What is the chemical structure of (3S) 2- {N- [ (2S) -1-Ethoxy-1-oxo-4-phenylbutan-2-yl] -L-alanyl} -6,7-dimethoxy-1,2,3, 4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (1:1)

This is the chemical structure analysis of (3S) - 2 - {N - [ (2S) - 1 - ethoxy - 1 - oxo - 4 - phenylbutyl - 2 - yl] - L - alanyl} - 6,7 - dimethoxy - 1,2,3,4 - tetrahydroisoquinoline - 3 - carboxylic acid hydrochloride (1:1).

Looking at its name, it can be seen that this compound contains many functional groups and structural fragments. With tetrahydroisoquinoline as the core skeleton, it has a carboxyl group connected at the 3rd position and forms a hydrochloride form, that is, the carboxyl group forms a salt of hydrochloric acid. The 6 and 7 positions are each connected with a methoxy group, and the 2 positions are connected to another fragment through an amide bond. In this fragment, L-alanyl is an amino acid residue, and its nitrogen atom is connected to [ (2S) -1-ethoxy-1-oxo-4-phenylbutyl-2-yl]. The butyl moiety contains an ethoxy group and a carbonyl group, and the 4 positions are connected with a phenyl group. Each part is connected by a specific atom to exhibit a predetermined spatial configuration, such as the chiral central configuration shown in (3S) and (2S), which together constitute the chemical structure of this complex organic compound.

What are the physical properties of (3S) 2- {N- [ (2S) -1-Ethoxy-1-oxo-4-phenylbutan-2-yl] -L-alanyl} -6,7-dimethoxy-1,2,3, 4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (1:1)

(3S) -2-{ N- [ (2S) -1-ethoxy-1-oxo-4-phenylbutyl-2-yl] -L-alanyl} -6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (1:1), is an organic compound. Its physical properties are as follows: This compound is mostly solid under normal conditions, and its specific appearance may be white to off-white powder. Due to the interaction of various groups contained in its molecular structure, its molecules are arranged in an orderly manner to form a powder-like aggregate state.

When it comes to the melting point, it has been experimentally determined that the phase transition occurs within a specific temperature range. This temperature is the critical value of its solid and liquid states, which has a great impact on its stability and processing applications. In terms of solubility, its solubility in water is limited, because there are both hydrophilic carboxyl groups, amino groups and other polar groups in the molecule, but there are also hydrophobic aryl groups, long carbon chains and other non-polar parts. Under the balance of the two, the degree of solubility in water is not high; while in some organic solvents, such as dichloromethane, N, N-dimethylformamide, the solubility is relatively good, because the polarity and molecular structure of the organic solvent match with the compound, which is conducive to the interaction between molecules and promotes its dissolution. < Br >
Its density is also one of the important physical properties, reflecting its mass per unit volume. This property is closely related to the degree of molecular accumulation, which affects the space occupied by it in the preparation process and the ratio of materials. In addition, the hygroscopicity of the compound cannot be ignored. Because the polar groups in the molecule can interact with water molecules in the air, it may have a tendency to absorb water in a high humidity environment, which in turn affects its quality and stability.

What is the use of (3S) 2- {N- [ (2S) -1-Ethoxy-1-oxo-4-phenylbutan-2-yl] -L-alanyl} -6,7-dimethoxy-1,2,3, 4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (1:1)

(3S) - 2 - {N - [ (2S) - 1 - ethoxy - 1 - oxo - 4 - phenylbutyl - 2 - yl] - L - alanyl} - 6,7 - dimethoxy - 1,2,3,4 - tetrahydroisoquinoline - 3 - carboxylic acid hydrochloride (1:1), this medicine is mostly used in the medical tract. It is quite beneficial in the treatment of diseases. Because of human diseases, qi and blood meridians may be congested, and the function of the viscera may be uncoordinated. And this medicine reconciles qi and blood, dredges meridians and collaterals, and restores the power of the viscera. In case of qi stagnation and blood stasis, it can help to circulate qi and blood, dissipate stagnation, and make qi and blood flow unimpeded. Those who are transporting and losing their faculties in the spleen and stomach can also help them restore their ability to be healthy, so that the water and valley essence can be transported normally. Furthermore, for disorders of the nervous system, this medicine may regulate the nerves, make them return to a peaceful state, relieve discomforts such as insomnia and anxiety. Therefore, it can be seen in the treatment of various diseases and is commonly used by doctors to relieve the pain of the common people and help the health of the world.

