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What is the main use of methyl 4- (4-fluorophenyl) -2-cyclopropylquinoline-3-carboxylate?
4- (4-hydroxybenzyl) -2-cyclopropylbenzoic acid light, this is a chemical substance related expression. The main uses of 3-ethyl lysine are as follows:
Ethyl lysine is an ester compound derived from lysine. As one of the essential amino acids in the human body, lysine plays a key role in many physiological processes, and ethyl lysine also has unique uses due to its own characteristics.
In the field of medicine, ethyl lysine is often used in the preparation of drugs. Because it is more fat-soluble, it is easier to penetrate biofilms than lysine, which helps to improve the absorption efficiency and bioavailability of drugs. For example, some therapeutic drugs for specific diseases can more effectively reach the target of action and enhance the efficacy of drugs with the help of the good membrane permeability of ethyl lysine. At the same time, it is also used in the formulation design of some nutritional supplements, which can improve the uptake and absorption of lysine by the human body, assist in maintaining normal physiological functions of the human body, such as promoting protein synthesis, assisting growth and development, and enhancing immunity.
In the chemical industry, ethyl lysine can act as a key intermediate in organic synthesis. With its active groups in its molecular structure, it can participate in a series of chemical reactions for the synthesis of organic compounds with more complex structures. These compounds play an important role in the preparation of fine chemical products, such as surfactants with special functions and new material additives. For example, through a specific reaction, ethyl lysine can be converted into a surfactant with unique properties, which can be used in daily chemical products or industrial production, showing good emulsification, dispersion and other properties.
In the food industry, ethyl lysine can be used as a food nutrient enhancer. In view of its nutritional function in the human body, adding it to food can improve the nutritional value of food and meet the additional needs of specific groups of people, such as infants, pregnant women, the elderly, etc. Moreover, compared with ordinary lysine, it may have better stability during food processing, which is conducive to the implementation of food processing technology and the maintenance of product quality.
What are the synthesis methods of methyl 4- (4-fluorophenyl) -2-cyclopropylquinoline-3-carboxylate?
To prepare ethyl 4- (4-hydroxybenzyl) -2-cyclopropyl benzoate, the following methods can be used:
First, ethyl 4-bromobenzoate and cyclopropyl boronic acid are used as the starting point. After Suzuki coupling reaction, ethyl 4- (cyclopropyl) benzoate is obtained first. After polyformaldehyde, zinc chloride and hydrochloric acid are used as agents, chloromethylation is carried out, and then condensation with phenol under alkaline conditions can be obtained. This way the raw materials are easy to buy, the reaction conditions are smooth, but the steps are slightly complicated, and fine temperature control and purification operations are required.
Second, starting from ethyl 4- (4-methoxybenzyl) -2-cyclopropyl benzoate, the product can be obtained by demethylation of boron tribromide. This diameter step is short and the yield is quite good. However, boron tribromide is highly corrosive and toxic, and has strict requirements for operation and protection.
Third, using 4- (4-hydroxyphenyl) -2-cyclopropylbenzoic acid and ethanol as materials, under the catalysis of concentrated sulfuric acid, the esterification reaction is carried out. This way is easy to operate, but the reaction is reversible. It needs to remove water or increase the amount of ethanol to promote the equilibrium right shift, and the concentrated sulfuric acid is highly corrosive, and the post-treatment is cumbersome.
Fourth, the esterification reaction was carried out with 4- (4-hydroxybenzyl) -2-cyclopropylbenzoic acid and ethanol, catalyzed by dicyclohexyl carbodiimide (DCC) and 4-dimethylaminopyridine (DMAP). The conditions are mild and the yield is high, but DCC is expensive, and the by-product dicyclohexyl urea is difficult to remove, so it needs to be properly handled.
All these methods have advantages and disadvantages. In actual preparation, it is necessary to weigh the factors such as raw material availability, cost, equipment conditions and product purity in detail, and choose the best.
What are the physical and chemical properties of methyl 4- (4-fluorophenyl) -2-cyclopropylquinoline-3-carboxylate?
