What is the chemical structure of (3S, 4aS, 8aS) -N- (1,1-dimethylethyl) decahydro-2- [ (2R, 3R) -2-hydroxy-3- [ (3-hydroxy-2-methylbenzoyl) amino] -4- (phenylthio) butyl] -3-isoquinolinformamide?

In terms of this chemical nomenclature, (3S, 4aS, 8aS) -N - (1,1-dimethylethyl) decahydro - 2 - [ (2R, 3R) - 2 -methoxy - 3 - [ (3 -methoxy - 2 -methylbenzyl) oxy] - 4 - (benzoyl) piperidine] - 3 -isobutylenyl piperidine is a structural expression of complex organic compounds.

To clarify its chemical structure, it is necessary to follow the nomenclature. ( 3S, 4aS, 8aS) and (2R, 3R) are the structural labels of chiral carbon atoms, which are related to the arrangement of atomic space. N - (1,1-dimethylethyl), indicating that nitrogen atoms are connected to specific substituents. Decahydro - 2 - [ (2R, 3R) - 2 - methoxy - 3 - [ (3 - methoxy - 2 - methylbenzyl) oxy] - 4 - (benzoyl) piperidyl] - 3 - isobutenoyl piperidine, the core structure is piperidine ring. The second position of the piperidine ring has specific substitutions, including methoxy, benzyloxy, etc., isobutenoyl at the third position, and benzoyl at the fourth position.

In summary, this compound takes the piperidine ring as the core and has many substitutions of methoxy, methyl, benzyl, benzoyl, isobutenoyl, etc. Chiral carbon atoms determine the spatial configuration and constitute a complex organic structure as a whole.

What are the physical properties of (3S, 4aS, 8aS) -N- (1,1-dimethylethyl) decahydro-2- [ (2R, 3R) -2-hydroxy-3- [ (3-hydroxy-2-methylbenzoyl) amino] -4- (phenylthio) butyl] -3-isoquinolinformamide?

(3S, 4aS, 8aS) -N- (1,1-dimethylethyl) decahydro-2- [ (2R, 3R) -2-methoxy-3- [ (3-methoxy-2-methylbenzoyl) amino] -4- (benzenesulfonyl) butyl] -3-isobutylbenzodihydropyran The physical properties of this compound are as follows:

The melting point of this compound is difficult to accurately determine due to the complex molecular structure and lack of relevant experimental data. However, the molecule contains multiple polar groups, such as methoxy, amino, sulfonyl, etc., which can enhance the intermolecular force, and the melting point may be in a higher range. < Br >
In terms of boiling point, due to the long carbon chain and various groups, the intermolecular force is complex, and its boiling point is expected to be quite high. Professional experiments are required to accurately determine under specific pressure conditions.

In terms of solubility, in view of the presence of polar methoxy, amino and non-polar benzene ring groups, it may have certain solubility in polar organic solvents such as methanol, ethanol, and acetone; in non-polar solvents such as n-hexane and cyclohexane, the solubility may be poor.

Density is also closely related to molecular structure, because it contains many atoms, relatively large molecular mass, and compact structure, and the density may be greater than that of common organic solvents. However, the specific value needs to be accurately calculated by experimental means and measured by volume and mass.

The physical properties of this compound are deeply affected by the type, quantity and spatial arrangement of groups in the molecular structure, and the exact physical property values should be subject to experimental measurements.

What are the main uses of (3S, 4aS, 8aS) -N- (1,1-dimethylethyl) decahydro-2- [ (2R, 3R) -2-hydroxy-3- [ (3-hydroxy-2-methylbenzoyl) amino] -4- (phenylthio) butyl] -3-isoquinolinformamide?

(3S, 4aS, 8aS) -N- (1,1-dimethylethyl) -decahydro-2- [ (2R, 3R) -2-methoxy-3- [ (3-methoxy-2-methylbenzyl) amino] -4- (benzoyl) butyl] -3-isoacrylonylbenzamide, which has a wide range of uses. In the field of medicine, it can be used as an active ingredient. It is exquisitely designed to target specific biomolecules or cellular pathways, or has therapeutic potential for specific diseases. For example, it uses its unique chemical structure to interact with the body's biological systems to regulate key physiological processes and bring hope for the treatment of related diseases. In the path of scientific research and exploration, it is like an important tool. Scientists use its characteristics to delve into the fields of biochemistry and cell biology, helping to reveal the hidden mysteries in organisms and contributing to related basic research. In the field of chemical production, it can act as a synthetic intermediate. With its special chemical properties, it plays a key role in a series of chemical reactions, and is transformed into other more complex and specific functional compounds through delicate reaction steps, providing support for the development of chemical product diversity. However, the specific use of this product must be accurately determined according to its detailed characteristics and practical application scenarios, in order to fully unlock its value in various fields.

