Chemical Formula | C10H10N2 |
Molar Mass | 158.2 g/mol |
Appearance | Solid |
Color | Typically colorless to pale yellow |
Odor | May have a characteristic amine - like odor |
Melting Point | Data may vary, but in a certain range |
Boiling Point | Also has a specific boiling point range |
Solubility In Water | Poorly soluble in water |
Solubility In Organic Solvents | Soluble in some organic solvents like ethanol, chloroform |
Density | Has a specific density value |
Pka | Has an associated pKa value related to its basicity |
What is the chemical structure of 4-amino-2-methylquinoline?
4-Amino-2-methylquinoline is 4-amino-2-methylquinoline, and its chemical structure is as follows.
Quinoline is originally a nitrogen-containing heterocyclic compound, and its structure is formed by fusing a benzene ring with a pyridine ring. In the quinoline structure, the nitrogen atom is located at the junction of the fused double ring, giving it unique chemical properties.
4-amino-2-methylquinoline, on this basic structure, is connected to a methyl group ($- CH_ {3} $) at position 2 and an amino group ($- NH_ {2} $) at position 4. Methyl is a saturated alkyl group, which has a certain electron-giving effect and can affect the distribution of molecular electron clouds. Amino is an electron-rich group, which can participate in a variety of chemical reactions, such as nucleophilic reactions and complexation with metal ions. The substitution of the two makes 4-amino-2-methylquinoline exhibit chemical activities and physical properties that are different from quinoline precursors. The uniqueness of its chemical structure determines its application and reaction characteristics in organic synthesis, pharmaceutical chemistry and other fields.
What are the physical properties of 4-amino-2-methylquinoline?
4-Amino-2-methylquinoline is one of the organic compounds. It has many physical properties. Looking at its properties, under normal temperature and pressure, it is mostly in a solid state, but it may vary depending on the specific environment. Its melting point is around [specific melting point value], which is the critical temperature at which the substance changes from solid to liquid. At this temperature, the force balance between molecules is broken, the lattice structure disintegrates, and the material form gradually changes.
As for the boiling point, it is roughly equal to [specific boiling point value]. At this temperature, the substance jumps from liquid to gas state, and the kinetic energy of the molecule increases greatly, which is enough to break free from the liquid phase. In terms of solubility, it may exhibit a certain solubility in common organic solvents such as ethanol and ether. Interactions such as hydrogen bonds and van der Waals forces can be formed between the molecular structure and the solvent molecules, so that it can be dispersed in the solvent medium.
Above the color, it is often white-like to light yellow, which is due to the arrangement of atoms and electron cloud distribution in the molecular structure, and the absorption and reflection characteristics of visible light. In addition, the density of 4-amino-2-methylquinoline or at [specific density value] characterizes the mass of the substance per unit volume, which is related to its characteristics such as fluctuation in different media. These physical properties are of great significance in the fields of organic synthesis, medicinal chemistry, and can provide a basis for their separation, purification, and application.
What are the common synthetic methods of 4-amino-2-methylquinoline?
4-Amino-2-methylquinoline is also an organic compound. Its common synthesis methods are briefly described.
One is through the Skraup reaction. First take o-toluidine and acaldehyde, use sulfuric acid as the catalyst, and co-heat at an appropriate temperature. This reaction process involves the addition of the double bond of the amino group and acaldehyde of o-toluidine, followed by a series of changes such as cyclization and dehydration, resulting in the prototype of 4-amino-2-methylquinoline. After appropriate refining steps, a pure product can be obtained.
The second can be achieved by the Friedländer synthesis method. Using 2-methyl-8-aminoquinoline as the starting material, it reacts with appropriate carbonyl compounds, such as acetaldehyde, in the catalytic environment of acid or base. During the reaction, the amino and carbonyl groups are condensed, and then cyclized within the molecule to construct the structure of 4-amino-2-methylquinoline. When catalyzed by bases, the reaction conditions are relatively mild; the reaction rate may be accelerated by acid catalysis, but it is necessary to pay attention to the occurrence of side reactions.
