3s 4as 8as N Tert Butyldecahydroisoquinoline 3 Carboxamide
quinoline thiophene imidazole thiazole

(3S,4aS,8aS)-N-tert-butyldecahydroisoquinoline-3-carboxamide

Taiy Chemical

    Specifications

    HS Code

    632741

    Chemical Formula C15H28N2O
    Molecular Weight 252.395 g/mol
    Physical State Solid (predicted)
    Boiling Point Estimated around 375 - 385 °C at 760 mmHg
    Solubility Soluble in organic solvents like dichloromethane, chloroform; low solubility in water
    Density Estimated density around 1.0 - 1.1 g/cm³
    Pka The amide nitrogen may have a pKa value in the range of 15 - 18 (estimated for the conjugate acid of the amide group)
    Flash Point Estimated flash point around 180 - 190 °C

    As an accredited (3S,4aS,8aS)-N-tert-butyldecahydroisoquinoline-3-carboxamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

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    General Information
    Where to Buy (3S,4aS,8aS)-N-tert-butyldecahydroisoquinoline-3-carboxamide in China?
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    Frequently Asked Questions

    As a leading (3S,4aS,8aS)-N-tert-butyldecahydroisoquinoline-3-carboxamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of -N-tert-butyldecahydroisoquinoline-3-carboxamide?
    The chemical structure of (3S, 4aS, 8aS) -N-tert-butyl decahydroisoquinoline-3-formamide is quite subtle. Looking at its name, it can be gradually analyzed.
    This compound uses decahydroisoquinoline as the parent nucleus, which is a fused ring structure, which is like building the cornerstone of the whole chemical building. At the 3rd position of decahydroisoquinoline, a formamide group is connected, which is like a delicate component on the cornerstone. This formamide group, the structure of -CONH -, gives the compound unique chemical activity.
    At the nitrogen atom, tert-butyl is connected, and tert-butyl is a huge substituent, like the special decoration of a building. Its steric hindrance effect is significant, which has a great impact on the physical and chemical properties of the compound.
    As for its three-dimensional chemical structure, (3S, 4aS, 8aS) defines the spatial configuration of a specific atom. The existence of this configuration makes the compound unique in terms of chemical reactions and biological activities. Just like when building a building, each brick and stone is placed in a specific position, which determines the stability and function of the whole.
    (3S, 4aS, 8aS) -N-tert-butyl-decahydroisoquinoline-3-formamide chemical structure is the whole of the collaboration between each group and the three-dimensional configuration, which has unlimited research value and application potential in the field of organic chemistry.
    What are the physical properties of -N-tert-butyldecahydroisoquinoline-3-carboxamide?
    (3S, 4aS, 8aS) -N-tert-butyl decahydroisoquinoline-3-formamide is one of the organic compounds. Its physical properties, let me describe in detail.
    Looking at its properties, it is mostly white to white solid powder under normal conditions, which is determined by its intermolecular force and arrangement. The shape of the powder is conducive to dispersion and mixing in many reactions and applications, increasing its contact area with other substances, and promoting the progress of the reaction.
    When it comes to the melting point, it is between [X] ° C and [X] ° C. Melting point is the critical temperature at which a substance changes from solid to liquid. This property is an important indicator in the identification, separation and purification of compounds. If the purity is high, the melting point range is narrow and approaches the theoretical value; if it contains impurities, the melting point is reduced and the range is widened.
    As for solubility, this compound exhibits good solubility in common organic solvents such as dichloromethane and chloroform. It can be soluble in such solvents because the molecular structure and solvent molecules can form suitable interactions, such as van der Waals force, hydrogen bond, etc. In water, its solubility is poor, because the hydrophobic part of the molecule accounts for a large proportion, and it is difficult to form effective interactions with water molecules.
    Its density is about [X] g/cm ³, where the density is, the mass per unit volume of the substance reflects the degree of tight packing of molecules. This density value has certain reference value in the storage, transportation and related process design of substances.
    In addition, the stability of (3S, 4aS, 8aS) -N-tert-butyl decahydroisoquinoline-3-formamide is also an important physical property. In a dry environment at room temperature and pressure, the properties are relatively stable. However, when encountering extreme conditions such as high temperature, strong acid, and strong alkali, the molecular structure may change, causing its properties to change. Understanding these physical properties, as well as their synthesis, storage, and application, is of critical significance for researchers and practitioners to make good use of them.
    What are the common synthesis methods of (3S, 4aS, 8aS) -N-tert-butyldecahydroisoquinoline-3-carboxamide?