Ethyl 4- (4-furyl) -2-cyclopropylbenzoate, also known as ethyl furan cyclopropanzoate, is an organic compound. Its physical and chemical properties are as follows:
Looking at its properties, it is mostly colorless to light yellow liquid at room temperature, with a bright appearance. This state is determined by intermolecular forces and structural characteristics. It has a special odor, although not strong and pungent, but it is unique and recognizable. This odor is derived from the synergistic action of various groups in the molecule.
In terms of its solubility, it exhibits good solubility in organic solvents such as ethanol, ether, dichloromethane, etc. Due to the principle of similar phase dissolution, its molecular structure is similar to that of organic solvents. However, the solubility in water is very small, and it is difficult to fuse with each other due to the large difference between the polarity of the water molecule and the molecular polarity of the compound.
When talking about the boiling point and the melting point, the boiling point is in a specific temperature range, and the specific value fluctuates according to the purity and environmental conditions. This is because the compound needs to overcome the intermolecular forces when boiling, and the structural characteristics determine the required energy, which in turn affects the boiling point. The melting point also has a corresponding value, which is the key temperature for the transition from solid to liquid, reflecting the orderly arrangement of molecules and the stability of the lattice.
Looking at the chemical stability, it is relatively stable under general conditions. However, under specific conditions such as strong acid, strong base or high temperature, strong oxidant, some chemical bonds in the molecular structure are easily affected, triggering chemical reactions. If the ester group can be hydrolyzed under acid-base catalysis, the furan ring and cyclopropyl group can also participate in specific reactions, which is caused by the chemical activity of each group.
In summary, the physicochemical properties of 4- (4-furyl) -2-cyclopropylbenzoate ethyl ester are determined by its unique molecular structure. These properties are of great significance in organic synthesis, drug development and other fields, and are related to its application efficiency and reaction path.
What is the market price of methyl 4- (4-fluorophenyl) -2-cyclopropylquinoline-3-carboxylate?
There are four things today, named 4- (4-hydroxybenzyl) -2-cyclopropylbenzoic acid and 3-carboxyacetamide, to know their price in the market. However, the price of the market often varies from time to place, and various factors interact, making it difficult to determine.
As for 4- (4-hydroxybenzyl) -2-cyclopropylbenzoic acid, the method of preparation, the level of purity, and the situation of supply and demand are all about the price. If the preparation is difficult, the materials used are expensive, and the purity is high, and there are many people who ask for it and few people who supply it, the price will be high; conversely, if the preparation is easy, the pure ones are more, and the needs are thin, the price will be low.
As for 3-carboxyacetamide, the same is true. It is used in the chemical industry, medicine and other industries, or as a material, and the price is more, and the price will change accordingly. The purity of its quality is also related to the price. The pure one has the best price, and the miscellaneous one has the inferior price.
To determine the price of these two in the market, when inquiring about the market of chemical raw materials, the establishment of pharmaceutical reagents, or interviewing the merchants who specialize in such things, you can also find relevant market information on the Internet, comprehensive comparison, and then you can get a more accurate price. However, the market situation changes like the situation, and the price may fluctuate overnight, so the price obtained is only temporary.
What are the storage conditions for methyl 4- (4-fluorophenyl) -2-cyclopropylquinoline-3-carboxylate?
"Tiangong Kaiwu" says: "All alum, sulfur, and nicotinite are produced in stone." However, the storage conditions of potassium borate square crystals and sodium calcium borate are rarely described in ancient books. Today's detailed investigation of physical properties, a brief overview.
potassium borate square crystals, relatively stable in nature, are afraid of moisture. Cover moisture can easily cause its deliquescence, which in turn damages its purity and structure. Therefore, when storing, it is advisable to choose a dry place and seal it to prevent water vapor from invading.
Sodium calcium borate, susceptible to heat, and sensitive to light. Exposed to strong light, or in a high temperature environment, its chemical properties are easy to change. It should be placed in a cool and dark place, and the temperature should not be too high to ensure its stable properties.
As for the storage device, neither potassium borate square crystal nor sodium calcium borate should be in direct contact with the metal material, for fear of chemical reaction. It is advisable to use glass or ceramic containers to hold it, and the cover of such materials is chemically stable and not incompatible with the two. In this way, potassium borate square crystal and sodium calcium borate can be stored for a long time without changing, for future use.