect the electron cloud distribution of the molecule, which in turn affects the reactivity, acidity and alkalinity of the compound.
In this way, 4-chloro-1-isobutyl-1H-imidazolo [4,5-c] quinoline is composed of imidazolo [4,5-c] quinoline parent nucleus, 1-position isobutyl and 4-position chlorine atoms. This structure also determines the unique chemical and physical properties of the compound, which may have important significance and potential application value in many fields such as organic synthesis and medicinal chemistry.
What are the physical properties of 4-chloro-1-isobutyl-1h-imidazoben [4,5-c] quinoline
4-Chloro-1-isobutyl-1H-imidazolo [4,5-c] quinoline is an organic compound. Its physical properties are of great research value.
Looking at its appearance, under room temperature and pressure, this substance is often in a solid state. Due to the force between molecules, its atoms and molecules are arranged in an orderly manner to form a stable solid state structure.
When it comes to melting point, the compound has a specific melting point value. The level of melting point is closely related to the molecular structure. In the molecular structure of this compound, the chemical bonds between atoms and the interactions between molecules jointly determine the melting point. The stronger the intermolecular force, the more energy is required to make the molecule break free from the lattice, and the higher the melting point.
Boiling point is also an important physical property. When the external pressure reaches a certain level, the temperature at which the compound changes from liquid to gaseous state is the boiling point. The boiling point is determined by factors such as intermolecular force and relative molecular weight. The greater the relative molecular weight, the stronger the intermolecular force, and the higher the boiling point is usually.
In terms of solubility, 4-chloro-1-isobutyl-1H-imidazolo [4,5-c] quinoline behaves differently in different solvents. Because its molecular structure contains specific functional groups, its solubility varies in polar solvents and non-polar solvents. In general, when polar functional groups are contained, the solubility is better in polar solvents such as alcohols and ketones; if the non-polar part accounts for a large proportion, the solubility is better in non-polar solvents such as hydrocarbons.
Density is also a physical property to be considered. Density reflects the mass of a substance per unit volume and is related to the molecular structure and packing method of the compound. Different crystal structures or molecular arrangements can cause differences in density.
In addition, the color state of this compound also needs attention. Although color is not explicitly mentioned, different purity or crystal forms may exhibit different colors, or be colorless and transparent, or slightly colored, which are all related to the internal structure and impurity conditions.
What are the main uses of 4-chloro-1-isobutyl-1h-imidazoben [4,5-c] quinoline?
4-Chloro-1-isobutyl-1H-imidazolo [4,5-c] quinoline is an organic compound. It has various uses and is often a key intermediate in drug research and development in the field of medicinal chemistry. Because of its specific chemical structure, it can interact with specific targets in organisms, so it is of great significance in the creation of new therapeutic drugs.
For example, in the exploration of anti-tumor drugs, this compound or because of its structural characteristics can precisely act on related proteins or signaling pathways in tumor cells to inhibit tumor cell proliferation and induce apoptosis, providing potential help for overcoming cancer problems. In the field of antimicrobial drug research, it may also destroy bacterial cell wall synthesis and interfere with bacterial metabolic processes by virtue of its unique chemical properties, thus demonstrating antibacterial activity and contributing to the fight against bacterial infections and diseases.
In the field of materials science, this compound may be applied to the research and development of new functional materials by virtue of its own characteristics. Or it can participate in the construction of materials with special optical and electrical properties, such as the preparation of fluorescent materials with unique luminescent properties, which can be used in optical sensors, display technology and other fields to promote the development of related technologies. In conclusion, 4-chloro-1-isobutyl-1H-imidazolo [4,5-c] quinoline has potential applications in many fields such as medicine and materials due to its unique structure, which is worthy of further investigation.
What are the synthesis methods of 4-chloro-1-isobutyl-1h-imidazoben [4,5-c] quinoline
To prepare 4-chloro-1-isobutyl-1H-imidazolo [4,5-c] quinoline, the method is as follows:
First, take an appropriate quinoline substrate and put it in a specific reaction vessel, followed by an appropriate amount of catalyst and reaction aids. The catalyst used, when it has the ability to catalyze efficiently, makes the reaction start and progress smoothly. Reaction aids can regulate the reaction environment, and help the substrate and the reactants work better.
Next, a chlorine-containing reagent is introduced, which must be pure and accurate to achieve the purpose of 4-position precise chlorination. When chlorinating, control the reaction temperature and duration. If the temperature is too high or side reactions occur, if it is too low, the reaction will be delayed. The duration also needs to be accurately controlled to ensure that the chlorination reaction is complete and not too much.
When chlorination is completed, introduce a reagent containing isobutyl and react with the chlorinated product to form a 1-isobutyl structure. This step also requires attention to the reaction conditions, such as the choice of solvent, which can fully dissolve the reactants without interfering with the reaction.
During the reaction process, thin-layer chromatography is often used to monitor the degree of reaction and adjust the reaction conditions in a timely manner. After the reaction is completed, the pure 4-chloro-1-isobutyl-1H-imidazolo [4,5-c] quinoline product is obtained by separation and purification techniques, such as column chromatography. During the operation, be sure to be careful and follow the specifications to ensure the safety of the experiment and the quality of the product.
4-chloro-1-isobutyl-1h-imidazoben [4,5-c] What are the precautions in the use of quinoline
4-Chloro-1-isobutyl-1H-imidazolo [4,5-c] quinoline has many things to pay attention to when using it.
The first thing to pay attention to is its chemical properties. This compound contains chlorine atoms and specific heterocyclic structures, and its chemical activity may be unique. When storing, it must be protected from high temperatures, open flames and strong oxidizing agents. Its structure may cause chemical reactions when exposed to heat or oxidizing agents, or even cause danger. For example, at high temperatures, chlorine atoms may be abnormally active, causing molecular structure changes and triggering unpredictable reactions.
Furthermore, it is related to its toxicity. Although the exact toxicity data of this compound is unknown, many heterocyclic compounds containing nitrogen and chlorine may have certain toxicity. When using, appropriate protective measures must be taken, such as protective clothing, gloves and goggles, to prevent skin contact and eye splashing. The operation is suitable for a well-ventilated environment. If it inhales dust or volatile gases, it may damage the respiratory system and other organs.
In addition, the experimental operation needs to be fine and rigorous. Due to the complex structure of this compound, it is crucial to control the conditions when participating in chemical reactions. Factors such as reaction temperature, pH, and reaction time can all have a significant impact on the reaction results. For example, high or low temperature, or abnormal reaction rate, impure product or low yield.
In addition, waste treatment after use cannot be ignored. Waste containing this compound should be properly disposed of in accordance with chemical waste treatment specifications, and should not be dumped at will to avoid polluting the environment. Or a special recycling process is required to ensure the safe disposal of harmful substances.
In short, when using 4-chloro-1-isobutyl-1H-imidazolo [4,5-c] quinoline, all links must be carefully handled from storage, protection, operation to waste disposal to ensure safety and smooth experimentation and production.