    The common synthesis methods of (3S, 4aS, 8aS) -N-tert-butyl decahydroisoquinoline-3-formamide cover a variety of. First, a suitable isoquinoline derivative can be started and hydrogenated to construct a decahydroisoquinoline skeleton. In the reaction, a suitable catalyst, such as palladium carbon or Raney nickel, is selected to hydrosaturate the unsaturated bond under a certain pressure and temperature to form the desired cyclic structure. Subsequently, the target molecule is constructed by introducing tert-butyl and formamide groups. The introduction of tert-butyl group can be achieved by nucleophilic substitution reaction with tert-butyl halide under the action of base; the introduction of formamide group can be achieved by the reaction of the corresponding carboxylic acid or acyl chloride with ammonia or amine compound.
    Second, it can also be synthesized by a stepwise cyclization strategy. First, the chain precursor containing a specific functional group is prepared, and the cyclization is achieved by an intramolecular reaction. For example, the decahydroisoquinoline mother nucleus is gradually constructed by the reaction between a suitable nucleophilic reagent and an electrophilic reagent to form a key carbon-carbon or carbon-heteroatomic bond. After that, tert-butyl and formamide groups are introduced in sequence. Careful selection of reaction conditions and reagents is required in each step to ensure the selectivity and yield of the reaction.
    Furthermore, transition metals can be used to catalyze the reaction. Transition metals such as palladium and copper can catalyze a variety of organic reactions, and different fragments can be connected to construct complex molecular structures through catalytic coupling reactions. For example, the amination reaction catalyzed by palladium can effectively realize the connection between nitrogen atoms and aromatic rings or alkenyl groups, providing an efficient path for the synthesis of target compounds. In this process, precise regulation of reaction conditions, such as reaction temperature, time, catalyst dosage, etc., is crucial to successfully obtain the target product.
    (3S, 4aS, 8aS) -N-tert-butyldecahydroisoquinoline-3-carboxamide in what areas?
    (3S, 4aS, 8aS) -N-tert-butyl decahydroisoquinoline-3-formamide, this is an organic compound, which has applications in many fields.
    In the field of medicine, it can be used as a drug intermediate. Gein organic compounds are often key starting materials or intermediates in drug synthesis, (3S, 4aS, 8aS) -N-tert-butyl decahydroisoquinoline-3-formamide or with specific chemical structure and activity, can be chemically modified and reacted to convert into drugs with therapeutic effect. For example, by modifying its structure to make it fit a specific target and be used to treat specific diseases.
    In the field of materials science, or participate in the preparation of new materials. Organic compounds can be used as basic units for the construction of polymer materials and composites. (3S, 4aS, 8aS) -N-tert-butyl decahydroisoquinoline-3-formamide can give materials special properties by virtue of its own characteristics, such as interaction with other substances, film-forming properties, etc., such as improving the mechanical properties, thermal stability or optical properties of materials.
    In the field of organic synthetic chemistry, it is an important research object. Due to its unique structure, it can be used to explore new synthesis methods and reaction paths. Chemists can expand organic synthesis strategies by studying its reactions, realize efficient construction of complex organic molecules, and promote the development of organic synthetic chemistry.
    What is the market outlook for -N-tert-butyldecahydroisoquinoline-3-carboxamide?
    Today there is (3S, 4aS, 8aS) -N-tert-butyl decahydroisoquinoline-3-formamide, which is worthy of detailed investigation in the city situation.
    The needs of the city are related to many fields. In the process of pharmaceutical research and development, because of its special structure or potential biological activity, it can contribute to the creation of novel drugs, so pharmaceutical researchers may have some requirements for it, hoping to explore its pharmacological wonders and open up new drug paths. This is one of the sources of demand.
    Furthermore, in the field of organic synthesis, it can be used as a key intermediate. Organic synthesis craftsmen use their unique structure to build more complex and delicate organic molecules, which demonstrate their value in the preparation of fine chemicals, etc., and attract the attention of the synthesis field, and the demand also arises.
    The state of supply is also the key point of the market. Those who produce this (3S, 4aS, 8aS) -N-tert-butyl decahydroisoquinoline-3-formamide need to have a sophisticated synthesis process. However, its synthesis or multi-step reaction involves strict conditions and high demands for technology and equipment. Only manufacturers with this strength can supply it stably.
    The state of inter-city competition also affects its scene. If there are few suppliers, and there are many people who need it, the price may rise, and the supplier can have an advantage; if the manufacturers compete, the supply will gradually increase, or the price will drop, and the buyer will benefit. And the new technology can enable producers to reduce costs and improve quality, and dominate the market.
    View of today, (3S, 4aS, 8aS) -N-tert-butyl decahydroisoquinoline-3-formamide is in the city, the demand is gradually emerging, the supply is limited by technology, the competition situation is still evolving, and its market scene is in a dynamic process. The future development depends on changes at both ends of supply and demand and technological innovation.