(3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

(3S) -7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, this is an organic compound. Looking at its name, its chemical structure can be gradually analyzed.
" (3S) " indicates that the configuration of the compound at the carbon atom at the third position is S-type, which depends on the Cahn-Ingold-Prelog rule, which is related to the arrangement of atoms or groups in the molecule in space.
"7-hydroxy", expressly stating that there is a hydroxy (-OH) substituent at the seventh position of the isoquinoline ring. The hydroxyl group is a common functional group, with polarity, and can participate in many chemical reactions, such as the formation of hydrogen bonds, which has a great influence on the physical and chemical properties of compounds.
"1,2,3,4-tetrahydroisoquinoline", indicating that the parent nucleus of this compound is an isoquinoline ring, and the double bonds of the 1, 2, 3, and 4 positions of the ring are all reduced, from the unsaturated isoquinoline ring to the more saturated tetrahydroisoquinoline ring. The isoquinoline ring is a heterocyclic structure containing nitrogen, which has certain aromatic properties and is common in many bioactive molecules and drugs.
"-3-carboxylic acid" refers to the presence of a carboxyl group (-COOH) at the third position of the tetrahydroisoquinoline ring. The carboxyl group is also an important functional group, which is acidic and can undergo reactions such as esterification and salt formation.
In summary, the chemical structure of (3S) -7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is: with 1,2,3,4-tetrahydroisoquinoline as the parent nucleus, the third position is of the S configuration and is connected with a carboxyl group, and the seventh position is connected with a hydroxyl group. This structure endows the compound with unique physical and chemical properties, which may be of great significance in the fields of organic synthesis and medicinal chemistry.

(3S) -7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, which is an organic compound with unique physical properties. It is mostly solid at room temperature, but the specific state is also affected by impurities and crystallization conditions.
Looking at its melting point, this is one of the important physical properties. Because the accurate determination of melting point requires experimental conditions to support, so the literature reports or experimental data are different. However, roughly speaking, its melting point is in a specific temperature range. At this temperature, the lattice structure of the compound is destroyed, and it gradually melts from a solid state to a liquid state.
In terms of solubility, it behaves differently in different solvents. In polar solvents such as water, because both hydroxyl groups in the molecule can form hydrogen bonds with water molecules, and carboxyl groups can be dissociated, it has certain solubility; in non-polar solvents such as n-hexane, due to the large difference between molecular polarity and non-polar solvents, the solubility is poor.
Furthermore, its appearance is often white to quasi-white crystalline powder, which is convenient for preliminary identification and judgment. However, it is difficult to determine its purity and structure by appearance alone, and it needs to be accurately characterized by modern analytical methods such as infrared spectroscopy and nuclear magnetic resonance.
In addition, the physical properties of the compound, such as density and stability, are also affected by molecular structure and external conditions. Functional groups such as hydroxyl and carboxyl groups in its molecules are active, and under specific temperature, pH and other conditions, chemical reactions may occur, which affects the stability.
In summary, the physical properties of (3S) -7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids are complex and interrelated. When studying and applying, various factors need to be comprehensively considered in order to deeply understand and rationally use this compound.

(3S) -7-hydroxy-1, 2, 3, 4-tetrahydroisoquinoline-3-carboxylic acid, which has attracted much attention in the field of medicine and chemistry research and has a wide range of uses.
In the process of pharmaceutical research and development, it is often a key intermediate. Gein has a unique structure and can be chemically modified to derive many biologically active compounds. It can also be used to create new neurological drugs, which can interact with neurotransmitter receptors to regulate nervous system function and have great significance for the treatment of neurological diseases such as Parkinson's disease and Alzheimer's disease.
In the field of organic synthesis, this compound is also an important cornerstone. Because it contains multiple activity checking points, chemists can use a variety of chemical reactions to finely carve its structure and build complex organic molecular structures. In the field of total synthesis of natural products, it may serve as a key module to help achieve the artificial synthesis of complex natural products, providing a material basis for in-depth research on the biological activities and pharmacological mechanisms of natural products.
Because of its chiral characteristics, it is also of great value in the field of asymmetric synthesis. Chiral compounds often have significant differences in biological activity in different configurations in fields such as drugs and pesticides. ( 3S) -7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid as a chiral raw material can participate in asymmetric catalytic reactions and efficiently prepare compounds with specific chiral configurations to meet the needs of chiral pure compounds in the pharmaceutical, pesticide and other industries.

The synthesis method of (3S) -7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid has various ways. Those who combine this compound in ancient times may follow the path of classical organic synthesis.
At the beginning, suitable starting materials are selected, such as benzene ring derivatives with specific substituents and nitrogen-containing heterocyclic precursors. With exquisite reaction techniques, the benzene ring is connected to the nitrogen-containing part, or by means of nucleophilic substitution or electrophilic substitution, and the skeleton of the target molecule is gradually constructed according to the established reaction mechanism.
In addition, catalytic reactions are used to help synthesize. Select a high-efficiency catalyst, or a metal catalyst, or an enzyme catalyst, under mild reaction conditions, to promote the smooth progress of the reaction and increase the selectivity and yield of the reaction. For example, the cyclization reaction catalyzed by metal forms a ring in the molecule to build the structure of isoquinoline.
Furthermore, the protective group strategy can be used. During the synthesis process, sensitive functional groups are protected to prevent them from participating in the reaction at an inappropriate time. When the reaction reaches an appropriate stage, the protective group is removed to expose the required functional group, and then the complete synthesis of the target molecule is completed.
There are also those who are guided by the concept of green synthesis. Choosing green solvents, such as ionic liquids, water, etc., instead of traditional toxic and harmful organic solvents, makes the synthesis process more environmentally friendly. And optimize the reaction conditions, reduce the reaction steps, reduce energy consumption, and make the synthesis more efficient and environmentally friendly.
There are many ways to synthesize (3S) -7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid. Synthesizers need to choose the optimal synthesis path according to their own conditions, raw material availability and target product requirements.

I think what you are asking is about the price of (3S) -7-hydroxy-1,2,3, 4-tetrahydroisoquinoline-3-carboxylic acid in the market. However, it is difficult to determine the market price of this compound. There are three reasons: First, the purity of this compound has a lot to do with it. If the purity is very high and almost perfect, the price will be high; if the purity is at a loss, the price will be slightly lower. Second, the difficulty of preparation is also the key. If the preparation process is complicated, time-consuming and high cost, the price will not be low; if the preparation is easy, the cost will drop and the price will also drop. Third, the state of market supply and demand determines the price. If the demand is strong and the supply is scarce, the price will rise; if the supply exceeds the demand, the price will fall.
As for the exact price, you need to visit a professional chemical reagent supplier, or consult the chemical raw material trading platform. There may be time and market to inform you of the current price of this compound. Or look at the records of past transactions for reference to determine the approximate price range. However, the market changes, and the price is not static, when real-time information shall prevail.