Third, Pfitzinger reaction can also be used. Using 2-methylquinoline-4-formic acid as the starting material, it reacts with ammonia and reducing agents, such as zinc powder, in a specific solvent. The carboxyl group of 2-methylquinoline-4-carboxylic acid first interacts with ammonia to form an amide intermediate, and then under the action of a reducing agent, the amide group is reduced to an amino group, and the final 4-amino-2-methylquinoline is obtained.
The synthesis methods have their own advantages and disadvantages. In practical application, the choice should be weighed according to many factors such as the availability of raw materials, cost, and product purity requirements.
4-amino-2-methylquinoline in what areas?
4-Amino-2-methylquinoline is useful in many fields.
In the field of medicine, this compound shows great potential. Due to its unique chemical structure, it may become a key raw material for the creation of new drugs. Geinquinoline compounds are often biologically active, and 4-amino-2-methylquinoline may play a role in targeting specific diseases, such as anti-tumor and antibacterial. In terms of anti-tumor, it may interfere with the proliferation and differentiation process of tumor cells, adding a strong boost to the research and development of anti-cancer drugs; in terms of antibacterial, it may inhibit specific physiological processes of bacteria and achieve antibacterial effect.
In the field of materials science, 4-amino-2-methylquinoline also has its uses. It can be used as an intermediate in organic synthesis, and through a series of chemical reactions, materials with special properties can be obtained. For example, it can participate in the preparation of photoelectric materials. Due to the electronic structure properties of the compound, it may affect the optical and electrical properties of the material, so that the prepared materials have good performance in Light Emitting Diode, solar cells and other devices, and improve their photoelectric conversion efficiency and other properties.
In the dye industry, 4-amino-2-methylquinoline can be used as an important component in the synthesis of new dyes. Its structure gives it unique color characteristics and chemical stability, or it can synthesize brightly colored and excellent fastness dyes, which are used in textiles, printing and dyeing and other industries to add brilliant colors to fabrics and other materials, and are not easy to fade after washing and lighting.
In addition, in the field of chemical research, 4-amino-2-methylquinoline is an important research object in organic synthetic chemistry. Chemists can use various chemical modifications and reactions to explore new chemical reaction mechanisms, expand organic synthesis methodologies, and promote the progress and development of chemical science.
In summary, 4-amino-2-methylquinoline plays an important role in many fields such as medicine, materials, dyes and chemical research, and has broad application prospects.
What is the market outlook for 4-amino-2-methylquinoline?
4-Amino-2-methylquinoline is one of the organic compounds. Its market prospect is quite promising in today's world.
Looking at the field of medicine, this compound has a unique chemical structure and is often the key raw material for the creation of new drugs. Today's world pays more and more attention to health, the pharmaceutical market demand is always booming, and the research and development of new drugs is in full swing. 4-Amino-2-methylquinoline may emerge in the research and development of anti-cancer, anti-infection and other drugs due to its characteristics. In the pharmaceutical market, its demand is expected to increase day by day.
Re-examining the realm of material science, with the rapid development of science and technology, the search for special performance materials has never stopped. 4-Amino-2-methylquinoline can be integrated into the material synthesis process by specific means, giving the material unique properties such as optics and electricity, and is suitable for many fields such as electronic devices and optical materials. This field is developing rapidly, and the demand for novel materials is endless. Therefore, 4-amino-2-methylquinoline also has broad development space in the materials science market.
However, its market prospects are not without challenges. The complexity and high cost of the synthesis process may hinder its large-scale application. To expand the market, it is necessary to optimize the synthesis path, reduce costs and increase efficiency. And the market competition is also severe, with many similar or alternative compounds competing for market share. Only by continuously improving technology and highlighting its own advantages can it stand tall in the market.
In summary, although 4-amino-2-methylquinoline faces challenges, its potential applications in fields such as medicine and materials science make its market prospects full of opportunities and hope. Over time, it may play a significant role in related industries.