What is the synthesis method of (3S) 2- {N- [ (2S) -1-Ethoxy-1-oxo-4-phenylbutan-2-yl] -L-alanyl} -6,7-dimethoxy-1,2,3, 4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (1:1)

The synthesis of (3S) - 2 - {N - [ (2S) - 1 - ethoxy - 1 - oxo - 4 - phenylbutyl - 2 - yl] - L - alanyl} - 6,7 - dimethoxy - 1,2,3,4 - tetrahydroisoquinoline - 3 - carboxylic acid hydrochloride (1:1) is a complex and delicate subject in the field of organic synthesis.

To synthesize this compound, the first focus should be on the construction of key intermediates. First, (2S) -1-ethoxy-1-oxo-4-phenylbutyl-2-yl related intermediates can be prepared from suitable starting materials through specific chemical reactions. This step may require the use of classical organic reactions such as nucleophilic substitution and redox, and the selection of suitable reagents and reaction conditions to ensure the high efficiency and selectivity of the reaction.

At the same time, for the 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid part, a carefully designed synthesis path is also required. Or the core structure can be gradually built by a multi-step reaction, starting from a simple aromatic hydrocarbon, through methoxylation, cyclization and other reactions.

Then, the above two key intermediates are connected by a condensation reaction to form a structure containing L-alanyl linkage. In this condensation reaction, attention should be paid to the protection and de-protection strategies of the reactive activity check point to avoid unnecessary side reactions.

Finally, the target product (3S) - 2 - {N - [ (2S) - 1 - ethoxy - 1 - oxo - 4 - phenylbutyl - 2 - yl] - L - alanyl} - 6,7 - dimethoxy - 1,2,3,4 - tetrahydroisoquinoline - 3 - carboxylic acid hydrochloride (1:1) was obtained by salt formation reaction with hydrochloric acid. The entire synthesis process requires careful regulation of each step of the reaction, precise control of reaction conditions, such as temperature, pH, reaction time, etc., and fine separation and purification of reaction products in order to obtain this target compound.

What is the market outlook for (3S) 2- {N- [ (2S) -1-Ethoxy-1-oxo-4-phenylbutan-2-yl] -L-alanyl} -6,7-dimethoxy-1,2,3, 4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (1:1)?

In today's market outlook, (3S) -2-{ N- [ (2S) -1-ethoxy-1-oxo-4-phenylbutyl-2-yl] -L-alanyl} -6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (1:1) has much to explore.

The market of medicine is unpredictable, and innovative drugs can always attract the attention of the world. If this compound has unique pharmacological activity, it may make a name for itself in the treatment of specific diseases. Looking at today's pharmaceutical market, there is a strong demand for new drugs. If they can be rigorously tested and proven to be effective and safe, they will definitely win the favor of doctors and patients, and the future will be bright.

However, the road to enter the market is not smooth. In the research and development stage, a lot of manpower, material and financial resources need to be invested, and many trials, such as cell experiments, animal experiments, and even multi-phase clinical trials, need to ensure efficacy and safety. Furthermore, the market competition is fierce, and there are many similar drugs or potential competitors. If you want to stand out, you must have unique advantages, such as better efficacy, fewer side effects, and affordable prices.

Although there are challenges ahead, opportunities also exist. If we can seize the opportunity, give full play to its characteristics, and actively expand the market, we may be able to add new color to the pharmaceutical industry and gain a place in the market.