What is the synthesis method of (3S, 4aS, 8aS) -N- (1,1-dimethylethyl) decahydro-2- [ (2R, 3R) -2-hydroxy-3- [ (3-hydroxy-2-methylbenzoyl) amino] -4- (phenylthio) butyl] -3-isoquinolinformamide?

To prepare (3S, 4aS, 8aS) -N- (1,1-dimethylethyl) -decahydro-2- [ (2R, 3R) -2-methoxy-3- [ (3-methoxy-2-methylbenzyl) amino] -4- (benzenesulfonyl) butyl] -3-isoacrylbenzamide, the following ancient methods can be used.

Take the appropriate starting material first and undergo many delicate transformations. For example, the raw material containing a specific chiral center undergoes various reactions such as condensation and substitution under suitable reaction conditions. When condensation, mild reagents and conditions are selected to precisely combine the functional groups and maintain the stability of the chiral center configuration. In the substitution reaction, select the appropriate substitution reagent and operate it under the appropriate solvent and temperature to ensure the accuracy of the substitution check point.

During the reaction process, the progress of the reaction needs to be carefully monitored. The consumption of raw materials and the generation of products can be monitored by means of thin-layer chromatography. If the reaction does not meet expectations, fine-tune the reaction conditions, such as temperature and reagent dosage, in a timely manner.

After the main reaction is completed, the product needs to be carefully purified. Column chromatography can be used to separate the product and impurities according to the different distribution coefficients of the product and the impurities in the stationary phase and the mobile phase, and obtain a pure target product. Each step requires finesse, and a slight difference in the pool may cause the product to be impure or to change the chiral configuration, resulting in the desired (3S, 4aS, 8aS) -N- (1,1-dimethylethyl) -decahydro-2- [ (2R, 3R) -2-methoxy-3- [ (3-methoxy-2-methylbenzyl) amino] -4- (benzenesulfonyl) butyl] -3-isopropenylbenzamide.

How safe is (3S, 4aS, 8aS) -N- (1,1-dimethylethyl) decahydro-2- [ (2R, 3R) -2-hydroxy-3- [ (3-hydroxy-2-methylbenzoyl) amino] -4- (phenylthio) butyl] -3-isoquinolinformamide?

Nowadays, there are (3S, 4aS, 8aS) -N- (1,1-dimethylethyl) decahydro-2 - [ (2R, 3R) -2 -methoxy-3 - [ (3-methoxy-2 -methylbenzyl) amino] -4 - (benzoyl) piperidine-1-yl] -3 -isobutenoyl indole. The investigation of its safety is related to many aspects.

To investigate the safety of this substance, the first thing to do is to clarify its chemical properties. To observe its structure, it is composed of complex groups, and such structures may affect its stability and reactivity. Interactions between groups, or chemical reactions under specific conditions, cause their properties to change, which is related to safety.

In pharmacological experiments, it is necessary to explore their effects on organisms. Take animals as models to observe their physiological reactions after ingestion. If it causes adverse reactions, such as organ damage, immune abnormalities, etc., its safety is worrying. And under different doses, the reaction may be different, so the dose-effect relationship is also key.

Furthermore, the environmental impact cannot be ignored. The decomposition and transformation of this substance in the environment will affect ecological safety. If the decomposition products are toxic or interfere with ecological balance, their safety in the environment is poor.

In addition, the preparation process is also related to safety. If dangerous raw materials are used and the conditions are severe, not only will there be safety hazards during production, but also the finished product or residual harmful substances will endanger the user.

In summary, to determine the safety of (3S, 4aS, 8aS) -N- (1,1-dimethylethyl) decahydro-2 - [ (2R, 3R) -2 -methoxy-3- [ (3-methoxy-2-methylbenzyl) amino] -4 - (benzoyl) piperidine-1-yl] -3 -isobutenoyl indoles, it is necessary to comprehensively consider the chemical properties, pharmacological reactions, environmental effects and preparation processes.